PT92813A - Processo para a preparacao de novos derivados de bisarilalcenos - Google Patents
Processo para a preparacao de novos derivados de bisarilalcenosInfo
- Publication number
- PT92813A PT92813A PT92813A PT9281390A PT92813A PT 92813 A PT92813 A PT 92813A PT 92813 A PT92813 A PT 92813A PT 9281390 A PT9281390 A PT 9281390A PT 92813 A PT92813 A PT 92813A
- Authority
- PT
- Portugal
- Prior art keywords
- radical
- optionally substituted
- formula
- image
- pyridyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/04—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with only hydrogen atoms, halogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8900213A FR2643373B1 (fr) | 1989-01-10 | 1989-01-10 | Nouveaux derives des bisarylalcenes, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT92813A true PT92813A (pt) | 1990-07-31 |
| PT92813B PT92813B (pt) | 1995-12-29 |
Family
ID=9377578
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT92813A PT92813B (pt) | 1989-01-10 | 1990-01-09 | Processo para a preparacao de novos derivados de bisarilalcenos |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US5028607A (pt) |
| EP (1) | EP0378468B1 (pt) |
| JP (1) | JPH06102659B2 (pt) |
| AT (1) | ATE112775T1 (pt) |
| AU (1) | AU620195B2 (pt) |
| CA (1) | CA2007401A1 (pt) |
| DE (1) | DE69013173T2 (pt) |
| DK (1) | DK0378468T3 (pt) |
| ES (1) | ES2064670T3 (pt) |
| FR (1) | FR2643373B1 (pt) |
| IE (1) | IE64792B1 (pt) |
| NZ (1) | NZ231823A (pt) |
| OA (1) | OA09435A (pt) |
| PT (1) | PT92813B (pt) |
| ZA (1) | ZA9055B (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2644786B1 (fr) * | 1989-03-21 | 1993-12-31 | Adir Cie | Nouveaux derives fluoro-4 benzoiques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
| PT637306E (pt) * | 1992-04-23 | 2001-10-30 | Merrell Pharma Inc | 4-imidometil-1-¬2'-fenil-2'-oxoetil|-piperidinas como antagonistas 5ht2 da serotonina sua preparacao e sua utilizacao em terapeutica |
| FR2699176B1 (fr) * | 1992-12-11 | 1995-03-03 | Adir | Nouveaux composés bicycliques de pyrimidine, leur procédé de préparation et les compositions pharmaceutiques les renfermant. |
| CN1218368A (zh) * | 1996-03-15 | 1999-06-02 | 伊莱利利公司 | 治疗感冒或过敏性鼻炎的方法 |
| US5869497A (en) * | 1996-03-15 | 1999-02-09 | Eli Lilly And Company | Method of treating or ameliorating the symptoms of common cold or allergic rhinitis |
| US7244843B2 (en) * | 2003-10-07 | 2007-07-17 | Bristol-Myers Squibb Company | Modulators of serotonin receptors |
| WO2023003497A1 (ru) * | 2021-07-23 | 2023-01-26 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Соединения с лизосомотропной и противовирусной активностью |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE794596A (fr) * | 1972-01-28 | 1973-05-16 | Richardson Merrell Inc | Piperidinoalcanone-oximes substituees et leur procede de preparation |
| US4485107A (en) * | 1982-11-01 | 1984-11-27 | Janssen Pharmaceutica N.V. | [[Bis(aryl)methylene]-1-piperidinyl]alkyl-pyrimidinones |
| US4540780A (en) * | 1983-06-02 | 1985-09-10 | Warner-Lambert Company | Diphenylmethylene piperidines |
