PT85538A - Process for preparing homogeneous recombinant immune interferon fragments - Google Patents

Process for preparing homogeneous recombinant immune interferon fragments

Info

Publication number
PT85538A
PT85538A PT85538A PT8553887A PT85538A PT 85538 A PT85538 A PT 85538A PT 85538 A PT85538 A PT 85538A PT 8553887 A PT8553887 A PT 8553887A PT 85538 A PT85538 A PT 85538A
Authority
PT
Portugal
Prior art keywords
immune interferon
homogeneous recombinant
recombinant immune
preparing homogeneous
interferon fragments
Prior art date
Application number
PT85538A
Other languages
English (en)
Other versions
PT85538B (pt
Inventor
Heinz Doebeli
Erich Hochuli
Reiner Gentz
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PT85538A publication Critical patent/PT85538A/pt
Publication of PT85538B publication Critical patent/PT85538B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/57—IFN-gamma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Plant Pathology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PT85538A 1986-08-13 1987-08-13 Processo para a preparacao de fragmentos de interferon imunogenicos recombinantes homogeneos PT85538B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868619725A GB8619725D0 (en) 1986-08-13 1986-08-13 Homogenous interferon fragments

Publications (2)

Publication Number Publication Date
PT85538A true PT85538A (en) 1987-09-01
PT85538B PT85538B (pt) 1990-06-29

Family

ID=10602667

Family Applications (1)

Application Number Title Priority Date Filing Date
PT85538A PT85538B (pt) 1986-08-13 1987-08-13 Processo para a preparacao de fragmentos de interferon imunogenicos recombinantes homogeneos

Country Status (21)

Country Link
EP (1) EP0256424B1 (pt)
JP (1) JPS6349098A (pt)
KR (1) KR880002996A (pt)
AR (1) AR244808A1 (pt)
AT (1) ATE67783T1 (pt)
AU (1) AU607930B2 (pt)
DE (1) DE3773295D1 (pt)
DK (1) DK377787A (pt)
ES (1) ES2051714T3 (pt)
FI (1) FI873512L (pt)
GB (1) GB8619725D0 (pt)
GR (1) GR3003417T3 (pt)
HU (1) HU202920B (pt)
IE (1) IE60670B1 (pt)
IL (1) IL83474A0 (pt)
MC (1) MC1847A1 (pt)
NO (1) NO174631C (pt)
NZ (1) NZ221374A (pt)
PH (1) PH27432A (pt)
PT (1) PT85538B (pt)
ZA (1) ZA875819B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2969461B2 (ja) * 1988-07-23 1999-11-02 株式会社林原生物化学研究所 ヒトγ−インターフェロンとその製造方法並びに用途
DE3730331A1 (de) * 1987-09-10 1989-03-30 Basf Ag Neue polypeptide, verfahren zur herstellung, die vektoren dafuer und arzneimittel daraus
ATE112686T1 (de) * 1990-08-31 1994-10-15 Schering Corp Verwendungsmethoden von humanem gammainterferon 4-134.
DE4036856C1 (pt) * 1990-11-19 1992-05-27 Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung Ev, 8000 Muenchen, De
US6258550B1 (en) 1993-04-23 2001-07-10 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
YU32402A (sh) 1999-11-12 2005-03-15 Maxygen Holdings Ltd. Konjugati gama interferona
BR0015506A (pt) 1999-11-12 2002-07-23 Maxygen Holdings Ltd Conjugados de interferon gama, métodos para sua preparação, composições farmacêuticas que compreendem ás moléculas e seu uso no tratamento de doenças
US7959910B2 (en) 2000-07-31 2011-06-14 Biolex Therapeutics, Inc. C-terminally truncated interferon alpha variants
US7038015B2 (en) 2001-04-06 2006-05-02 Maxygen Holdings, Ltd. Interferon gamma polypeptide variants
US6958388B2 (en) 2001-04-06 2005-10-25 Maxygen, Aps Interferon gamma polypeptide variants
US7524931B2 (en) 2002-07-03 2009-04-28 Maxygen Holdings Ltd. Full-length interferon gamma polypeptide variants
US20060024272A1 (en) * 2004-07-29 2006-02-02 Large Scale Biology Corporation C-terminally truncated interferon

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0788398B2 (ja) * 1983-10-17 1995-09-27 サントリー株式会社 新規生理活性ポリペプチドおよびその製造法
US4855238A (en) * 1983-12-16 1989-08-08 Genentech, Inc. Recombinant gamma interferons having enhanced stability and methods therefor
JPS60172999A (ja) * 1983-12-20 1985-09-06 Suntory Ltd 新規な塩基性ポリペプチドおよびその製造法
US4758656A (en) * 1983-12-26 1988-07-19 Kyowa Hakko Kogyo Co., Ltd. Novel human interferon-gamma polypeptide derivative
DE3414831A1 (de) * 1984-04-19 1985-10-31 Hoechst Ag, 6230 Frankfurt Herstellung von polypeptiden mit human-gammainterferon-aktivitaet
IL75302A0 (en) * 1984-06-06 1985-09-29 Takeda Chemical Industries Ltd Novel polypeptide and production thereof
WO1985005618A1 (fr) * 1984-06-06 1985-12-19 Takeda Chemical Industries, Ltd. Procede de preparation de derives de l'interferon
JPS6124599A (ja) * 1984-07-11 1986-02-03 Kyowa Hakko Kogyo Co Ltd 新規ヒトインタ−フエロン−ｒポリペプチド誘導体
JPS6163696A (ja) * 1984-09-05 1986-04-01 Asahi Chem Ind Co Ltd 新しいペプチド
JPS61108397A (ja) * 1984-10-31 1986-05-27 Green Cross Corp:The インタ−フエロン−γ蛋白質の製造法
JPS62289600A (ja) * 1986-02-18 1987-12-16 Kanegafuchi Chem Ind Co Ltd インタ−フエロン−γ及びその製造方法

Also Published As

Publication number Publication date
ATE67783T1 (de) 1991-10-15
IL83474A0 (en) 1988-01-31
EP0256424A1 (en) 1988-02-24
PH27432A (en) 1993-06-21
MC1847A1 (fr) 1988-09-30
NO873389D0 (no) 1987-08-12
FI873512A7 (fi) 1988-02-14
ES2051714T3 (es) 1994-07-01
AR244808A1 (es) 1993-11-30
GB8619725D0 (en) 1986-09-24
FI873512A0 (fi) 1987-08-13
AU7668687A (en) 1988-05-19
NO174631C (no) 1994-06-08
EP0256424B1 (en) 1991-09-25
NZ221374A (en) 1990-07-26
DK377787A (da) 1988-02-14
NO174631B (no) 1994-02-28
KR880002996A (ko) 1988-05-13
DK377787D0 (da) 1987-07-20
JPS6349098A (ja) 1988-03-01
HUT47148A (en) 1989-01-30
GR3003417T3 (en) 1993-02-17
AU607930B2 (en) 1991-03-21
DE3773295D1 (de) 1991-10-31
HU202920B (en) 1991-04-29
NO873389L (no) 1988-02-15
IE872160L (en) 1988-02-13
IE60670B1 (en) 1994-08-10
ZA875819B (en) 1988-02-15
FI873512L (fi) 1988-02-14
PT85538B (pt) 1990-06-29

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Legal Events

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MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19950630