DE68914808D1 - Diolabkömmlinge von 7-Phenyl-1,2,4-triazolo(1,5-c)pyrimidin-5-aminen. - Google Patents

Diolabkömmlinge von 7-Phenyl-1,2,4-triazolo(1,5-c)pyrimidin-5-aminen.

Info

Publication number
DE68914808D1
DE68914808D1 DE68914808T DE68914808T DE68914808D1 DE 68914808 D1 DE68914808 D1 DE 68914808D1 DE 68914808 T DE68914808 T DE 68914808T DE 68914808 T DE68914808 T DE 68914808T DE 68914808 D1 DE68914808 D1 DE 68914808D1
Authority
DE
Germany
Prior art keywords
triazolo
pyrimidin
amines
phenyl
diol derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68914808T
Other languages
English (en)
Other versions
DE68914808T2 (de
Inventor
Earl George Burton
Christopher Peter Chengelis
Gerald Michael Walsh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Application granted granted Critical
Publication of DE68914808D1 publication Critical patent/DE68914808D1/de
Publication of DE68914808T2 publication Critical patent/DE68914808T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE68914808T 1988-12-22 1989-12-21 Diolabkömmlinge von 7-Phenyl-1,2,4-triazolo(1,5-c)pyrimidin-5-aminen. Expired - Fee Related DE68914808T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/289,068 US4866063A (en) 1988-12-22 1988-12-22 Diol metabolites of 7-phenyl-1,2,4-triazolo[2,3-c]pyrimidines-5-amines

Publications (2)

Publication Number Publication Date
DE68914808D1 true DE68914808D1 (de) 1994-05-26
DE68914808T2 DE68914808T2 (de) 1994-08-25

Family

ID=23109911

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68914808T Expired - Fee Related DE68914808T2 (de) 1988-12-22 1989-12-21 Diolabkömmlinge von 7-Phenyl-1,2,4-triazolo(1,5-c)pyrimidin-5-aminen.

Country Status (16)

Country Link
US (1) US4866063A (de)
EP (1) EP0374914B1 (de)
JP (1) JPH02221276A (de)
AT (1) ATE104670T1 (de)
AU (1) AU622963B2 (de)
CA (1) CA2006354A1 (de)
DE (1) DE68914808T2 (de)
DK (1) DK656389A (de)
ES (1) ES2051980T3 (de)
FI (1) FI91408C (de)
IE (1) IE894187L (de)
IL (1) IL92828A0 (de)
NO (1) NO170633C (de)
NZ (1) NZ231937A (de)
PT (1) PT92663B (de)
ZA (1) ZA899837B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5338743A (en) * 1988-06-06 1994-08-16 Fujisawa Pharmaceutical Co., Ltd. New use of the adenosine antagonist

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405780A (en) * 1979-08-08 1983-09-20 G. D. Searle & Co. 8-Substituted 7-phenyl-1,2,4,-triazolo[4,3-c]/[2,3-c]pyrimidines-5-amines and amides
DE3029871C2 (de) * 1979-08-08 1987-01-15 G.D. Searle & Co., Skokie, Ill. 8-(2-Ethoxyethyl)-7-phenyl-1,2,4-triazolo[1,5-c]pyrimidin-5-amin, Verfahren zu dessen Herstellung und pharmazeutische Zubereitung, die diese Verbindung enthält
US4483987A (en) * 1983-06-20 1984-11-20 G. D. Searle & Co. 8-Substituted 7-phenyl-1,2,4-triazolo[2,3-c]pyrimidines-5-amines and amides
FR2567596B1 (fr) * 1984-07-16 1986-12-26 Peugeot Agrafe pour l'assemblage de pieces, telles que des panneaux

Also Published As

Publication number Publication date
EP0374914B1 (de) 1994-04-20
DK656389A (da) 1990-06-23
DE68914808T2 (de) 1994-08-25
IE894187L (en) 1990-06-22
ES2051980T3 (es) 1994-07-01
NO170633C (no) 1992-11-11
ZA899837B (en) 1991-02-27
IL92828A0 (en) 1990-09-17
US4866063A (en) 1989-09-12
FI91408C (fi) 1994-06-27
JPH02221276A (ja) 1990-09-04
FI896173A0 (fi) 1989-12-21
NO895179D0 (no) 1989-12-21
CA2006354A1 (en) 1990-06-22
PT92663A (pt) 1990-06-29
AU622963B2 (en) 1992-04-30
PT92663B (pt) 1995-09-12
FI91408B (fi) 1994-03-15
EP0374914A1 (de) 1990-06-27
NO170633B (no) 1992-08-03
DK656389D0 (da) 1989-12-21
ATE104670T1 (de) 1994-05-15
AU4712489A (en) 1990-06-14
NZ231937A (en) 1991-09-25
NO895179L (no) 1990-06-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee