PT65513A - Heteroarylbenzoxepin-acetic acids,precursors and derivatives thereof - Google Patents
Heteroarylbenzoxepin-acetic acids,precursors and derivatives thereofInfo
- Publication number
- PT65513A PT65513A PT65513A PT6551376A PT65513A PT 65513 A PT65513 A PT 65513A PT 65513 A PT65513 A PT 65513A PT 6551376 A PT6551376 A PT 6551376A PT 65513 A PT65513 A PT 65513A
- Authority
- PT
- Portugal
- Prior art keywords
- heteroarylbenzoxepin
- precursors
- derivatives
- acetic acids
- acetic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
- Pyrrole Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/607,926 US4025640A (en) | 1975-08-26 | 1975-08-26 | Oxothienobenzoxepin-acetic acids, precursors and derivatives thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT65513A true PT65513A (en) | 1976-09-01 |
| PT65513B PT65513B (en) | 1978-05-10 |
Family
ID=24434282
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT65513A PT65513B (en) | 1975-08-26 | 1976-08-25 | Heteroary benzoxepin-acetic acids precursors and derivatives thereof |
Country Status (25)
| Country | Link |
|---|---|
| US (7) | US4025640A (pt) |
| JP (1) | JPS5227764A (pt) |
| AT (1) | AT359505B (pt) |
| AU (1) | AU504461B2 (pt) |
| BE (1) | BE845551A (pt) |
| CA (1) | CA1068275A (pt) |
| CH (1) | CH624408A5 (pt) |
| DE (1) | DE2637110C3 (pt) |
| DK (1) | DK384576A (pt) |
| ES (1) | ES450881A1 (pt) |
| FI (1) | FI62093C (pt) |
| FR (2) | FR2346004A1 (pt) |
| GB (2) | GB1563841A (pt) |
| GR (1) | GR60832B (pt) |
| HU (2) | HU174164B (pt) |
| IE (1) | IE43940B1 (pt) |
| IL (2) | IL50347A (pt) |
| IT (1) | IT1064977B (pt) |
| LU (1) | LU75650A1 (pt) |
| MX (1) | MX4236E (pt) |
| NL (1) | NL7609292A (pt) |
| NO (1) | NO145139C (pt) |
| PT (1) | PT65513B (pt) |
| SE (1) | SE430161B (pt) |
| ZA (1) | ZA765112B (pt) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4025640A (en) * | 1975-08-26 | 1977-05-24 | American Hoechst Corporation | Oxothienobenzoxepin-acetic acids, precursors and derivatives thereof |
| US4104280A (en) * | 1977-02-04 | 1978-08-01 | Syntex (U.S.A.) Inc. | Dibenzo [b.f]thiepin and dibenzo[b.f]oxepin derivatives |
| US4130654A (en) * | 1978-01-30 | 1978-12-19 | Syntex (U.S.A.) Inc. | Novel 4-(8X-6,11-dihydrodibenzo-[b.e.]-thiepin-11-one-3-yl)-4-oxobutyric acids, methods of preparation, compositions and uses thereof |
| JPS54115388A (en) * | 1978-03-01 | 1979-09-07 | Nippon Chemiphar Co Ltd | Acetic acid derivative and its preparation |
| JPS54147304U (pt) * | 1978-04-04 | 1979-10-13 | ||
| US4211877A (en) * | 1979-02-13 | 1980-07-08 | American Hoechst Corporation | Method of preparation of isopropyl 4,10-dihydro-10-oxothieno[3,2-c][1]benzoxepin-8-acetate |
| DE3125374A1 (de) * | 1981-06-27 | 1983-01-13 | Hoechst Ag, 6000 Frankfurt | Verfahren zur herstellung von heteroaryl- und dibenzoxepinalkansaeuren |
| AU8509882A (en) * | 1981-06-30 | 1983-01-06 | Merck & Co., Inc. | Tricyclic derivatives of substituted pyrrole acids |
