PT871612E - Isoindolonas fundidas como inibidores de proteina cinase c - Google Patents
Isoindolonas fundidas como inibidores de proteina cinase cInfo
- Publication number
- PT871612E PT871612E PT96943735T PT96943735T PT871612E PT 871612 E PT871612 E PT 871612E PT 96943735 T PT96943735 T PT 96943735T PT 96943735 T PT96943735 T PT 96943735T PT 871612 E PT871612 E PT 871612E
- Authority
- PT
- Portugal
- Prior art keywords
- isoindolones
- cinase
- covered
- protein inhibitors
- fused
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US873395P | 1995-12-11 | 1995-12-11 | |
US08/761,951 US5808060A (en) | 1995-12-11 | 1996-12-09 | Fused isoindolones |
Publications (1)
Publication Number | Publication Date |
---|---|
PT871612E true PT871612E (pt) | 2003-06-30 |
Family
ID=26678542
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT96943735T PT871612E (pt) | 1995-12-11 | 1996-12-11 | Isoindolonas fundidas como inibidores de proteina cinase c |
Country Status (15)
Country | Link |
---|---|
US (1) | US5808060A (pt) |
EP (1) | EP0871612B1 (pt) |
KR (1) | KR100534528B1 (pt) |
CN (1) | CN1139573C (pt) |
AT (1) | ATE234284T1 (pt) |
AU (1) | AU701412B2 (pt) |
BR (1) | BR9611947A (pt) |
CA (1) | CA2239282C (pt) |
DE (1) | DE69626680T2 (pt) |
DK (1) | DK0871612T3 (pt) |
ES (1) | ES2195033T3 (pt) |
HK (1) | HK1016599A1 (pt) |
NZ (1) | NZ325073A (pt) |
PT (1) | PT871612E (pt) |
WO (1) | WO1997021677A1 (pt) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6127401A (en) * | 1998-06-05 | 2000-10-03 | Cephalon, Inc. | Bridged indenopyrrolocarbazoles |
US6841567B1 (en) * | 1999-02-12 | 2005-01-11 | Cephalon, Inc. | Cyclic substituted fused pyrrolocarbazoles and isoindolones |
US6399780B1 (en) * | 1999-08-20 | 2002-06-04 | Cephalon, Inc. | Isomeric fused pyrrolocarbazoles and isoindolones |
US6630500B2 (en) * | 2000-08-25 | 2003-10-07 | Cephalon, Inc. | Selected fused pyrrolocarbazoles |
US7285287B2 (en) * | 2002-11-14 | 2007-10-23 | Synecor, Llc | Carbon dioxide-assisted methods of providing biocompatible intraluminal prostheses |
US20040098106A1 (en) * | 2002-11-14 | 2004-05-20 | Williams Michael S. | Intraluminal prostheses and carbon dioxide-assisted methods of impregnating same with pharmacological agents |
US6932930B2 (en) * | 2003-03-10 | 2005-08-23 | Synecor, Llc | Intraluminal prostheses having polymeric material with selectively modified crystallinity and methods of making same |
WO2007047646A2 (en) * | 2005-10-14 | 2007-04-26 | Janssen Pharmaceutica, N.V. | Substituted dihydro-isoindolones useful in treating kinase disorders |
US20080021013A1 (en) * | 2006-07-21 | 2008-01-24 | Cephalon, Inc. | JAK inhibitors for treatment of myeloproliferative disorders |
CN103242404A (zh) * | 2012-02-03 | 2013-08-14 | 复旦大学 | N-鼠李糖基苯并咔唑化合物及其合成方法和在制药中的用途 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62220196A (ja) * | 1986-03-20 | 1987-09-28 | Kyowa Hakko Kogyo Co Ltd | 新規物質ucn―01 |
US4816450A (en) * | 1986-09-15 | 1989-03-28 | Duke University | Inhibition of protein kinase C by long-chain bases |
US4735939A (en) * | 1987-02-27 | 1988-04-05 | The Dow Chemical Company | Insecticidal activity of staurosporine |
US4923986A (en) * | 1987-03-09 | 1990-05-08 | Kyowa Hakko Kogyo Co., Ltd. | Derivatives of physiologically active substance K-252 |
JPH07113027B2 (ja) * | 1987-12-24 | 1995-12-06 | 協和醗酵工業株式会社 | K−252誘導体 |
US5438050A (en) * | 1988-02-06 | 1995-08-01 | Godecke Aktiengesellschaft | Indolocarbazole derivatives, processes for their preparation and compositions containing them |
DE3835842A1 (de) * | 1988-10-21 | 1990-04-26 | Goedecke Ag | Indolocarbazol-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel |
JP3010675B2 (ja) * | 1989-03-23 | 2000-02-21 | 萬有製薬株式会社 | 抗腫瘍性物質be―13793c |
US5618809A (en) * | 1989-12-14 | 1997-04-08 | Schering Corporation | Indolocarbazoles from saccharothrix aerocolonigenes copiosa subsp. nov SCC 1951 ATCC 53856 |
US5489608A (en) * | 1989-12-21 | 1996-02-06 | Goedecke Aktiengesellschaft | Indolocarbazole derivatives and the use thereof |
US5591842A (en) * | 1991-11-29 | 1997-01-07 | Banyu Pharmaceutical Co., Ltd. | Indolopyrrolocarbazole derivatives |
US6271242B1 (en) * | 1992-02-10 | 2001-08-07 | Bristol-Myers Squibb Co. | Method for treating cancer using a tyrosine protein kinase inhibitor |
JPH07504674A (ja) * | 1992-03-20 | 1995-05-25 | ザ・ウエルカム・ファウンデーション・リミテッド | 抗ウイルス活性を有する更なるインドール誘導体 |
DE4217963A1 (de) * | 1992-05-30 | 1993-12-02 | Goedecke Ag | Verwendung von Indolocarbazolen zur Behandlung von AIDS |
US5461146A (en) * | 1992-07-24 | 1995-10-24 | Cephalon, Inc. | Selected protein kinase inhibitors for the treatment of neurological disorders |
CA2163904C (en) * | 1993-05-28 | 2000-01-25 | Craig A. Dionne | Use of indolocarbazole derivatives to treat a pathological condition of the prostate |
US5468872A (en) * | 1993-09-16 | 1995-11-21 | Cephalon, Inc. | K-252a functional derivatives potentiate neurotrophin-3 for the treatment of neurological disorders |
US5591855A (en) * | 1994-10-14 | 1997-01-07 | Cephalon, Inc. | Fused pyrrolocarbazoles |
US5475110A (en) * | 1994-10-14 | 1995-12-12 | Cephalon, Inc. | Fused Pyrrolocarbazoles |
US5594009A (en) * | 1994-10-14 | 1997-01-14 | Cephalon, Inc. | Fused pyrrolocarbazoles |
US5705511A (en) * | 1994-10-14 | 1998-01-06 | Cephalon, Inc. | Fused pyrrolocarbazoles |
-
1996
- 1996-12-09 US US08/761,951 patent/US5808060A/en not_active Expired - Fee Related
- 1996-12-11 AT AT96943735T patent/ATE234284T1/de not_active IP Right Cessation
- 1996-12-11 EP EP96943735A patent/EP0871612B1/en not_active Expired - Lifetime
- 1996-12-11 BR BR9611947A patent/BR9611947A/pt not_active IP Right Cessation
- 1996-12-11 KR KR1019980704400A patent/KR100534528B1/ko not_active IP Right Cessation
- 1996-12-11 ES ES96943735T patent/ES2195033T3/es not_active Expired - Lifetime
- 1996-12-11 WO PCT/US1996/019853 patent/WO1997021677A1/en active IP Right Grant
- 1996-12-11 AU AU12893/97A patent/AU701412B2/en not_active Ceased
- 1996-12-11 PT PT96943735T patent/PT871612E/pt unknown
- 1996-12-11 DK DK96943735T patent/DK0871612T3/da active
- 1996-12-11 NZ NZ325073A patent/NZ325073A/en not_active IP Right Cessation
- 1996-12-11 CN CNB961998067A patent/CN1139573C/zh not_active Expired - Fee Related
- 1996-12-11 DE DE69626680T patent/DE69626680T2/de not_active Expired - Fee Related
- 1996-12-11 CA CA002239282A patent/CA2239282C/en not_active Expired - Fee Related
-
1999
- 1999-04-20 HK HK99101699A patent/HK1016599A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ES2195033T3 (es) | 2003-12-01 |
DE69626680T2 (de) | 2003-11-06 |
EP0871612B1 (en) | 2003-03-12 |
EP0871612A1 (en) | 1998-10-21 |
AU1289397A (en) | 1997-07-03 |
US5808060A (en) | 1998-09-15 |
BR9611947A (pt) | 1999-04-06 |
CN1139573C (zh) | 2004-02-25 |
CA2239282C (en) | 2009-08-18 |
NZ325073A (en) | 1999-04-29 |
HK1016599A1 (en) | 1999-11-05 |
KR19990072091A (ko) | 1999-09-27 |
KR100534528B1 (ko) | 2006-05-29 |
MX9804706A (es) | 1998-10-31 |
CN1224417A (zh) | 1999-07-28 |
WO1997021677A1 (en) | 1997-06-19 |
CA2239282A1 (en) | 1997-06-19 |
DK0871612T3 (da) | 2003-07-14 |
ATE234284T1 (de) | 2003-03-15 |
DE69626680D1 (de) | 2003-04-17 |
AU701412B2 (en) | 1999-01-28 |
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