| FR2571722B1 (fr) * | 1984-10-16 | 1986-12-26 | Synthelabo | Derives de benzimidazolone, leur preparation et leur application en therapeutique |
| DE3563964D1 (en) * | 1984-10-16 | 1988-09-01 | Synthelabo | Piperidine derivatives, their preparation and their therapeutical application |
| EP0222191B1 (de) * | 1985-11-11 | 1991-01-30 | ASTA Pharma AG | 4-Benzyl-1-(2H)-phthalazinon-Derivate |
| EP0235463A3 (en) * | 1985-12-20 | 1990-01-17 | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) | N-substituted-arylalkyl and arylalkylene piperidines as cardiovascular antihistaminic and antisecretory agents |
| FR2605008B1 (fr) * | 1986-10-08 | 1988-12-02 | Synthelabo | Derives d'imidazo (4,5-b)pyridinone-2, leur preparation et leur application en therapeutique |
| FR2614021B1 (fr) * | 1987-04-14 | 1991-03-01 | Andre Buzas | Derives de la 1-((1,1-diphenyl)-1-alcenyl)-piperazine, procede d'obtention et compositions pharmaceutiques les contenant |
-
1989
- 1989-01-10 FR FR8900213A patent/FR2643373B1/fr not_active Expired - Lifetime
- 1989-12-18 NZ NZ231823A patent/NZ231823A/en unknown
-
1990
- 1990-01-04 IE IE2790A patent/IE64792B1/en not_active IP Right Cessation
- 1990-01-04 US US07/460,751 patent/US5028607A/en not_active Expired - Fee Related
- 1990-01-04 ZA ZA9055A patent/ZA9055B/xx unknown
- 1990-01-09 PT PT92813A patent/PT92813B/pt not_active IP Right Cessation
- 1990-01-09 DE DE69013173T patent/DE69013173T2/de not_active Expired - Fee Related
- 1990-01-09 CA CA002007401A patent/CA2007401A1/fr not_active Abandoned
- 1990-01-09 EP EP90400056A patent/EP0378468B1/fr not_active Expired - Lifetime
- 1990-01-09 ES ES90400056T patent/ES2064670T3/es not_active Expired - Lifetime
- 1990-01-09 DK DK90400056.9T patent/DK0378468T3/da active
- 1990-01-09 AT AT90400056T patent/ATE112775T1/de not_active IP Right Cessation
- 1990-01-09 JP JP2002408A patent/JPH06102659B2/ja not_active Expired - Lifetime
- 1990-01-09 AU AU47810/90A patent/AU620195B2/en not_active Ceased
- 1990-01-10 OA OA59724A patent/OA09435A/xx unknown
- 1990-08-24 US US07/572,858 patent/US5079249A/en not_active Expired - Fee Related
- 1990-08-24 US US07/573,338 patent/US5071847A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US5071847A (en) | 1991-12-10 |
| CA2007401A1 (fr) | 1990-07-10 |
| DE69013173D1 (de) | 1994-11-17 |
| ES2064670T3 (es) | 1995-02-01 |
| US5079249A (en) | 1992-01-07 |
| NZ231823A (en) | 1992-03-26 |
| DE69013173T2 (de) | 1995-05-24 |
| JPH02225481A (ja) | 1990-09-07 |
| IE900027L (en) | 1990-07-10 |
| FR2643373B1 (fr) | 1993-12-31 |
| DK0378468T3 (da) | 1995-03-20 |
| IE64792B1 (en) | 1995-09-06 |
| EP0378468A2 (fr) | 1990-07-18 |
| ATE112775T1 (de) | 1994-10-15 |
| EP0378468B1 (fr) | 1994-10-12 |
| AU4781090A (en) | 1990-08-30 |
| ZA9055B (en) | 1990-10-31 |
| EP0378468A3 (fr) | 1991-09-11 |
| JPH06102659B2 (ja) | 1994-12-14 |
| AU620195B2 (en) | 1992-02-13 |
| OA09435A (fr) | 1992-10-15 |
| PT92813B (pt) | 1995-12-29 |
| FR2643373A1 (fr) | 1990-08-24 |
| US5028607A (en) | 1991-07-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19950911 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19990331 |