FI871257A0 - Substituerade anilider av olje-, linol- och linolensyra saosom inhibitorer av acyl-coa:kolesterol-acyltransferas. - Google Patents

Substituerade anilider av olje-, linol- och linolensyra saosom inhibitorer av acyl-coa:kolesterol-acyltransferas.

Info

Publication number
FI871257A0
FI871257A0 FI871257A FI871257A FI871257A0 FI 871257 A0 FI871257 A0 FI 871257A0 FI 871257 A FI871257 A FI 871257A FI 871257 A FI871257 A FI 871257A FI 871257 A0 FI871257 A0 FI 871257A0
Authority
FI
Finland
Prior art keywords
olje
linolensyra
anilider
acyltransferas
inhibitorer
Prior art date
Application number
FI871257A
Other languages
English (en)
Other versions
FI871257A (fi
Inventor
Milton Louis Hoefle
Ann Holmes
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of FI871257A0 publication Critical patent/FI871257A0/fi
Publication of FI871257A publication Critical patent/FI871257A/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/09—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an acyclic unsaturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI871257A 1986-03-24 1987-03-20 Substituerade anilider av olje-, linol- och linolensyra saosom inhibitorer av acyl-coa:kolesterol-acyltransferas. FI871257A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84342086A 1986-03-24 1986-03-24
US07/001,561 US4751026A (en) 1986-03-24 1987-01-16 Substituted anilides of oleic, linoleic, or linolenic acid as inhibitors of acyl-coa:cholesterol acyltransferase

Publications (2)

Publication Number Publication Date
FI871257A0 true FI871257A0 (fi) 1987-03-20
FI871257A FI871257A (fi) 1987-09-25

Family

ID=26669197

Family Applications (1)

Application Number Title Priority Date Filing Date
FI871257A FI871257A (fi) 1986-03-24 1987-03-20 Substituerade anilider av olje-, linol- och linolensyra saosom inhibitorer av acyl-coa:kolesterol-acyltransferas.

Country Status (11)

Country Link
US (1) US4751026A (fi)
EP (1) EP0242610A1 (fi)
KR (1) KR900006760B1 (fi)
AU (1) AU597339B2 (fi)
CA (1) CA1263964A (fi)
DK (1) DK141787A (fi)
FI (1) FI871257A (fi)
NO (1) NO871190L (fi)
NZ (1) NZ219734A (fi)
PH (1) PH23490A (fi)
PT (1) PT84539B (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4859703A (en) * 1987-06-15 1989-08-22 Warner-Lambert Company Lipid regulating compositions
US5290814A (en) * 1988-11-21 1994-03-01 Burroughs Wellcome Co. Anti-atherosclerotic diaryl compounds
FR2673625B1 (fr) * 1991-03-08 1993-05-07 Adir Nouveaux derives d'acylaminophenol, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
KR950701621A (ko) * 1992-05-28 1995-04-28 알렌 제이. 스피겔 아실 조효소a : 콜레스테롤 아실 전이효소(acat)의 억제제로서 신규한 n- 아릴 및 n- 헤테로아릴우레아 유도체(new n-aryl and n-heteroarylurea derivatives as inhibitors of acyl coenzyme a : cholesterol acyl transferase(acat)
US6133326A (en) 1994-08-31 2000-10-17 Pfizer Inc Compositions and methods for decreasing sebum production
DE69600396T2 (de) * 1995-02-08 1998-10-29 Nippon Shoji Kaisha Ltd Anilinderivate, die einen mehrfach ungesättigten Fettsäurerest tragen und ihre Anwendung
CA2398219A1 (en) 2000-02-02 2001-08-09 Warner-Lambert Company Dual inhibitors of cholesterol ester and wax ester synthesis for sebaceous gland disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE306730B (fi) * 1963-02-06 1968-12-09 Sumitomo Chemical Co
NL130295C (fi) * 1964-04-28
SE353319B (fi) * 1964-08-15 1973-01-29 Sumitomo Chemical Co
NL132935C (fi) * 1964-12-04
AU415780B2 (fi) * 1966-02-10 1971-08-10
PH15414A (en) * 1978-01-09 1983-01-07 Sandoz Ag Unsaturated fatty acid amides of tryptophan derivatives

Also Published As

Publication number Publication date
NO871190L (no) 1987-09-25
AU597339B2 (en) 1990-05-31
NO871190D0 (no) 1987-03-23
EP0242610A1 (en) 1987-10-28
AU6967187A (en) 1987-10-01
CA1263964A (en) 1989-12-19
KR870008834A (ko) 1987-10-21
PT84539A (en) 1987-04-01
DK141787A (da) 1987-09-25
FI871257A (fi) 1987-09-25
NZ219734A (en) 1989-11-28
KR900006760B1 (ko) 1990-09-21
US4751026A (en) 1988-06-14
DK141787D0 (da) 1987-03-19
PT84539B (pt) 1989-11-10
PH23490A (en) 1989-08-16

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: WARNER-LAMBERT COMPANY