PT87560A - Linear and cyclic analogs of alpha-msh fragments with extraordinary potency - Google Patents

Linear and cyclic analogs of alpha-msh fragments with extraordinary potency

Info

Publication number
PT87560A
PT87560A PT87560A PT8756088A PT87560A PT 87560 A PT87560 A PT 87560A PT 87560 A PT87560 A PT 87560A PT 8756088 A PT8756088 A PT 8756088A PT 87560 A PT87560 A PT 87560A
Authority
PT
Portugal
Prior art keywords
linear
alpha
cyclic analogs
extraordinary potency
msh fragments
Prior art date
Application number
PT87560A
Other languages
English (en)
Other versions
PT87560B (pt
Inventor
Victor J Hruby
Fahad A Al-Obeidi
Mac E Hadley
Original Assignee
University Patents Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Patents Inc filed Critical University Patents Inc
Publication of PT87560A publication Critical patent/PT87560A/pt
Publication of PT87560B publication Critical patent/PT87560B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/68—Melanocyte-stimulating hormone [MSH]
    • C07K14/685—Alpha-melanotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Cosmetics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Steroid Compounds (AREA)
PT87560A 1987-05-22 1988-05-23 Processo de preparacao de analagos lineares e ciclicos de fragmentos alfa-msh com potencia extraordinaria PT87560B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5322987A 1987-05-22 1987-05-22
CA000578920A CA1340107C (en) 1987-05-22 1988-09-30 Linear and cyclic analoques of alpha-msh fragments with extraordinary potency

Publications (2)

Publication Number Publication Date
PT87560A true PT87560A (pt) 1989-05-31
PT87560B PT87560B (pt) 1992-09-30

Family

ID=25672150

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87560A PT87560B (pt) 1987-05-22 1988-05-23 Processo de preparacao de analagos lineares e ciclicos de fragmentos alfa-msh com potencia extraordinaria

Country Status (11)

