PT78947B - Process for preparing 1,4-dihydropyridines useful as medicaments - Google Patents

Process for preparing 1,4-dihydropyridines useful as medicaments

Info

Publication number
PT78947B
PT78947B PT78947A PT7894784A PT78947B PT 78947 B PT78947 B PT 78947B PT 78947 A PT78947 A PT 78947A PT 7894784 A PT7894784 A PT 7894784A PT 78947 B PT78947 B PT 78947B
Authority
PT
Portugal
Prior art keywords
image
alkyl
halogenoalkoxy
halogenoalkyl
sulphur
Prior art date
Application number
PT78947A
Other languages
English (en)
Other versions
PT78947A (en
Inventor
Fred Robert Heiker
Juergen Stoltefuss
Gerhard Franckowiak
Matthias Schramm
Guenter Thomas
Rainer Gross
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of PT78947A publication Critical patent/PT78947A/pt
Publication of PT78947B publication Critical patent/PT78947B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/06—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical being a hydroxyalkyl group esterified by a fatty acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Saccharide Compounds (AREA)
PT78947A 1983-07-22 1984-07-19 Process for preparing 1,4-dihydropyridines useful as medicaments PT78947B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833326384 DE3326384A1 (de) 1983-07-22 1983-07-22 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln

Publications (2)

Publication Number Publication Date
PT78947A PT78947A (en) 1984-08-01
PT78947B true PT78947B (en) 1986-06-02

Family

ID=6204598

Family Applications (1)

Application Number Title Priority Date Filing Date
PT78947A PT78947B (en) 1983-07-22 1984-07-19 Process for preparing 1,4-dihydropyridines useful as medicaments

Country Status (14)

Country Link
US (1) US4537881A (pt)
EP (1) EP0139859B1 (pt)
JP (1) JPS6042393A (pt)
KR (1) KR850001204A (pt)
AT (1) ATE38041T1 (pt)
AU (1) AU564069B2 (pt)
CA (1) CA1229590A (pt)
DE (2) DE3326384A1 (pt)
ES (3) ES534508A0 (pt)
GR (1) GR82104B (pt)
HU (1) HUT36092A (pt)
IL (1) IL72454A (pt)
PT (1) PT78947B (pt)
ZA (1) ZA845626B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT39179A (en) * 1984-12-10 1986-08-28 Sandoz Ag Process for production of derivatives of 1,4-dihydro-piridin
US4868181A (en) * 1986-08-04 1989-09-19 E. I. Du Pont De Nemours And Company 1,4-dihydropyridine derivatives with calcium agonist and alpha1 -antagonist activity
JPH02167262A (ja) * 1988-06-05 1990-06-27 Taisho Pharmaceut Co Ltd １，４―ジヒドロピリジン誘導体
US5166148A (en) * 1990-07-09 1992-11-24 The Du Pont Merck Pharmaceutical Company 2-amino-1,4-dihydropyridine derivatives with calcium agonist and alpha1 -antagonist activity
GB9119983D0 (en) * 1991-09-19 1991-11-06 Erba Carlo Spa Dihydropyridine derivatives useful in antitumor therapy

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2641746C2 (de) * 1976-09-16 1986-11-06 Bayer Ag, 5090 Leverkusen 1,4-Dihydropyridin-Zuckerderivate, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
DE2752820A1 (de) * 1977-11-26 1979-05-31 Bayer Ag Neue nitrosubstituierte 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
PT78947A (en) 1984-08-01
HUT36092A (en) 1985-08-28
JPS6042393A (ja) 1985-03-06
ES8604149A1 (es) 1986-01-16
ZA845626B (en) 1985-03-27
IL72454A (en) 1987-11-30
EP0139859A2 (de) 1985-05-08
AU3088784A (en) 1985-01-24
CA1229590A (en) 1987-11-24
DE3474669D1 (en) 1988-11-24
EP0139859B1 (de) 1988-10-19
ES8602662A1 (es) 1985-12-01
US4537881A (en) 1985-08-27
DE3326384A1 (de) 1985-01-31
ES534508A0 (es) 1985-12-01
IL72454A0 (en) 1984-11-30
KR850001204A (ko) 1985-03-16
ATE38041T1 (de) 1988-11-15
ES8604150A1 (es) 1986-01-16
GR82104B (pt) 1984-12-13
EP0139859A3 (en) 1986-08-20
ES543741A0 (es) 1986-01-16
AU564069B2 (en) 1987-07-30
ES543742A0 (es) 1986-01-16

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