PT90241A - Metodo para a preparacao de polipeptidos estabilizados pelas substituicoes de ligacoes de hidrogenio covalentes - Google Patents

Metodo para a preparacao de polipeptidos estabilizados pelas substituicoes de ligacoes de hidrogenio covalentes

Info

Publication number
PT90241A
PT90241A PT9024189A PT9024189A PT90241A PT 90241 A PT90241 A PT 90241A PT 9024189 A PT9024189 A PT 9024189A PT 9024189 A PT9024189 A PT 9024189A PT 90241 A PT90241 A PT 90241A
Authority
PT
Portugal
Prior art keywords
ligacons
substitutions
preparation
covalent hydrogen
polypeptides
Prior art date
Application number
PT9024189A
Other languages
English (en)
Inventor
Arnold C Satterthwait Jr
Thomas Arrhenius
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Publication of PT90241A publication Critical patent/PT90241A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
PT9024189A 1988-04-08 1989-04-10 Metodo para a preparacao de polipeptidos estabilizados pelas substituicoes de ligacoes de hidrogenio covalentes PT90241A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17916088A 1988-04-08 1988-04-08

Publications (1)

Publication Number Publication Date
PT90241A true PT90241A (pt) 1989-11-10

Family

ID=22655472

Family Applications (1)

Application Number Title Priority Date Filing Date
PT9024189A PT90241A (pt) 1988-04-08 1989-04-10 Metodo para a preparacao de polipeptidos estabilizados pelas substituicoes de ligacoes de hidrogenio covalentes

Country Status (6)

Country Link
EP (1) EP0336779A3 (pt)
JP (1) JPH03504496A (pt)
AU (1) AU3534989A (pt)
DK (1) DK241190A (pt)
PT (1) PT90241A (pt)
WO (1) WO1989009783A1 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364851A (en) * 1991-06-14 1994-11-15 International Synthecon, Llc Conformationally restricted biologically active peptides, methods for their production and uses thereof
US5541116A (en) * 1991-09-30 1996-07-30 B.R.A.H.M.S. Diagnostica Gmbh Method for the stabilization of endogenous, physiologically active peptides
US6117974A (en) * 1991-10-02 2000-09-12 Peptor Limited Libraries of backbone-cyclized peptidomimetics
GB2288601A (en) * 1994-04-12 1995-10-25 Peter James Wallace Midgley Intra-molecular cross-linking of helical polypeptide chains
US6407059B1 (en) 1994-06-08 2002-06-18 Peptor Limited Conformationally constrained backbone cyclized peptide analogs
IL109943A (en) 1994-06-08 2006-08-01 Develogen Israel Ltd Conformationally constrained backbone cyclized peptide analogs
US6051554A (en) * 1995-06-07 2000-04-18 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
US5770687A (en) * 1995-06-07 1998-06-23 Peptor Limited Comformationally constrained backbone cyclized somatostatin analogs
US6251939B1 (en) * 1995-06-07 2001-06-26 Promega Biosciences, Inc. Carbamate-based cationic lipids
US6841533B1 (en) 1995-12-07 2005-01-11 Peptor Limited Conformationally constrained backbone cyclized interleukin-6 antagonists
US6355613B1 (en) 1996-07-31 2002-03-12 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
CA2309575A1 (en) 2000-05-26 2001-11-26 James E. Guillet Internally cross-linked macromolecules
US9243040B2 (en) 2010-11-30 2016-01-26 The Board Of Trustees Of The University Of Illinois Stable helical ionic polypeptides
CN113727991A (zh) * 2019-05-14 2021-11-30 一丸自然美健有限公司 Ras抑制肽

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1164239B (it) * 1983-05-25 1987-04-08 Anic Spa Un retro-inverso analogo del decapeptide (5-14)dell'angiotensinogeno equino inibitore specifico della renina con elevata resistenza all'idrolisi enzimatica
IT1178786B (it) * 1984-12-21 1987-09-16 Assorenti Analoghi retro-inverso parzialmente modificati della neurotensina
US4803261A (en) * 1986-06-27 1989-02-07 The Administrators Of The Tulane Educational Fund Method for synthesizing a peptide containing a non-peptide

Also Published As

Publication number Publication date
WO1989009783A1 (en) 1989-10-19
EP0336779A2 (en) 1989-10-11
DK241190A (da) 1990-12-07
JPH03504496A (ja) 1991-10-03
DK241190D0 (da) 1990-10-05
AU3534989A (en) 1989-11-03
EP0336779A3 (en) 1991-08-21

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Legal Events

Date Code Title Description
FC3A Refusal

Effective date: 19941107