PT92663A - Processo para a preparacao de metabolitos diolicos de 7-fenil-1,2,4-triazol(2,3-c)pirimidinas-5-aminas - Google Patents

Processo para a preparacao de metabolitos diolicos de 7-fenil-1,2,4-triazol(2,3-c)pirimidinas-5-aminas

Info

Publication number
PT92663A
PT92663A PT92663A PT9266389A PT92663A PT 92663 A PT92663 A PT 92663A PT 92663 A PT92663 A PT 92663A PT 9266389 A PT9266389 A PT 9266389A PT 92663 A PT92663 A PT 92663A
Authority
PT
Portugal
Prior art keywords
methods
diyal
pyrimidines
triazol
metabolites
Prior art date
Application number
PT92663A
Other languages
English (en)
Other versions
PT92663B (pt
Inventor
Earl George Burton
Christopher Peter Chengelis
Geral Michael Walsh
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of PT92663A publication Critical patent/PT92663A/pt
Publication of PT92663B publication Critical patent/PT92663B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT92663A 1988-12-22 1989-12-21 Processo para a preparacao de metabolitos diolicos de 7-fenil-1,2,4-triazol(2,3-c)pirimidinas-5-aminas PT92663B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/289,068 US4866063A (en) 1988-12-22 1988-12-22 Diol metabolites of 7-phenyl-1,2,4-triazolo[2,3-c]pyrimidines-5-amines

Publications (2)

Publication Number Publication Date
PT92663A true PT92663A (pt) 1990-06-29
PT92663B PT92663B (pt) 1995-09-12

Family

ID=23109911

Family Applications (1)

Application Number Title Priority Date Filing Date
PT92663A PT92663B (pt) 1988-12-22 1989-12-21 Processo para a preparacao de metabolitos diolicos de 7-fenil-1,2,4-triazol(2,3-c)pirimidinas-5-aminas

Country Status (16)

Country Link
US (1) US4866063A (pt)
EP (1) EP0374914B1 (pt)
JP (1) JPH02221276A (pt)
AT (1) ATE104670T1 (pt)
AU (1) AU622963B2 (pt)
CA (1) CA2006354A1 (pt)
DE (1) DE68914808T2 (pt)
DK (1) DK656389A (pt)
ES (1) ES2051980T3 (pt)
FI (1) FI91408C (pt)
IE (1) IE894187L (pt)
IL (1) IL92828A0 (pt)
NO (1) NO170633C (pt)
NZ (1) NZ231937A (pt)
PT (1) PT92663B (pt)
ZA (1) ZA899837B (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5338743A (en) * 1988-06-06 1994-08-16 Fujisawa Pharmaceutical Co., Ltd. New use of the adenosine antagonist

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405780A (en) * 1979-08-08 1983-09-20 G. D. Searle & Co. 8-Substituted 7-phenyl-1,2,4,-triazolo[4,3-c]/[2,3-c]pyrimidines-5-amines and amides
DE3029871C2 (de) * 1979-08-08 1987-01-15 G.D. Searle & Co., Skokie, Ill. 8-(2-Ethoxyethyl)-7-phenyl-1,2,4-triazolo[1,5-c]pyrimidin-5-amin, Verfahren zu dessen Herstellung und pharmazeutische Zubereitung, die diese Verbindung enthält
US4483987A (en) * 1983-06-20 1984-11-20 G. D. Searle & Co. 8-Substituted 7-phenyl-1,2,4-triazolo[2,3-c]pyrimidines-5-amines and amides
FR2567596B1 (fr) * 1984-07-16 1986-12-26 Peugeot Agrafe pour l'assemblage de pieces, telles que des panneaux

Also Published As

Publication number Publication date
EP0374914B1 (en) 1994-04-20
DK656389A (da) 1990-06-23
DE68914808T2 (de) 1994-08-25
IE894187L (en) 1990-06-22
ES2051980T3 (es) 1994-07-01
NO170633C (no) 1992-11-11
ZA899837B (en) 1991-02-27
IL92828A0 (en) 1990-09-17
US4866063A (en) 1989-09-12
FI91408C (fi) 1994-06-27
JPH02221276A (ja) 1990-09-04
FI896173A0 (fi) 1989-12-21
NO895179D0 (no) 1989-12-21
CA2006354A1 (en) 1990-06-22
DE68914808D1 (de) 1994-05-26
AU622963B2 (en) 1992-04-30
PT92663B (pt) 1995-09-12
FI91408B (fi) 1994-03-15
EP0374914A1 (en) 1990-06-27
NO170633B (no) 1992-08-03
DK656389D0 (da) 1989-12-21
ATE104670T1 (de) 1994-05-15
AU4712489A (en) 1990-06-14
NZ231937A (en) 1991-09-25
NO895179L (no) 1990-06-25

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19950508

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19961130