PT959906E - Corantes funcionais delta1,6 biciclo¬4.4.0| para intensificacao do contraste em imagiologia optica - Google Patents

Corantes funcionais delta1,6 biciclo¬4.4.0| para intensificacao do contraste em imagiologia optica

Info

Publication number
PT959906E
PT959906E PT97924641T PT97924641T PT959906E PT 959906 E PT959906 E PT 959906E PT 97924641 T PT97924641 T PT 97924641T PT 97924641 T PT97924641 T PT 97924641T PT 959906 E PT959906 E PT 959906E
Authority
PT
Portugal
Prior art keywords
alkyl
group
carboxylalkyl
alkoxyalkyl
hydroxyalkyl
Prior art date
Application number
PT97924641T
Other languages
English (en)
Inventor
Raghavan Rajagopalan
Ella Y Fung
Original Assignee
Mallinckrodt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc
Publication of PT959906E publication Critical patent/PT959906E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032Methine dyes, e.g. cyanine dyes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Indole Compounds (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Liquid Crystal (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
  • Optical Filters (AREA)
PT97924641T 1996-05-13 1997-05-09 Corantes funcionais delta1,6 biciclo¬4.4.0| para intensificacao do contraste em imagiologia optica PT959906E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/649,850 US5672333A (en) 1996-05-13 1996-05-13 Delta1,6 bicyclo 4,4,0! functional dyes for contrast enhancement in optical imaging

Publications (1)

Publication Number Publication Date
PT959906E true PT959906E (pt) 2004-01-30

Family

ID=24606485

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97924641T PT959906E (pt) 1996-05-13 1997-05-09 Corantes funcionais delta1,6 biciclo¬4.4.0| para intensificacao do contraste em imagiologia optica

Country Status (10)

Country Link
US (1) US5672333A (pt)
EP (1) EP0959906B1 (pt)
JP (1) JP2000510147A (pt)
AT (1) ATE249843T1 (pt)
CA (1) CA2254900A1 (pt)
DE (1) DE69725007T2 (pt)
DK (1) DK0959906T3 (pt)
ES (1) ES2202619T3 (pt)
PT (1) PT959906E (pt)
WO (1) WO1997042977A1 (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000095758A (ja) 1998-09-18 2000-04-04 Schering Ag 近赤外蛍光造影剤および蛍光造影方法
US20030180221A1 (en) * 1998-09-18 2003-09-25 Schering Ag Near infrared fluorescent contrast agent and fluorescence imaging
US7547721B1 (en) 1998-09-18 2009-06-16 Bayer Schering Pharma Ag Near infrared fluorescent contrast agent and fluorescence imaging
US6167297A (en) 1999-05-05 2000-12-26 Benaron; David A. Detecting, localizing, and targeting internal sites in vivo using optical contrast agents
US7198778B2 (en) 2000-01-18 2007-04-03 Mallinckrodt Inc. Tumor-targeted optical contrast agents
US20080233050A1 (en) * 2000-01-18 2008-09-25 Mallinckrodt Inc. Diagnostic and therapeutic optical agents
US6395257B1 (en) 2000-01-18 2002-05-28 Mallinckrodt Inc. Dendrimer precursor dyes for imaging
US6939532B2 (en) 2000-01-18 2005-09-06 Mallinckrodt, Inc. Versatile hydrophilic dyes
US6180087B1 (en) 2000-01-18 2001-01-30 Mallinckrodt Inc. Tunable indocyanine dyes for biomedical applications
US6180086B1 (en) 2000-01-18 2001-01-30 Mallinckrodt Inc. Hydrophilic cyanine dyes
US7790144B2 (en) * 2000-01-18 2010-09-07 Mallinckrodt Inc. Receptor-avid exogenous optical contrast and therapeutic agents
US6748259B1 (en) * 2000-06-15 2004-06-08 Spectros Corporation Optical imaging of induced signals in vivo under ambient light conditions
US20040180809A1 (en) * 2000-10-16 2004-09-16 Mallinckrodt Inc. Tissue-specific exogenous optical agents
US20070092450A1 (en) * 2000-10-16 2007-04-26 Mallinckrodt Inc. Tissue-specific exogenous optical agents
US20040143190A1 (en) * 2003-01-22 2004-07-22 Schnitzer Mark J. Mapping neural and muscular electrical activity
US20100022449A1 (en) * 2006-03-09 2010-01-28 Mallinckrodt Inc. Receptor-avid exogenous optical contrast and therapeutic agents
US20110177007A1 (en) * 2008-09-29 2011-07-21 Raghavan Rajagopalan Dithienopyrrole Dyes for Imaging and Therapy
US20110177006A1 (en) * 2008-09-29 2011-07-21 Raghavan Rajagopalan Dithienofuran Dyes for Imaging and Therapy
WO2010037067A1 (en) * 2008-09-29 2010-04-01 Mallinckrodt Inc. Fused ring thiophene dyes for imaging and therapy
WO2010121003A1 (en) 2009-04-16 2010-10-21 Mallinckrodt Inc. Pyrazine derivatives for optical imaging and therapy
WO2010132554A2 (en) 2009-05-12 2010-11-18 Mallinckrodt Inc. Diaza heterocyclic compounds for phototherapy
WO2010132515A1 (en) 2009-05-12 2010-11-18 Mallinckrodt Inc. Compounds containing acyclic n-n bonds for phototherapy
WO2011031955A2 (en) 2009-09-11 2011-03-17 Mallinckrodt Inc. Optical monitoring of leukemia
WO2011035140A1 (en) 2009-09-18 2011-03-24 Paka Pulmonary Pharmaceuticals, Inc. Methods and compositions for delivery of contrast moieties to the lungs
WO2011060113A1 (en) 2009-11-11 2011-05-19 Mallinckrodt Inc. Sulfenamide compounds for phototherapy
WO2011084571A2 (en) 2009-12-16 2011-07-14 Mallinckrodt Inc. Azide derivatives for phototherapy

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4762701A (en) * 1986-10-31 1988-08-09 Smithkline Beckman Corporation In vivo cellular tracking
FR2682498A1 (fr) * 1991-10-15 1993-04-16 Kodak Pathe Colorants comprenant des macrocycles thioethers.
EP0565121B1 (en) * 1992-04-09 1999-07-14 Fuji Photo Film Co., Ltd. Silver halide photographic light-sensitive material
DE4301106A1 (de) * 1993-01-18 1994-07-21 Agfa Gevaert Ag Farbfotografisches Aufzeichnungsmaterial
WO1995023355A1 (en) * 1994-02-28 1995-08-31 Minnesota Mining And Manufacturing Company Sensitizers for photothermographic elements

Also Published As

Publication number Publication date
WO1997042977A1 (en) 1997-11-20
JP2000510147A (ja) 2000-08-08
ATE249843T1 (de) 2003-10-15
ES2202619T3 (es) 2004-04-01
DK0959906T3 (da) 2003-12-08
CA2254900A1 (en) 1997-11-20
US5672333A (en) 1997-09-30
DE69725007D1 (de) 2003-10-23
EP0959906A4 (pt) 1999-12-22
EP0959906A1 (en) 1999-12-01
EP0959906B1 (en) 2003-09-17
DE69725007T2 (de) 2004-07-08

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