PT892802E - Espiro¬ciclopent(b)indol-piperidinas| e intermediarios n-fenil-hidrazina para a sua preparacao sendo ambos inibidores da acetilcolinesterase e da mao - Google Patents

Espiro¬ciclopent(b)indol-piperidinas| e intermediarios n-fenil-hidrazina para a sua preparacao sendo ambos inibidores da acetilcolinesterase e da mao

Info

Publication number
PT892802E
PT892802E PT97908068T PT97908068T PT892802E PT 892802 E PT892802 E PT 892802E PT 97908068 T PT97908068 T PT 97908068T PT 97908068 T PT97908068 T PT 97908068T PT 892802 E PT892802 E PT 892802E
Authority
PT
Portugal
Prior art keywords
piperidinas
ciclopent
acetilcolinesterase
espiro
intermediaries
Prior art date
Application number
PT97908068T
Other languages
English (en)
Inventor
Gerard J O'malley
Mark G Palermo
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of PT892802E publication Critical patent/PT892802E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
PT97908068T 1996-04-10 1997-03-10 Espiro¬ciclopent(b)indol-piperidinas| e intermediarios n-fenil-hidrazina para a sua preparacao sendo ambos inibidores da acetilcolinesterase e da mao PT892802E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63064196A 1996-04-10 1996-04-10

Publications (1)

Publication Number Publication Date
PT892802E true PT892802E (pt) 2004-03-31

Family

ID=24527997

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97908068T PT892802E (pt) 1996-04-10 1997-03-10 Espiro¬ciclopent(b)indol-piperidinas| e intermediarios n-fenil-hidrazina para a sua preparacao sendo ambos inibidores da acetilcolinesterase e da mao

Country Status (18)

Country Link
EP (1) EP0892802B1 (pt)
JP (1) JP3615225B2 (pt)
KR (1) KR100270145B1 (pt)
CN (1) CN1233249A (pt)
AR (1) AR006553A1 (pt)
AT (1) ATE252581T1 (pt)
AU (1) AU708124B2 (pt)
BR (1) BR9708563A (pt)
CA (1) CA2251545C (pt)
DE (1) DE69725713T2 (pt)
DK (1) DK0892802T3 (pt)
ES (1) ES2207718T3 (pt)
HU (1) HUP9902755A3 (pt)
IL (1) IL126003A0 (pt)
NO (1) NO984739L (pt)
PT (1) PT892802E (pt)
WO (1) WO1997037992A2 (pt)
ZA (1) ZA972984B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1572299A (zh) 1998-09-30 2005-02-02 武田药品工业株式会社 改善膀胱排泄能力的药物
CA2788656A1 (en) 2010-02-16 2011-08-25 Pfizer Inc. (r)-4-((4-((4-(tetrahydrofuran-3-yloxy)benzo[d]isoxazol-3-yloxy)methyl)piperidin-1-yl)methyl)tetrahydro-2h-pyran-4-ol, a partial agonist of 5-ht4 receptors
AU2016353446B2 (en) 2015-11-12 2022-05-19 Afasci, Inc. Ion channel inhibitory compounds, pharmaceutical formulations and uses
AR116020A1 (es) 2018-09-03 2021-03-25 Bayer Ag COMPUESTOS DE 3,9-DIAZAESPIRO[5.5]UNDECANO COMO INHIBIDORES DE GGTasa I Y SU USO PARA EL TRATAMIENTO DE ENFERMEDADES HIPERPROLIFERATIVAS
WO2020048827A1 (en) 2018-09-03 2020-03-12 Bayer Aktiengesellschaft 1, 3, 9-triazaspiro[5.5] undecan-2-one compounds
WO2020048828A1 (en) 2018-09-03 2020-03-12 Bayer Pharma Aktiengesellschaft 5-heteroaryl-3,9-diazaspiro[5.5]undecane compounds

Also Published As

Publication number Publication date
EP0892802B1 (en) 2003-10-22
CA2251545C (en) 2002-01-08
DK0892802T3 (da) 2003-12-01
NO984739L (no) 1998-12-09
DE69725713D1 (de) 2003-11-27
AU1990997A (en) 1997-10-29
NO984739D0 (no) 1998-10-09
ATE252581T1 (de) 2003-11-15
HUP9902755A3 (en) 2000-05-29
IL126003A0 (en) 1999-04-11
WO1997037992A2 (en) 1997-10-16
KR20000005328A (ko) 2000-01-25
ZA972984B (en) 1997-11-03
JP3615225B2 (ja) 2005-02-02
EP0892802A1 (en) 1999-01-27
CN1233249A (zh) 1999-10-27
JP2002509520A (ja) 2002-03-26
BR9708563A (pt) 1999-08-03
AR006553A1 (es) 1999-09-08
HUP9902755A2 (hu) 2000-03-28
CA2251545A1 (en) 1997-10-16
AU708124B2 (en) 1999-07-29
DE69725713T2 (de) 2004-05-13
KR100270145B1 (ko) 2000-11-01
ES2207718T3 (es) 2004-06-01

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