IL126003A0 - Spiro [cyclopent [b] indole-piperidines] and n-[phenyl-hydrazon intermediates for their preparation both being acetyl cholinesterase and mao inhibitors - Google Patents
Spiro [cyclopent [b] indole-piperidines] and n-[phenyl-hydrazon intermediates for their preparation both being acetyl cholinesterase and mao inhibitorsInfo
- Publication number
- IL126003A0 IL126003A0 IL12600397A IL12600397A IL126003A0 IL 126003 A0 IL126003 A0 IL 126003A0 IL 12600397 A IL12600397 A IL 12600397A IL 12600397 A IL12600397 A IL 12600397A IL 126003 A0 IL126003 A0 IL 126003A0
- Authority
- IL
- Israel
- Prior art keywords
- hydrazon
- cyclopent
- piperidines
- spiro
- indole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Psychiatry (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63064196A | 1996-04-10 | 1996-04-10 | |
| PCT/US1997/003864 WO1997037992A2 (en) | 1996-04-10 | 1997-03-10 | Spiro[cyclopent[b]indole-piperidines] and n-phenyl-hydrazon intermediates for their preparation, both being acetylcholinesterase and mao inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL126003A0 true IL126003A0 (en) | 1999-04-11 |
Family
ID=24527997
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12600397A IL126003A0 (en) | 1996-04-10 | 1997-03-01 | Spiro [cyclopent [b] indole-piperidines] and n-[phenyl-hydrazon intermediates for their preparation both being acetyl cholinesterase and mao inhibitors |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0892802B1 (pt) |
| JP (1) | JP3615225B2 (pt) |
| KR (1) | KR100270145B1 (pt) |
| CN (1) | CN1233249A (pt) |
| AR (1) | AR006553A1 (pt) |
| AT (1) | ATE252581T1 (pt) |
| AU (1) | AU708124B2 (pt) |
| BR (1) | BR9708563A (pt) |
| CA (1) | CA2251545C (pt) |
| DE (1) | DE69725713T2 (pt) |
| DK (1) | DK0892802T3 (pt) |
| ES (1) | ES2207718T3 (pt) |
| HU (1) | HUP9902755A3 (pt) |
| IL (1) | IL126003A0 (pt) |
| NO (1) | NO984739L (pt) |
| PT (1) | PT892802E (pt) |
| WO (1) | WO1997037992A2 (pt) |
| ZA (1) | ZA972984B (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1572299A (zh) | 1998-09-30 | 2005-02-02 | 武田药品工业株式会社 | 改善膀胱排泄能力的药物 |
| CA2788656A1 (en) | 2010-02-16 | 2011-08-25 | Pfizer Inc. | (r)-4-((4-((4-(tetrahydrofuran-3-yloxy)benzo[d]isoxazol-3-yloxy)methyl)piperidin-1-yl)methyl)tetrahydro-2h-pyran-4-ol, a partial agonist of 5-ht4 receptors |
| AU2016353446B2 (en) | 2015-11-12 | 2022-05-19 | Afasci, Inc. | Ion channel inhibitory compounds, pharmaceutical formulations and uses |
| AR116020A1 (es) | 2018-09-03 | 2021-03-25 | Bayer Ag | COMPUESTOS DE 3,9-DIAZAESPIRO[5.5]UNDECANO COMO INHIBIDORES DE GGTasa I Y SU USO PARA EL TRATAMIENTO DE ENFERMEDADES HIPERPROLIFERATIVAS |
| WO2020048827A1 (en) | 2018-09-03 | 2020-03-12 | Bayer Aktiengesellschaft | 1, 3, 9-triazaspiro[5.5] undecan-2-one compounds |
| WO2020048828A1 (en) | 2018-09-03 | 2020-03-12 | Bayer Pharma Aktiengesellschaft | 5-heteroaryl-3,9-diazaspiro[5.5]undecane compounds |
-
1997
- 1997-03-01 IL IL12600397A patent/IL126003A0/xx unknown
- 1997-03-10 JP JP53619797A patent/JP3615225B2/ja not_active Expired - Fee Related
- 1997-03-10 AT AT97908068T patent/ATE252581T1/de not_active IP Right Cessation
- 1997-03-10 CN CN97193690A patent/CN1233249A/zh active Pending
- 1997-03-10 BR BR9708563A patent/BR9708563A/pt not_active IP Right Cessation
- 1997-03-10 KR KR1019980708047A patent/KR100270145B1/ko not_active IP Right Cessation
- 1997-03-10 AU AU19909/97A patent/AU708124B2/en not_active Ceased
- 1997-03-10 CA CA002251545A patent/CA2251545C/en not_active Expired - Fee Related
- 1997-03-10 WO PCT/US1997/003864 patent/WO1997037992A2/en active IP Right Grant
- 1997-03-10 HU HU9902755A patent/HUP9902755A3/hu unknown
- 1997-03-10 PT PT97908068T patent/PT892802E/pt unknown
- 1997-03-10 EP EP97908068A patent/EP0892802B1/en not_active Expired - Lifetime
- 1997-03-10 DE DE69725713T patent/DE69725713T2/de not_active Expired - Fee Related
- 1997-03-10 DK DK97908068T patent/DK0892802T3/da active
- 1997-03-10 ES ES97908068T patent/ES2207718T3/es not_active Expired - Lifetime
- 1997-04-08 AR ARP970101376A patent/AR006553A1/es not_active Application Discontinuation
- 1997-04-08 ZA ZA9702984A patent/ZA972984B/xx unknown
-
1998
- 1998-10-09 NO NO984739A patent/NO984739L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0892802B1 (en) | 2003-10-22 |
| CA2251545C (en) | 2002-01-08 |
| PT892802E (pt) | 2004-03-31 |
| DK0892802T3 (da) | 2003-12-01 |
| NO984739L (no) | 1998-12-09 |
| DE69725713D1 (de) | 2003-11-27 |
| AU1990997A (en) | 1997-10-29 |
| NO984739D0 (no) | 1998-10-09 |
| ATE252581T1 (de) | 2003-11-15 |
| HUP9902755A3 (en) | 2000-05-29 |
| WO1997037992A2 (en) | 1997-10-16 |
| KR20000005328A (ko) | 2000-01-25 |
| ZA972984B (en) | 1997-11-03 |
| JP3615225B2 (ja) | 2005-02-02 |
| EP0892802A1 (en) | 1999-01-27 |
| CN1233249A (zh) | 1999-10-27 |
| JP2002509520A (ja) | 2002-03-26 |
| BR9708563A (pt) | 1999-08-03 |
| AR006553A1 (es) | 1999-09-08 |
| HUP9902755A2 (hu) | 2000-03-28 |
| CA2251545A1 (en) | 1997-10-16 |
| AU708124B2 (en) | 1999-07-29 |
| DE69725713T2 (de) | 2004-05-13 |
| KR100270145B1 (ko) | 2000-11-01 |
| ES2207718T3 (es) | 2004-06-01 |
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