PT78778B - Process for preparing novel thiazolidine derivatives and of pharmaceutical compositions containing the same - Google Patents

Process for preparing novel thiazolidine derivatives and of pharmaceutical compositions containing the same

Info

Publication number
PT78778B
PT78778B PT78778A PT7877884A PT78778B PT 78778 B PT78778 B PT 78778B PT 78778 A PT78778 A PT 78778A PT 7877884 A PT7877884 A PT 7877884A PT 78778 B PT78778 B PT 78778B
Authority
PT
Portugal
Prior art keywords
same
pharmaceutical compositions
compositions containing
preparing novel
thiazolidine derivatives
Prior art date
Application number
PT78778A
Other languages
English (en)
Other versions
PT78778A (en
Inventor
Heinz Hasler
Fernand Schneider
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PT78778A publication Critical patent/PT78778A/pt
Publication of PT78778B publication Critical patent/PT78778B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/08Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT78778A 1983-06-23 1984-06-20 Process for preparing novel thiazolidine derivatives and of pharmaceutical compositions containing the same PT78778B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH343283 1983-06-23
CH186084 1984-04-13

Publications (2)

Publication Number Publication Date
PT78778A PT78778A (en) 1984-07-01
PT78778B true PT78778B (en) 1986-09-15

Family

ID=25688868

Family Applications (1)

Application Number Title Priority Date Filing Date
PT78778A PT78778B (en) 1983-06-23 1984-06-20 Process for preparing novel thiazolidine derivatives and of pharmaceutical compositions containing the same

Country Status (11)

Country Link
US (1) US4587256A (pt)
EP (1) EP0129747A3 (pt)
AU (1) AU2947784A (pt)
DK (1) DK277484A (pt)
ES (4) ES533624A0 (pt)
FI (1) FI842327A (pt)
HU (1) HUT34509A (pt)
IL (1) IL72139A0 (pt)
MC (1) MC1601A1 (pt)
NO (1) NO842515L (pt)
PT (1) PT78778B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4537892A (en) * 1983-09-14 1985-08-27 Alcon Laboratories, Inc. Spiro-tricyclicaromatic succinimide derivatives as inhibitors of aldose reductase
JPH06772B2 (ja) * 1984-07-09 1994-01-05 鐘淵化学工業株式会社 3―(4―フルオロフエノキシ)プロピオニトリルを用いる6―フルオロ―4―クロマノンの製造法
JPS61200991A (ja) * 1985-03-04 1986-09-05 Sanwa Kagaku Kenkyusho:Kk スピロ―3―ヘテロアゾリジン化合物、その製法及びそれを有効成分とする糖尿病合併症の予防及び治療剤
AU617541B2 (en) * 1988-10-20 1991-11-28 Wyeth Spiro-isoquinoline-pyrrolidine tetrones and analogs thereof useful as aldose reductase inhibitors
US6756360B1 (en) 1998-12-24 2004-06-29 Metabasis Therapeutics, Inc. Combination of FBPase inhibitors and insulin sensitizers for the treatment of diabetes
CN1740182A (zh) * 1999-12-22 2006-03-01 症变治疗公司 新的双氨基化膦酸酯前药
US7563774B2 (en) 2000-06-29 2009-07-21 Metabasis Therapeutics, Inc. Combination of FBPase inhibitors and antidiabetic agents useful for the treatment of diabetes
US6812355B2 (en) 2002-10-22 2004-11-02 Sekhsaria Chemicals Limited Process for the manufacture of citalopram hydrobromide from 5-bromophthalide
EA014419B1 (ru) * 2004-05-24 2010-12-30 Эмджен Инк. 5,5-дизамещённые-2-амино-4-тиазолидиноны и способ их получения, фармацевтическая композиция и способ лечения
US8686011B2 (en) 2004-05-24 2014-04-01 Amgen Inc. Inhibitors of 11-β-hydroxy steroid dehydrogenase type 1
EP1778250A2 (en) * 2004-08-18 2007-05-02 Metabasis Therapeutics, Inc. Novel thiazole inhibitors of fructose 1,6-bisphosphatase
US7828840B2 (en) * 2007-11-15 2010-11-09 Med Institute, Inc. Medical devices and methods for local delivery of angiotensin II type 2 receptor antagonists
CN115322208B (zh) * 2021-05-10 2023-04-11 中国药科大学 2-氨基噻唑类衍生物及其制备方法和医药用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4210756A (en) * 1976-10-18 1980-07-01 Pfizer Inc. Tetrahydroquinoline hydantoins for chronic diabetic complications
US4200642A (en) * 1978-08-21 1980-04-29 Pfizer Inc. Spiro-oxazolidindiones
US4226875A (en) * 1979-04-02 1980-10-07 Pfizer Inc. Novel spiro-oxazolidinediones
US4248882A (en) * 1980-02-12 1981-02-03 Pfizer Inc. Treating diabetes-associated complications with hydantoin amines

Also Published As

Publication number Publication date
ES8602820A1 (es) 1985-12-16
PT78778A (en) 1984-07-01
MC1601A1 (fr) 1985-05-09
NO842515L (no) 1984-12-27
ES541705A0 (es) 1985-12-01
DK277484A (da) 1984-12-24
ES541708A0 (es) 1985-12-01
HUT34509A (en) 1985-03-28
DK277484D0 (da) 1984-06-04
ES8602718A1 (es) 1985-12-01
ES8602719A1 (es) 1985-12-01
ES533624A0 (es) 1985-12-16
ES541707A0 (es) 1985-12-01
AU2947784A (en) 1985-01-03
FI842327A (fi) 1984-12-24
ES8602716A1 (es) 1985-12-01
IL72139A0 (en) 1984-10-31
FI842327A0 (fi) 1984-06-08
EP0129747A3 (de) 1985-09-25
US4587256A (en) 1986-05-06
EP0129747A2 (de) 1985-01-02

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