DK241190A - Polypeptider stabiliseret med kovalente hydrogenbindingserstatninger - Google Patents

Polypeptider stabiliseret med kovalente hydrogenbindingserstatninger Download PDF

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Publication number
DK241190A
DK241190A DK241190A DK241190A DK241190A DK 241190 A DK241190 A DK 241190A DK 241190 A DK241190 A DK 241190A DK 241190 A DK241190 A DK 241190A DK 241190 A DK241190 A DK 241190A
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DK
Denmark
Prior art keywords
hydrogen bond
bond replacement
covalent hydrogen
polypeptides
stabilized
Prior art date
Application number
DK241190A
Other languages
English (en)
Other versions
DK241190D0 (da
Inventor
Jr Arnold C Satterthwait
Thomas Arrhenius
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Publication of DK241190D0 publication Critical patent/DK241190D0/da
Publication of DK241190A publication Critical patent/DK241190A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
DK241190A 1988-04-08 1990-10-05 Polypeptider stabiliseret med kovalente hydrogenbindingserstatninger DK241190A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17916088A 1988-04-08 1988-04-08
PCT/US1989/001452 WO1989009783A1 (en) 1988-04-08 1989-04-07 Polypeptides stabilized by covalent hydrogen bond replacements

Publications (2)

Publication Number Publication Date
DK241190D0 DK241190D0 (da) 1990-10-05
DK241190A true DK241190A (da) 1990-12-07

Family

ID=22655472

Family Applications (1)

Application Number Title Priority Date Filing Date
DK241190A DK241190A (da) 1988-04-08 1990-10-05 Polypeptider stabiliseret med kovalente hydrogenbindingserstatninger

Country Status (6)

Country Link
EP (1) EP0336779A3 (da)
JP (1) JPH03504496A (da)
AU (1) AU3534989A (da)
DK (1) DK241190A (da)
PT (1) PT90241A (da)
WO (1) WO1989009783A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364851A (en) * 1991-06-14 1994-11-15 International Synthecon, Llc Conformationally restricted biologically active peptides, methods for their production and uses thereof
US5541116A (en) * 1991-09-30 1996-07-30 B.R.A.H.M.S. Diagnostica Gmbh Method for the stabilization of endogenous, physiologically active peptides
US6117974A (en) * 1991-10-02 2000-09-12 Peptor Limited Libraries of backbone-cyclized peptidomimetics
GB2288601A (en) * 1994-04-12 1995-10-25 Peter James Wallace Midgley Intra-molecular cross-linking of helical polypeptide chains
US6407059B1 (en) 1994-06-08 2002-06-18 Peptor Limited Conformationally constrained backbone cyclized peptide analogs
IL109943A (en) 1994-06-08 2006-08-01 Develogen Israel Ltd Conformationally constrained backbone cyclized peptide analogs
US6051554A (en) * 1995-06-07 2000-04-18 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
US5770687A (en) * 1995-06-07 1998-06-23 Peptor Limited Comformationally constrained backbone cyclized somatostatin analogs
US6251939B1 (en) * 1995-06-07 2001-06-26 Promega Biosciences, Inc. Carbamate-based cationic lipids
US6841533B1 (en) 1995-12-07 2005-01-11 Peptor Limited Conformationally constrained backbone cyclized interleukin-6 antagonists
US6355613B1 (en) 1996-07-31 2002-03-12 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
CA2309575A1 (en) 2000-05-26 2001-11-26 James E. Guillet Internally cross-linked macromolecules
US9243040B2 (en) 2010-11-30 2016-01-26 The Board Of Trustees Of The University Of Illinois Stable helical ionic polypeptides
CN113727991A (zh) * 2019-05-14 2021-11-30 一丸自然美健有限公司 Ras抑制肽

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1164239B (it) * 1983-05-25 1987-04-08 Anic Spa Un retro-inverso analogo del decapeptide (5-14)dell'angiotensinogeno equino inibitore specifico della renina con elevata resistenza all'idrolisi enzimatica
IT1178786B (it) * 1984-12-21 1987-09-16 Assorenti Analoghi retro-inverso parzialmente modificati della neurotensina
US4803261A (en) * 1986-06-27 1989-02-07 The Administrators Of The Tulane Educational Fund Method for synthesizing a peptide containing a non-peptide

Also Published As

Publication number Publication date
WO1989009783A1 (en) 1989-10-19
EP0336779A2 (en) 1989-10-11
JPH03504496A (ja) 1991-10-03
DK241190D0 (da) 1990-10-05
PT90241A (pt) 1989-11-10
AU3534989A (en) 1989-11-03
EP0336779A3 (en) 1991-08-21

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment