DE69013173D1 - Bisarylalkenderivate, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzung, die sie enthalten. - Google Patents
Bisarylalkenderivate, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzung, die sie enthalten.Info
- Publication number
- DE69013173D1 DE69013173D1 DE69013173T DE69013173T DE69013173D1 DE 69013173 D1 DE69013173 D1 DE 69013173D1 DE 69013173 T DE69013173 T DE 69013173T DE 69013173 T DE69013173 T DE 69013173T DE 69013173 D1 DE69013173 D1 DE 69013173D1
- Authority
- DE
- Germany
- Prior art keywords
- radical
- optionally substituted
- formula
- image
- pyridyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/04—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with only hydrogen atoms, halogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8900213A FR2643373B1 (fr) | 1989-01-10 | 1989-01-10 | Nouveaux derives des bisarylalcenes, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69013173D1 true DE69013173D1 (de) | 1994-11-17 |
DE69013173T2 DE69013173T2 (de) | 1995-05-24 |
Family
ID=9377578
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69013173T Expired - Fee Related DE69013173T2 (de) | 1989-01-10 | 1990-01-09 | Bisarylalkenderivate, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzung, die sie enthalten. |
Country Status (15)
Country | Link |
---|---|
US (3) | US5028607A (de) |
EP (1) | EP0378468B1 (de) |
JP (1) | JPH06102659B2 (de) |
AT (1) | ATE112775T1 (de) |
AU (1) | AU620195B2 (de) |
CA (1) | CA2007401A1 (de) |
DE (1) | DE69013173T2 (de) |
DK (1) | DK0378468T3 (de) |
ES (1) | ES2064670T3 (de) |
FR (1) | FR2643373B1 (de) |
IE (1) | IE64792B1 (de) |
NZ (1) | NZ231823A (de) |
OA (1) | OA09435A (de) |
PT (1) | PT92813B (de) |
ZA (1) | ZA9055B (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2644786B1 (fr) * | 1989-03-21 | 1993-12-31 | Adir Cie | Nouveaux derives fluoro-4 benzoiques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
DE69330272T2 (de) * | 1992-04-23 | 2001-10-25 | Merrell Pharma Inc | 4-imidomethyl-1-[2'-phenyl-2-oxoethyl]-piperidine als serotonin-5ht2-antagonisten, ihre herstellung und therapeutische anwendung |
FR2699176B1 (fr) * | 1992-12-11 | 1995-03-03 | Adir | Nouveaux composés bicycliques de pyrimidine, leur procédé de préparation et les compositions pharmaceutiques les renfermant. |
US5869497A (en) * | 1996-03-15 | 1999-02-09 | Eli Lilly And Company | Method of treating or ameliorating the symptoms of common cold or allergic rhinitis |
CN1218368A (zh) * | 1996-03-15 | 1999-06-02 | 伊莱利利公司 | 治疗感冒或过敏性鼻炎的方法 |
US7244843B2 (en) * | 2003-10-07 | 2007-07-17 | Bristol-Myers Squibb Company | Modulators of serotonin receptors |
CN117677386A (zh) * | 2021-07-23 | 2024-03-08 | 瓦伦塔有限责任公司 | 具有亲溶酶体和抗病毒活性的化合物 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE794596A (fr) * | 1972-01-28 | 1973-05-16 | Richardson Merrell Inc | Piperidinoalcanone-oximes substituees et leur procede de preparation |
US4485107A (en) * | 1982-11-01 | 1984-11-27 | Janssen Pharmaceutica N.V. | [[Bis(aryl)methylene]-1-piperidinyl]alkyl-pyrimidinones |
US4540780A (en) * | 1983-06-02 | 1985-09-10 | Warner-Lambert Company | Diphenylmethylene piperidines |
FR2571722B1 (fr) * | 1984-10-16 | 1986-12-26 | Synthelabo | Derives de benzimidazolone, leur preparation et leur application en therapeutique |
DE3563964D1 (en) * | 1984-10-16 | 1988-09-01 | Synthelabo | Piperidine derivatives, their preparation and their therapeutical application |
EP0222191B1 (de) * | 1985-11-11 | 1991-01-30 | ASTA Pharma AG | 4-Benzyl-1-(2H)-phthalazinon-Derivate |
EP0228893A3 (de) * | 1985-12-20 | 1990-01-03 | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) | Durch Aryloxyalkyl-Gruppen N-substituierte Arylalkyl heterozyklische Amine in Allergieheilverfahren |
FR2605008B1 (fr) * | 1986-10-08 | 1988-12-02 | Synthelabo | Derives d'imidazo (4,5-b)pyridinone-2, leur preparation et leur application en therapeutique |
FR2614021B1 (fr) * | 1987-04-14 | 1991-03-01 | Andre Buzas | Derives de la 1-((1,1-diphenyl)-1-alcenyl)-piperazine, procede d'obtention et compositions pharmaceutiques les contenant |
-
1989
- 1989-01-10 FR FR8900213A patent/FR2643373B1/fr not_active Expired - Lifetime
- 1989-12-18 NZ NZ231823A patent/NZ231823A/en unknown
-
1990
- 1990-01-04 IE IE2790A patent/IE64792B1/en not_active IP Right Cessation
