PT88556A - Stable genomic integration and expression of a foreign coding sequence in yeast - Google Patents

Stable genomic integration and expression of a foreign coding sequence in yeast

Info

Publication number
PT88556A
PT88556A PT88556A PT8855688A PT88556A PT 88556 A PT88556 A PT 88556A PT 88556 A PT88556 A PT 88556A PT 8855688 A PT8855688 A PT 8855688A PT 88556 A PT88556 A PT 88556A
Authority
PT
Portugal
Prior art keywords
yeast
expression
coding sequence
genomic integration
stable genomic
Prior art date
Application number
PT88556A
Other languages
English (en)
Other versions
PT88556B (pt
Inventor
Jef Daniel Boeke
Marianne G Dewerchin
Eric J J Jacobs
Original Assignee
Smith Kline Rit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline Rit filed Critical Smith Kline Rit
Publication of PT88556A publication Critical patent/PT88556A/pt
Publication of PT88556B publication Critical patent/PT88556B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PT88556A 1987-09-28 1988-09-20 Processo de integracao genomica estavel e de expressao de uma sequencia de cadificacao estranha, em leveduras PT88556B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10146387A 1987-09-28 1987-09-28

Publications (2)

Publication Number Publication Date
PT88556A true PT88556A (pt) 1988-10-01
PT88556B PT88556B (pt) 1992-11-30

Family

ID=22284790

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88556A PT88556B (pt) 1987-09-28 1988-09-20 Processo de integracao genomica estavel e de expressao de uma sequencia de cadificacao estranha, em leveduras

Country Status (6)

Country Link
EP (1) EP0310586A1 (pt)
JP (1) JPH01157393A (pt)
AU (1) AU2246188A (pt)
DK (1) DK531788A (pt)
PT (1) PT88556B (pt)
ZA (1) ZA887194B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991000920A2 (en) * 1989-07-07 1991-01-24 Unilever N.V. Process for preparing a protein by a fungus transformed by multicopy integration of an expression vector
FR2670502B1 (fr) * 1990-12-13 1994-09-16 Eurolysine Cassette d'integration "multisite" dans le genome d'une levure, levure transformee et procede de preparation d'un produit d'interet par une levure ainsi transformee.
DK0587791T3 (da) * 1991-05-31 2004-07-26 Genentech Inc Forstærkelse af ekspression ved hjælp af gentargeting i endogene retroviruslignende sekvenser
EP0592358B1 (en) * 1992-09-04 2000-10-11 Novartis AG Process for the production of protease inhibitors
TW282490B (pt) * 1992-12-15 1996-08-01 Ciba Geigy Ag

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4670388A (en) * 1982-12-30 1987-06-02 Carnegie Institution Of Washington Method of incorporating DNA into genome of drosophila
GB8424757D0 (en) * 1984-10-01 1984-11-07 Pasteur Institut Retroviral vector
CA1293460C (en) * 1985-10-07 1991-12-24 Brian Lee Sauer Site-specific recombination of dna in yeast
WO1988001646A1 (en) * 1986-08-26 1988-03-10 Allelix Inc. Universal system for transposon mutagenesis

Also Published As

Publication number Publication date
EP0310586A1 (en) 1989-04-05
ZA887194B (en) 1989-07-26
DK531788A (da) 1989-03-29
DK531788D0 (da) 1988-09-23
AU2246188A (en) 1989-04-13
PT88556B (pt) 1992-11-30
JPH01157393A (ja) 1989-06-20

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920521

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19931130