PT65845B - Process for the preparation of antibiotics - Google Patents

Process for the preparation of antibiotics

Info

Publication number
PT65845B
PT65845B PT65845A PT6584576A PT65845B PT 65845 B PT65845 B PT 65845B PT 65845 A PT65845 A PT 65845A PT 6584576 A PT6584576 A PT 6584576A PT 65845 B PT65845 B PT 65845B
Authority
PT
Portugal
Prior art keywords
antibiotics
preparation
Prior art date
Application number
PT65845A
Other languages
English (en)
Portuguese (pt)
Other versions
PT65845A (en
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of PT65845A publication Critical patent/PT65845A/pt
Publication of PT65845B publication Critical patent/PT65845B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/182Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
    • C12P17/184Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system containing a beta-lactam ring, e.g. thienamycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT65845A 1975-11-24 1976-11-16 Process for the preparation of antibiotics PT65845B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63456075A 1975-11-24 1975-11-24

Publications (2)

Publication Number Publication Date
PT65845A PT65845A (en) 1976-12-01
PT65845B true PT65845B (en) 1978-10-10

Family

ID=24544292

Family Applications (1)

Application Number Title Priority Date Filing Date
PT65845A PT65845B (en) 1975-11-24 1976-11-16 Process for the preparation of antibiotics

Country Status (16)

Country Link
JP (1) JPS5265295A (de)
AR (1) AR224224A1 (de)
AU (1) AU510252B2 (de)
BE (1) BE848349A (de)
CH (1) CH625803A5 (de)
DE (1) DE2652678A1 (de)
DK (1) DK497476A (de)
ES (1) ES453508A1 (de)
FR (1) FR2351979A1 (de)
GB (1) GB1561108A (de)
GR (1) GR61407B (de)
HU (1) HU175266B (de)
NL (1) NL7612932A (de)
PT (1) PT65845B (de)
SE (1) SE7612295L (de)
ZA (1) ZA766986B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7800978L (sv) * 1977-02-11 1978-08-12 Merck & Co Inc Antibiotikum
SE7800979L (sv) * 1977-02-11 1978-08-12 Merck & Co Inc Antibiotikum
US4162193A (en) * 1977-08-19 1979-07-24 Merck & Co., Inc. Enzymatic cleavage of N-acyl-thienamycins
PH16708A (en) 1978-07-24 1984-01-20 Merck & Co Inc Z-2-acylamino-3-monosubstituted propenoates
ATE4224T1 (de) * 1979-08-28 1983-08-15 Merck & Co. Inc. Verfahren zur reinigung von thienamycin.
DE3146190A1 (de) * 1981-11-21 1983-06-16 Hoechst Ag, 6230 Frankfurt Isolierung von chemisch instabilen antibiotika aus fermentationsloesungen
US10695322B2 (en) 2016-01-29 2020-06-30 The Johns Hopkins University Inhibitors of bacterial growth

Also Published As

Publication number Publication date
JPS5265295A (en) 1977-05-30
HU175266B (hu) 1980-06-28
FR2351979B1 (de) 1982-08-13
ZA766986B (en) 1978-06-28
AU510252B2 (en) 1980-06-19
BE848349A (fr) 1977-05-16
PT65845A (en) 1976-12-01
AR224224A1 (es) 1981-11-13
GB1561108A (en) 1980-02-13
AU1964576A (en) 1978-05-25
CH625803A5 (en) 1981-10-15
GR61407B (en) 1978-11-11
DE2652678A1 (de) 1977-06-02
FR2351979A1 (fr) 1977-12-16
NL7612932A (nl) 1977-05-26
SE7612295L (sv) 1977-05-25
ES453508A1 (es) 1978-03-01
DK497476A (da) 1977-05-25

Similar Documents

Publication Publication Date Title
GB1547802A (en) Process for the preparation of poly-phenyleneterephthalamide
IL50787A (en) Process for the preparation of corticoids
GB1517423A (en) Process for the preparation of diaryl-carbonates
PT65486B (en) Process for the preparation of carbonil-substituted 1-sulfonylbenzimidazoles
GR61674B (en) Preparation process of antibiotics
GB1535291A (en) Process for the preparation of amoxycillin
PT65036A (en) Process for the preparation of n-aryl-anthranilic acids
PT64878A (en) Process for the preparation of new indolylalkylpiperidines
PT65255B (en) Process for the preparation of 11-desoxy-16-aryloxy-w-tetranorprostaglandins
CH608786A5 (en) Process for the preparation of acetoacetylarylamides
GR59308B (en) New preparation process of antibiotics
GB1534077A (en) Process for the preparation of 5-acetoacetylamino-benzimidazolone
PT64836B (en) Process for the preparation of novel antibiotic substancesderived from antibiotic 67-694
PT65845A (en) Process for the preparation of antibiotics
GB1552658A (en) Process for the preparation of s substituted phosphorodichloridothiolates
PT64983B (en) Process for the preparation of amino-acids
GB1520330A (en) Process for the preparation of phospholene-1-oxides or su-lphides
PT65120A (en) Process for the preparation of novel diureide derivatives
ZA763221B (en) Process for the preparation of 3-bromobenzalidehyde
PT65821B (en) Process for the preparation of novel d-homosteroids
PT64816B (en) Process for the preparation of aminocyclitol antibiotics
PT65176B (en) Process for the preparation of 6-aminomethylated 3-oxygenated cholest-5-enes
PT65357A (en) Process for the preparation of gammapyrones
IL49951A (en) Process for the preparation of htioglycols
GR61655B (en) Process for the preparation of broad spectrum antibiotics