PT84539B - Processo para a preparacao de anilidas substituidas de acido oleico, linoleico, ou linolenico como inibidores de acilcoa: acil-transferase do colesterol - Google Patents
Processo para a preparacao de anilidas substituidas de acido oleico, linoleico, ou linolenico como inibidores de acilcoa: acil-transferase do colesterolInfo
- Publication number
- PT84539B PT84539B PT84539A PT8453987A PT84539B PT 84539 B PT84539 B PT 84539B PT 84539 A PT84539 A PT 84539A PT 8453987 A PT8453987 A PT 8453987A PT 84539 B PT84539 B PT 84539B
- Authority
- PT
- Portugal
- Prior art keywords
- acilcoa
- linoleic
- transferase
- inhibitors
- preparation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C233/09—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an acyclic unsaturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84342086A | 1986-03-24 | 1986-03-24 | |
| US07/001,561 US4751026A (en) | 1986-03-24 | 1987-01-16 | Substituted anilides of oleic, linoleic, or linolenic acid as inhibitors of acyl-coa:cholesterol acyltransferase |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT84539A PT84539A (en) | 1987-04-01 |
| PT84539B true PT84539B (pt) | 1989-11-10 |
Family
ID=26669197
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT84539A PT84539B (pt) | 1986-03-24 | 1987-03-23 | Processo para a preparacao de anilidas substituidas de acido oleico, linoleico, ou linolenico como inibidores de acilcoa: acil-transferase do colesterol |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4751026A (pt) |
| EP (1) | EP0242610A1 (pt) |
| KR (1) | KR900006760B1 (pt) |
| AU (1) | AU597339B2 (pt) |
| CA (1) | CA1263964A (pt) |
| DK (1) | DK141787A (pt) |
| FI (1) | FI871257A (pt) |
| NO (1) | NO871190L (pt) |
| NZ (1) | NZ219734A (pt) |
| PH (1) | PH23490A (pt) |
| PT (1) | PT84539B (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4859703A (en) * | 1987-06-15 | 1989-08-22 | Warner-Lambert Company | Lipid regulating compositions |
| US5290814A (en) * | 1988-11-21 | 1994-03-01 | Burroughs Wellcome Co. | Anti-atherosclerotic diaryl compounds |
| FR2673625B1 (fr) * | 1991-03-08 | 1993-05-07 | Adir | Nouveaux derives d'acylaminophenol, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| JPH07503737A (ja) * | 1992-05-28 | 1995-04-20 | フアイザー・インコーポレイテツド | アシル補酵素ａ：コレステロールアシルトランスフェラーゼ（ａｃａｔ）の阻害剤としての新規なｎ−アリールおよびｎ−ヘテロアリール尿素誘導体 |
| US6133326A (en) | 1994-08-31 | 2000-10-17 | Pfizer Inc | Compositions and methods for decreasing sebum production |
| DE69600396T2 (de) * | 1995-02-08 | 1998-10-29 | Nippon Shoji Kaisha Ltd | Anilinderivate, die einen mehrfach ungesättigten Fettsäurerest tragen und ihre Anwendung |
| KR20020073574A (ko) | 2000-02-02 | 2002-09-27 | 워너-램버트 캄파니 | 피지선 장애 치료용 콜레스테롤 에스테르 및 왁스에스테르 합성 이중 억제제 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE306730B (pt) * | 1963-02-06 | 1968-12-09 | Sumitomo Chemical Co | |
| NL130295C (pt) * | 1964-04-28 | |||
| SE353319B (pt) * | 1964-08-15 | 1973-01-29 | Sumitomo Chemical Co | |
| NL132935C (pt) * | 1964-12-04 | |||
| AU415780B2 (pt) * | 1966-02-10 | 1971-08-10 | ||
| ZA7987B (en) * | 1978-01-09 | 1980-08-27 | Sandoz Ltd | Long-chain fatty acid amides and hydrazides and cyclopropano analogues thereof,their production and their use as anti-atherosclerotic agents |
-
1987
- 1987-01-16 US US07/001,561 patent/US4751026A/en not_active Expired - Fee Related
- 1987-03-04 AU AU69671/87A patent/AU597339B2/en not_active Ceased
- 1987-03-05 CA CA000531250A patent/CA1263964A/en not_active Expired
- 1987-03-19 DK DK141787A patent/DK141787A/da not_active IP Right Cessation
- 1987-03-20 FI FI871257A patent/FI871257A/fi not_active Application Discontinuation
- 1987-03-21 KR KR1019870002579A patent/KR900006760B1/ko not_active IP Right Cessation
- 1987-03-23 PH PH35063A patent/PH23490A/en unknown
- 1987-03-23 NO NO871190A patent/NO871190L/no unknown
- 1987-03-23 EP EP87104237A patent/EP0242610A1/en not_active Withdrawn
- 1987-03-23 PT PT84539A patent/PT84539B/pt not_active IP Right Cessation
- 1987-03-23 NZ NZ219734A patent/NZ219734A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PH23490A (en) | 1989-08-16 |
| CA1263964A (en) | 1989-12-19 |
| FI871257A0 (fi) | 1987-03-20 |
| NO871190D0 (no) | 1987-03-23 |
| AU597339B2 (en) | 1990-05-31 |
| PT84539A (en) | 1987-04-01 |
| DK141787D0 (da) | 1987-03-19 |
| FI871257A (fi) | 1987-09-25 |
| KR900006760B1 (ko) | 1990-09-21 |
| NZ219734A (en) | 1989-11-28 |
| AU6967187A (en) | 1987-10-01 |
| EP0242610A1 (en) | 1987-10-28 |
| KR870008834A (ko) | 1987-10-21 |
| NO871190L (no) | 1987-09-25 |
| US4751026A (en) | 1988-06-14 |
| DK141787A (da) | 1987-09-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19921031 |