| US4560701A (en) * | 1981-07-23 | 1985-12-24 | Hoechst-Roussel Pharmaceuticals Inc. | Oxothienobenzoxepins, medicinal use, and process for the preparation thereof |
| US4496580A (en) * | 1981-07-23 | 1985-01-29 | Hoechst-Roussel Pharmaceuticals Inc. | Oxothienobenzoxepins |
| US4477465A (en) * | 1983-03-10 | 1984-10-16 | Hoechst-Roussel Pharmaceuticals Inc. | Substituted 4,10-dihydro-10-oxothieno benzoxepins |
| US4514411A (en) * | 1983-03-10 | 1985-04-30 | Hoechst-Roussel Pharmaceuticals Inc. | Substituted 4,10-dihydro-10-oxothieno benzoxepins |
| US4751238A (en) * | 1983-03-10 | 1988-06-14 | Hoechst-Roussel Pharmaceuticals, Inc. | Substituted alkyl amine derivatives of 6,11-dihydro-11-oxodibenz[b,e]oxepins |
| EP0118867A3 (en) * | 1983-03-10 | 1984-12-05 | Hoechst-Roussel Pharmaceuticals Incorporated | Substituted 4,10-dihydro-10-oxothieno benzoxepins, a method of preparing the same and intermediate thereof and their use as medicaments |
| US5260319A (en) * | 1989-12-26 | 1993-11-09 | Hoechst-Roussel Pharmaceuticals Incorporated | Thienobenzoxepins and naphthothiophenes |
| US5139796A (en) * | 1991-06-28 | 1992-08-18 | Wm. Wrigley Jr. Company | Tocopherol mixture for use as a mint oil antioxidant in chewing gum |
| US5200213A (en) * | 1991-08-12 | 1993-04-06 | Wm. Wrigley Jr. Company | Gum base containing tocopherol |
| US5132121A (en) * | 1991-08-12 | 1992-07-21 | Wm. Wrigley Jr. Company | Gum base containing tocopherol |
| EP1554572B1 (en) | 2001-07-25 | 2009-10-14 | Raptor Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
| EP3827747A1 (en) | 2005-04-28 | 2021-06-02 | Otsuka Pharmaceutical Co., Ltd. | Pharma-informatics system |
| EP2063905B1 (en) | 2006-09-18 | 2014-07-30 | Raptor Pharmaceutical Inc | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
| NZ616673A (en) | 2009-02-20 | 2014-08-29 | To Bbb Holding B V | Glutathione-based drug delivery system |
| ES2942923T3 (es) | 2009-05-06 | 2023-06-07 | Laboratory Skin Care Inc | Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH83A (fr) * | 1888-11-17 | 1889-01-10 | Fontainemelon Horlogerie | Perfectionnements apportés à la construction des montres de tous calibres |
| CH469729A (de) * | 1963-08-31 | 1969-03-15 | Spofa Vereinigte Pharma Werke | Verfahren zur Herstellung von neuen 4,9-Dihydrothieno-(2,3-b)-benzo-(e)-thiepinderivaten |
| US3883551A (en) * | 1969-08-25 | 1975-05-13 | Little Inc A | Thienobenzopyrans and thiopyranobenzopyrans |
| US3888946A (en) * | 1971-03-17 | 1975-06-10 | Little Inc A | Pyrano benzopyrans |
| US3960871A (en) * | 1971-12-27 | 1976-06-01 | Sharps Associates | Esters of thienobenzopyrans and thiopyranobenzopyrans |
| US3991194A (en) * | 1971-12-27 | 1976-11-09 | Sharps Associates | Heterocyclic esters of benzopyranopyridines |
| DK131631C (da) * | 1972-04-07 | 1976-01-12 | Sandoz Ag | Analogifremgangsmade til fremstilling af 4-oxo-benzo(4,5)cyclohepta(1,2-b)thiophen-2-eddikesyreforbindelser |
