PT970042E - 5-hidroximetil-2-aminotetralinas utilizadas como agentes cardiovasculares - Google Patents

5-hidroximetil-2-aminotetralinas utilizadas como agentes cardiovasculares

Info

Publication number
PT970042E
PT970042E PT98908052T PT98908052T PT970042E PT 970042 E PT970042 E PT 970042E PT 98908052 T PT98908052 T PT 98908052T PT 98908052 T PT98908052 T PT 98908052T PT 970042 E PT970042 E PT 970042E
Authority
PT
Portugal
Prior art keywords
pct
aminotetralins
hydroxymethyl
cardiovascular agents
sec
Prior art date
Application number
PT98908052T
Other languages
English (en)
Inventor
Paolo Cavalleri
Stefania Montanari
Francesco Santangelo
Francesco Marchini
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of PT970042E publication Critical patent/PT970042E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT98908052T 1997-02-26 1998-02-04 5-hidroximetil-2-aminotetralinas utilizadas como agentes cardiovasculares PT970042E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97MI000414A IT1289979B1 (it) 1997-02-26 1997-02-26 5-idrossimetil-6-idrossi-2-amminotetraline attive come agenti cardiovascolari

Publications (1)

Publication Number Publication Date
PT970042E true PT970042E (pt) 2002-06-28

Family

ID=11376182

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98908052T PT970042E (pt) 1997-02-26 1998-02-04 5-hidroximetil-2-aminotetralinas utilizadas como agentes cardiovasculares

Country Status (16)

Country Link
US (1) US6063964A (pt)
EP (1) EP0970042B1 (pt)
JP (1) JP2001513763A (pt)
KR (1) KR20000075736A (pt)
AT (1) ATE211727T1 (pt)
AU (1) AU733001B2 (pt)
CA (1) CA2282388A1 (pt)
DE (1) DE69803445T2 (pt)
DK (1) DK0970042T3 (pt)
ES (1) ES2169909T3 (pt)
HU (1) HUP0001058A3 (pt)
IT (1) IT1289979B1 (pt)
NO (1) NO994104L (pt)
NZ (1) NZ336680A (pt)
PT (1) PT970042E (pt)
WO (1) WO1998038155A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018371193B2 (en) 2017-11-24 2022-12-22 H. Lundbeck A/S New catecholamine prodrugs for use in the treatment of Parkinson's disease
US11130775B2 (en) 2019-05-20 2021-09-28 H. Lundbeck A/S Solid forms of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11168056B2 (en) 2019-05-20 2021-11-09 H. Lundbeck A/S Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[G]quinoline-6,7-diol
US11104697B2 (en) 2019-05-20 2021-08-31 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4AR,10AR)-7-hydroxy-1- propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11111263B2 (en) 2019-05-20 2021-09-07 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2803582A1 (de) * 1978-01-27 1979-08-02 Sandoz Ag Neue tetralinderivate, ihre herstellung und verwendung
IT1271411B (it) * 1993-09-14 1997-05-28 Zambon Spa Derivati del 2-ammino-1,2,3,4-tetraidro-naftalene attivi sul sistema cardiovascolare

Also Published As

Publication number Publication date
NO994104L (no) 1999-10-26
HUP0001058A2 (hu) 2001-06-28
ATE211727T1 (de) 2002-01-15
AU6619898A (en) 1998-09-18
US6063964A (en) 2000-05-16
AU733001B2 (en) 2001-05-03
EP0970042A1 (en) 2000-01-12
NZ336680A (en) 2000-02-28
ITMI970414A1 (it) 1998-08-26
WO1998038155A1 (en) 1998-09-03
NO994104D0 (no) 1999-08-25
KR20000075736A (ko) 2000-12-26
DK0970042T3 (da) 2002-04-29
HUP0001058A3 (en) 2001-07-30
DE69803445D1 (en) 2002-02-28
DE69803445T2 (de) 2002-08-29
JP2001513763A (ja) 2001-09-04
ES2169909T3 (es) 2002-07-16
EP0970042B1 (en) 2002-01-09
CA2282388A1 (en) 1998-09-03
IT1289979B1 (it) 1998-10-19

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