Country Link
EP (1) EP0292291B1 (pt)
JP (1) JPH0826077B2 (pt)
CN (1) CN1031242C (pt)
AT (1) ATE109793T1 (pt)
CA (1) CA1340107C (pt)
DE (1) DE3851002T2 (pt)
DK (1) DK172760B1 (pt)
FI (1) FI882380A (pt)
IE (1) IE64903B1 (pt)
PH (1) PH25819A (pt)
PT (1) PT87560B (pt)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5674839A (en) * 1987-05-22 1997-10-07 Competitive Technologies, Inc. Cyclic analogs of alpha-MSH fragments
US5683981A (en) * 1987-05-22 1997-11-04 Competitive Technologies, Inc. Cyclic bridged analogs of α-MSH and methods thereof
EP0389950A1 (en) * 1989-03-23 1990-10-03 Lion Corporation Melanocyte-stimulating hormone inhibitor and external preparation containing the same
US5071583A (en) * 1990-08-14 1991-12-10 Steve Martell Soap bar having a fifth finger gripping member
GB9102450D0 (en) * 1991-02-05 1991-03-20 Sandoz Ltd Improvements in or relating to organic compounds
US5364851A (en) * 1991-06-14 1994-11-15 International Synthecon, Llc Conformationally restricted biologically active peptides, methods for their production and uses thereof
US6100048A (en) * 1992-04-10 2000-08-08 Oregon Health Sciences University Methods and reagents for discovering and using mammalian melanocortin receptor agonists and antagonists to modulate feeding behavior in animals
FR2691465B1 (fr) * 1992-05-25 1995-08-11 Pf Medicament Complexes comprenant au moins un peptide derive de l'alpha msh, peptide, microsphere, medicament et composition galenique les comprenant.
WO1994022460A1 (en) * 1993-04-05 1994-10-13 University Patents, Inc. Diagnosis and treatment of erectile dysfunction
FR2710340B1 (fr) * 1993-09-22 1995-12-15 D Hinterland Lucien Dussourd Dérivés peptidiques de l'alpha-MSH et leur application .
US5420109A (en) 1993-11-12 1995-05-30 Houghten Pharmaceuticals, Inc. Cytokine restraining agents
US5726156A (en) * 1995-03-06 1998-03-10 Trega Biosciences, Inc. Cytokine regulatory agents and methods of use in pathologies and conditions associated with altered cytokine levels
US5786332A (en) * 1995-03-06 1998-07-28 Trega Biosciences, Inc. Cytokine restraining agents and methods of use in pathologies and conditions associated with altered cytokine levels
US6716810B1 (en) * 1998-12-09 2004-04-06 Eleanor Roosevelt Institute Composition and method for regulation of body weight and associated conditions
CA2368431C (en) 1999-03-29 2006-01-24 The Procter & Gamble Company Melanocortin receptor ligands
TW200716979A (en) * 1999-06-29 2007-05-01 Univ New York Screening methods for compounds that affect melanogenesis
DE10228837B4 (de) * 2002-06-27 2016-01-07 Elfriede Rauch Hautkosmetische Zusammensetzung und Verwendung der Zusammensetzung als Hautbräunungsmittel
AU2004275928B2 (en) 2003-09-30 2010-03-11 Novo Nordisk A/S Melanocortin receptor agonists
EP2939686A1 (en) * 2004-10-08 2015-11-04 Clinuvel Pharmaceuticals Limited Compositions and methods for inducing melanogenesis in a subject
CN100355776C (zh) * 2005-06-20 2007-12-19 中国人民解放军第二军医大学 一种新型α－黑素细胞刺激素类似物及其用途
CN101528250A (zh) 2005-07-08 2009-09-09 研究及应用科学协会股份有限公司 黑皮质素受体的配体
DK2957292T3 (en) 2008-03-27 2018-01-22 Clinuvel Pharmaceuticals Ltd VITILIGOTERAPHY
NZ590254A (en) 2008-06-09 2012-07-27 Palatin Technologies Inc Melanocortin receptor-specific cyclic peptides for treatment of sexual dysfunction
WO2010022249A2 (en) 2008-08-20 2010-02-25 Ensemble Discovery Corporation Macrocyclic compounds for inhibition of tumor necrosis factor alpha
UY32690A (es) 2009-06-08 2011-01-31 Astrazeneca Ab Péptidos específicos para receptores de melanocortina
EP2504351A4 (en) 2009-11-23 2013-10-30 Palatin Technologies Inc MELANOCORTIN-1 RECEPTOR-SPECIFIC LINEAR PEPTIDE
CN102725305B (zh) 2009-11-23 2016-08-24 帕拉丁科技公司 黑皮质素-1受体特异性环肽
CN102816211B (zh) * 2012-09-10 2014-07-23 南京工业大学 一种制备美那诺坦的方法
EP2970388B1 (en) * 2013-03-15 2018-07-25 Rhythm Pharmaceuticals, Inc. Peptide compositions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US448539A (en) 1891-03-17 Cornelius s morris
US4457864A (en) * 1981-10-23 1984-07-03 University Patents, Inc. Synthetic analogues of α-melanotropin
US4485039A (en) * 1982-06-11 1984-11-27 University Patents, Inc. Synthetic analogues of α-melanotropin

Also Published As

Publication number Publication date
DK277788A (da) 1988-11-23
DE3851002D1 (de) 1994-09-15
IE881537L (en) 1988-11-22
EP0292291A3 (en) 1990-05-02
PT87560B (pt) 1992-09-30
CN1032795A (zh) 1989-05-10
AU1650688A (en) 1988-11-24
EP0292291B1 (en) 1994-08-10
EP0292291A2 (en) 1988-11-23
DK277788D0 (da) 1988-05-20
PH25819A (en) 1991-11-05
FI882380A (fi) 1988-11-23
FI882380A0 (fi) 1988-05-20
AU618733B2 (en) 1992-01-09
JPH0826077B2 (ja) 1996-03-13
JPS6470499A (en) 1989-03-15
CA1340107C (en) 1998-10-27
CN1031242C (zh) 1996-03-13
DK172760B1 (da) 1999-06-28
ATE109793T1 (de) 1994-08-15
IE64903B1 (en) 1995-09-20
DE3851002T2 (de) 1995-02-02

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920310

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19970930