- 1990-01-04 US US07/460,751 patent/US5028607A/en not_active Expired - Fee Related
- 1990-01-04 ZA ZA9055A patent/ZA9055B/xx unknown
- 1990-01-09 CA CA002007401A patent/CA2007401A1/fr not_active Abandoned
- 1990-01-09 AU AU47810/90A patent/AU620195B2/en not_active Ceased
- 1990-01-09 DK DK90400056.9T patent/DK0378468T3/da active
- 1990-01-09 JP JP2002408A patent/JPH06102659B2/ja not_active Expired - Lifetime
- 1990-01-09 ES ES90400056T patent/ES2064670T3/es not_active Expired - Lifetime
- 1990-01-09 AT AT90400056T patent/ATE112775T1/de not_active IP Right Cessation
- 1990-01-09 EP EP90400056A patent/EP0378468B1/de not_active Expired - Lifetime
- 1990-01-09 PT PT92813A patent/PT92813B/pt not_active IP Right Cessation
- 1990-01-09 DE DE69013173T patent/DE69013173T2/de not_active Expired - Fee Related
- 1990-01-10 OA OA59724A patent/OA09435A/xx unknown
- 1990-08-24 US US07/573,338 patent/US5071847A/en not_active Expired - Fee Related
- 1990-08-24 US US07/572,858 patent/US5079249A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US5028607A (en) | 1991-07-02 |
IE900027L (en) | 1990-07-10 |
FR2643373A1 (fr) | 1990-08-24 |
DE69013173T2 (de) | 1995-05-24 |
AU620195B2 (en) | 1992-02-13 |
DK0378468T3 (da) | 1995-03-20 |
PT92813B (pt) | 1995-12-29 |
JPH06102659B2 (ja) | 1994-12-14 |
EP0378468B1 (de) | 1994-10-12 |
US5071847A (en) | 1991-12-10 |
ES2064670T3 (es) | 1995-02-01 |
NZ231823A (en) | 1992-03-26 |
US5079249A (en) | 1992-01-07 |
ZA9055B (en) | 1990-10-31 |
JPH02225481A (ja) | 1990-09-07 |
PT92813A (pt) | 1990-07-31 |
FR2643373B1 (fr) | 1993-12-31 |
EP0378468A2 (de) | 1990-07-18 |
AU4781090A (en) | 1990-08-30 |
ATE112775T1 (de) | 1994-10-15 |
OA09435A (fr) | 1992-10-15 |
IE64792B1 (en) | 1995-09-06 |
EP0378468A3 (de) | 1991-09-11 |
CA2007401A1 (fr) | 1990-07-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE144503T1 (de) | Thiazolidin-2,4-dionderivate, verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen | |
DE59103595D1 (de) | Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel. | |
OA09199A (fr) | "Nouveaux dérivés fluoro-4 benzoïques, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent". | |
ATE125252T1 (de) | Cyano-2-hydroxy-3-enamid-derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, diese enthaltende pharmazeutische zusammensetzungen und erhaltene zwischenprodukte. | |
FR2679906B1 (fr) | Nouvelles (isoquinolein-5 yl) sulfonamides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. | |
GR3023936T3 (en) | Heterocyclic alkylamides, process for their preparation and pharmaceutical compositions containing them | |
DE58908892D1 (de) | Indolocarbazol-Derivate, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel. | |
FI933903A0 (fi) | Substituerade cyklohexanderivat, foerfarande foer framstaellning daerav och anvaendning av foereningar foer behandling av sjukdomar | |
AU656466B2 (en) | New benzimidazole compounds, a process for their preparation and pharmaceutical compositions containing them | |
ATE71617T1 (de) | Chinolinonderivate, ihre herstellung und ihre verwendung als arzneimittel. | |
ATE110365T1 (de) | 2-alkyl-4-arylmethylaminochinoline, ihre verwendung und daraus hergestellte arzneimittel. | |
DE69013173T2 (de) | Bisarylalkenderivate, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzung, die sie enthalten. | |
ATE25849T1 (de) | Tricyclophosphazen-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel. | |
GEP20063954B (en) | Azabicyclic, azatricyclic and azaspirocyclic derivatives of aminocyclohexane nmda, 5ht3, and neuronal nicotinic receptor antagoni sts | |
DE69104286T2 (de) | Disubstituierte Polymethylenimine, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel. | |
DE68906827D1 (de) | Phenothiazinderivate, deren herstellung und sie enthaltende pharmazeutische zusammensetzungen. | |
ZA934110B (en) | Diacylglycerol nicotinates, process fot their preparation and the pharmaceutical compositions which contain them | |
ATE144986T1 (de) | Aminoacylderivate von gem- diphosphonsauren,verfahren zu deren herstellung und pharmazeutische zubereitungen,die sie enthalten | |
DE69215511D1 (de) | Gem-diphosphonsäure-nitrosocarbamoylderivate, verfahren zu deren herstellung und sie enthaltende pharmazeutische zubereitungen | |
DE3860117D1 (de) | 2,3-dihydro-3-phenyl-benzofuran-2-on-acetamidderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |