PT70716A - Process for the preparation of novel spiro-quinolylhydantoin derivatives - Google Patents
Process for the preparation of novel spiro-quinolylhydantoin derivativesInfo
- Publication number
- PT70716A PT70716A PT70716A PT7071680A PT70716A PT 70716 A PT70716 A PT 70716A PT 70716 A PT70716 A PT 70716A PT 7071680 A PT7071680 A PT 7071680A PT 70716 A PT70716 A PT 70716A
- Authority
- PT
- Portugal
- Prior art keywords
- quinolylhydantoin
- derivatives
- preparation
- novel spiro
- spiro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/20—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/20—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/005,278 US4176185A (en) | 1979-01-22 | 1979-01-22 | Spiro-quinolylhydantoins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT70716A true PT70716A (en) | 1980-02-01 |
Family
ID=21715098
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT70716A PT70716A (en) | 1979-01-22 | 1980-01-21 | Process for the preparation of novel spiro-quinolylhydantoin derivatives |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4176185A (pt) |
| EP (1) | EP0014079B1 (pt) |
| JP (1) | JPS5840959B2 (pt) |
| KR (1) | KR830001940A (pt) |
| AR (1) | AR222685A1 (pt) |
| AT (1) | AT365588B (pt) |
| AU (1) | AU514271B2 (pt) |
| CA (1) | CA1140928A (pt) |
| DE (1) | DE3060079D1 (pt) |
| DK (1) | DK156399C (pt) |
| EG (1) | EG15085A (pt) |
| ES (1) | ES487923A0 (pt) |
| FI (1) | FI69308C (pt) |
| GR (1) | GR72408B (pt) |
| IE (1) | IE49365B1 (pt) |
| IL (1) | IL59177A (pt) |
| NO (1) | NO152172C (pt) |
| NZ (1) | NZ192650A (pt) |
| PH (1) | PH15472A (pt) |
| PT (1) | PT70716A (pt) |
| YU (1) | YU41692B (pt) |
| ZA (1) | ZA80344B (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4176185A (en) * | 1979-01-22 | 1979-11-27 | Pfizer Inc. | Spiro-quinolylhydantoins |
| AU532110B2 (en) * | 1979-11-13 | 1983-09-15 | Ici Ltd. | Spiro(imidazolidine-4,3:-indoline)-2,2:5-trione derivatives |
| US4248882A (en) * | 1980-02-12 | 1981-02-03 | Pfizer Inc. | Treating diabetes-associated complications with hydantoin amines |
| JPS5745185A (en) * | 1980-07-21 | 1982-03-13 | Eisai Co Ltd | Hydantoin derivative and its preparation |
| DE3261684D1 (en) * | 1981-05-12 | 1985-02-07 | Ici Plc | Pyrrole derivatives |
| HU204832B (en) * | 1987-09-04 | 1992-02-28 | Pfizer | Process for producing spiro-(imidazolidine-4,4'-pyrano/2,3-b/pyridine) derivatives and pharmaceutical compositions comprising same |
| US5068333A (en) * | 1990-03-07 | 1991-11-26 | Pfizer Inc. | 6-chloro-3,4-dihydro-pyrano [2,3-b]pyridines having the R configuration |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1135915B (de) * | 1961-06-29 | 1962-09-06 | Asta Werke Ag Chem Fab | Verfahren zur Herstellung neuer, antikonvulsiv wirksamer Spirohydantoine |
| US3876659A (en) * | 1970-09-18 | 1975-04-08 | Sandoz Ag | Spiro tricyclic isoindolines |
| US4117230A (en) * | 1976-10-18 | 1978-09-26 | Pfizer Inc. | Hydantoin derivatives as therapeutic agents |
| US4176185A (en) * | 1979-01-22 | 1979-11-27 | Pfizer Inc. | Spiro-quinolylhydantoins |
-
1979
- 1979-01-22 US US06/005,278 patent/US4176185A/en not_active Expired - Lifetime
- 1979-12-28 NO NO794318A patent/NO152172C/no unknown
-
1980
- 1980-01-12 EG EG36/80A patent/EG15085A/xx active
- 1980-01-18 CA CA000343984A patent/CA1140928A/en not_active Expired
- 1980-01-18 AR AR279683A patent/AR222685A1/es active
- 1980-01-18 AT AT0026780A patent/AT365588B/de not_active IP Right Cessation
- 1980-01-18 EP EP80300170A patent/EP0014079B1/en not_active Expired
- 1980-01-18 DE DE8080300170T patent/DE3060079D1/de not_active Expired
- 1980-01-18 YU YU131/80A patent/YU41692B/xx unknown
- 1980-01-18 NZ NZ192650A patent/NZ192650A/en unknown
- 1980-01-21 IL IL59177A patent/IL59177A/xx unknown
- 1980-01-21 AU AU54766/80A patent/AU514271B2/en not_active Ceased
- 1980-01-21 FI FI800163A patent/FI69308C/fi not_active IP Right Cessation
- 1980-01-21 JP JP55005610A patent/JPS5840959B2/ja not_active Expired
- 1980-01-21 KR KR1019800000213A patent/KR830001940A/ko unknown
- 1980-01-21 ZA ZA00800344A patent/ZA80344B/xx unknown
- 1980-01-21 PH PH23529A patent/PH15472A/en unknown
- 1980-01-21 IE IE109/80A patent/IE49365B1/en unknown
- 1980-01-21 DK DK024280A patent/DK156399C/da not_active IP Right Cessation
- 1980-01-21 PT PT70716A patent/PT70716A/pt not_active IP Right Cessation
- 1980-01-22 ES ES487923A patent/ES487923A0/es active Granted
- 1980-11-21 GR GR60999A patent/GR72408B/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US4176185A (en) | 1979-11-27 |
| PH15472A (en) | 1983-01-24 |
| IE800109L (en) | 1980-07-22 |
| ES8103090A1 (es) | 1981-02-16 |
| EP0014079B1 (en) | 1981-11-18 |
| NO794318L (no) | 1980-07-23 |
| FI69308C (fi) | 1986-01-10 |
| DK156399B (da) | 1989-08-14 |
| EG15085A (en) | 1986-12-30 |
| CA1140928A (en) | 1983-02-08 |
| JPS5840959B2 (ja) | 1983-09-08 |
| AT365588B (de) | 1982-01-25 |
| NO152172C (no) | 1985-08-14 |
| FI69308B (fi) | 1985-09-30 |
| DK24280A (da) | 1980-07-23 |
| GR72408B (pt) | 1983-11-02 |
| DE3060079D1 (en) | 1982-01-21 |
| IL59177A (en) | 1982-11-30 |
| YU41692B (en) | 1987-12-31 |
| ES487923A0 (es) | 1981-02-16 |
| ZA80344B (en) | 1981-02-25 |
| AU514271B2 (en) | 1981-01-29 |
| AR222685A1 (es) | 1981-06-15 |
| EP0014079A1 (en) | 1980-08-06 |
| DK156399C (da) | 1990-01-08 |
| NO152172B (no) | 1985-05-06 |
| IL59177A0 (en) | 1980-05-30 |
| FI800163A (fi) | 1980-07-23 |
| KR830001940A (ko) | 1983-05-19 |
| NZ192650A (en) | 1984-04-27 |
| JPS55108873A (en) | 1980-08-21 |
| YU13180A (en) | 1983-01-21 |
| ATA26780A (de) | 1981-06-15 |
| AU5476680A (en) | 1980-07-31 |
| IE49365B1 (en) | 1985-09-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19920714 |