PT86590A - 3-methylenespiro]benzofuranpiperidines" intermediates and a process for the preparation thereof and their use as medicaments - Google Patents
3-methylenespiro]benzofuranpiperidines" intermediates and a process for the preparation thereof and their use as medicamentsInfo
- Publication number
- PT86590A PT86590A PT86590A PT8659088A PT86590A PT 86590 A PT86590 A PT 86590A PT 86590 A PT86590 A PT 86590A PT 8659088 A PT8659088 A PT 8659088A PT 86590 A PT86590 A PT 86590A
- Authority
- PT
- Portugal
- Prior art keywords
- benzofuranpiperidines
- methylenespiro
- medicines
- intermediates
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/48—Oxygen atoms attached in position 4 having an acyclic carbon atom attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/006,035 US4788201A (en) | 1987-01-22 | 1987-01-22 | 3-methylenespiro (benzofuranpiperidines) |
Publications (2)
Publication Number | Publication Date |
---|---|
PT86590A true PT86590A (pt) | 1988-02-01 |
PT86590B PT86590B (pt) | 1991-12-31 |
Family
ID=21718967
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT86590A PT86590B (pt) | 1987-01-22 | 1988-01-21 | Processo para a preparacao de 3-metilenospiro {benzofuranpiperidinas} e seus intermediarios e de composicoes farmaceuticas que os contem |
Country Status (10)
Country | Link |
---|---|
US (1) | US4788201A (pt) |
EP (1) | EP0275962A3 (pt) |
JP (1) | JPS63192776A (pt) |
KR (1) | KR880009025A (pt) |
AU (1) | AU1065488A (pt) |
DK (1) | DK26588A (pt) |
HU (3) | HUT50825A (pt) |
IL (1) | IL85162A0 (pt) |
PT (1) | PT86590B (pt) |
ZA (1) | ZA88409B (pt) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2640266B2 (fr) * | 1988-07-12 | 1992-07-10 | Synthelabo | Derives de (hydroxy-1 piperidinyl-2 alkyl) indolones-2, quinoleinones-2, benzo(b)azepinones-2 et benzimidazolones-2, leur preparation et leur application en therapeutique |
JP2009507800A (ja) | 2005-09-09 | 2009-02-26 | ユーロ−セルティーク エス.エイ. | 縮合およびスピロ環化合物ならびにその使用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4420485A (en) * | 1982-09-29 | 1983-12-13 | Hoechst-Roussel Pharmaceuticals Inc. | 1'-[3-(1,2-Benzisoxazol-3-yl) proply]spiro[benzofuran-2(3H),3' or 4'-piperidines or 3'-pyrrolidines] |
US4452802A (en) * | 1983-08-25 | 1984-06-05 | Hoechst-Roussel Pharmaceuticals Incorporated | Antihypertensive spiro[benzofuran-azalkanes] |
-
1987
- 1987-01-22 US US07/006,035 patent/US4788201A/en not_active Expired - Lifetime
-
1988
- 1988-01-19 EP EP88100641A patent/EP0275962A3/en not_active Withdrawn
- 1988-01-21 KR KR1019880000431A patent/KR880009025A/ko not_active Application Discontinuation
- 1988-01-21 ZA ZA88409A patent/ZA88409B/xx unknown
- 1988-01-21 AU AU10654/88A patent/AU1065488A/en not_active Abandoned
- 1988-01-21 IL IL85162A patent/IL85162A0/xx unknown
- 1988-01-21 DK DK026588A patent/DK26588A/da not_active Application Discontinuation
- 1988-01-21 JP JP63009768A patent/JPS63192776A/ja active Pending
- 1988-01-21 PT PT86590A patent/PT86590B/pt not_active IP Right Cessation
- 1988-01-22 HU HU88256A patent/HUT50825A/hu unknown
- 1988-01-22 HU HU895666A patent/HUT52052A/hu unknown
- 1988-01-22 HU HU895666A patent/HU895666D0/hu unknown
Also Published As
Publication number | Publication date |
---|---|
DK26588A (da) | 1988-07-23 |
KR880009025A (ko) | 1988-09-13 |
PT86590B (pt) | 1991-12-31 |
JPS63192776A (ja) | 1988-08-10 |
US4788201A (en) | 1988-11-29 |
HU895666D0 (en) | 1990-03-28 |
IL85162A0 (en) | 1988-06-30 |
HUT52052A (en) | 1990-06-28 |
ZA88409B (en) | 1988-09-28 |
EP0275962A2 (en) | 1988-07-27 |
EP0275962A3 (en) | 1989-09-13 |
DK26588D0 (da) | 1988-01-21 |
AU1065488A (en) | 1988-07-28 |
HUT50825A (en) | 1990-03-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19921231 |