| GB1403487A (en) * | 1972-07-21 | 1975-08-28 | Yoshitomi Pharmaceutical | Heterocyclic substituted alkanoic acids and derivatives |
| US3825574A (en) * | 1972-12-04 | 1974-07-23 | Warner Lambert Co | Process for preparing substituted chromone-3-carbonitriles,carboxamides and carboxylic acids |
| US3862143A (en) * | 1972-12-04 | 1975-01-21 | Warner Lambert Co | Substituted chromone-3-carbonitriles, carboxamides and carboxylic acids |
| US3895034A (en) * | 1973-08-29 | 1975-07-15 | Sharps Ass | 1 OR 2-Mono and dialkyl substituted thienobenzopyrans |
| US3946111A (en) * | 1973-08-29 | 1976-03-23 | Sharps Associates | Pharmaceutical compositions containing 1 or 2-mono and dialkyl substituted thienobenzopyrans and pharmacological uses thereof |
| FR2242098B1 (pt) * | 1973-09-04 | 1978-07-28 | Yoshitomi Pharmaceutical | |
| FI258574A (pt) * | 1973-09-13 | 1975-03-14 | Sandoz Ag | |
| US3952025A (en) * | 1974-08-26 | 1976-04-20 | American Hoechst Corporation | Substituted 2-phenyl-4,6,7,8-tetrahydrofuro and 1,4,5,6,7,8-hexahydropyrrolo[3,2,-c]azepines |
| US4025640A (en) * | 1975-08-26 | 1977-05-24 | American Hoechst Corporation | Oxothienobenzoxepin-acetic acids, precursors and derivatives thereof |
| US4028383A (en) * | 1975-09-08 | 1977-06-07 | Warner-Lambert Company | Indolopyrones having antiallergic activity |
-
1975
- 1975-08-26 US US05/607,926 patent/US4025640A/en not_active Expired - Lifetime
-
1976
- 1976-08-18 DE DE2637110A patent/DE2637110C3/de not_active Expired
- 1976-08-20 NL NL7609292A patent/NL7609292A/xx not_active Application Discontinuation
- 1976-08-20 ES ES450881A patent/ES450881A1/es not_active Expired
- 1976-08-23 CH CH1067076A patent/CH624408A5/de not_active IP Right Cessation
- 1976-08-24 IT IT26507/76A patent/IT1064977B/it active
- 1976-08-24 IL IL50347A patent/IL50347A/xx unknown
- 1976-08-24 FI FI762422A patent/FI62093C/fi not_active IP Right Cessation
- 1976-08-24 LU LU75650A patent/LU75650A1/xx unknown
- 1976-08-24 GR GR51534A patent/GR60832B/el unknown
- 1976-08-25 PT PT65513A patent/PT65513B/pt unknown
- 1976-08-25 MX MX764855U patent/MX4236E/es unknown
- 1976-08-25 AT AT630876A patent/AT359505B/de not_active IP Right Cessation
- 1976-08-25 IE IE1895/76A patent/IE43940B1/en unknown
- 1976-08-25 SE SE7609390A patent/SE430161B/xx unknown
- 1976-08-25 CA CA259,785A patent/CA1068275A/en not_active Expired
- 1976-08-25 AU AU17151/76A patent/AU504461B2/en not_active Expired
- 1976-08-25 DK DK384576A patent/DK384576A/da not_active Application Discontinuation
- 1976-08-25 NO NO762929A patent/NO145139C/no unknown
- 1976-08-25 ZA ZA765112A patent/ZA765112B/xx unknown
- 1976-08-25 FR FR7625728A patent/FR2346004A1/fr active Granted
- 1976-08-26 HU HU76HO2082A patent/HU174164B/hu unknown
- 1976-08-26 JP JP51101181A patent/JPS5227764A/ja active Pending
- 1976-08-26 BE BE170106A patent/BE845551A/xx not_active IP Right Cessation
- 1976-08-26 GB GB35542/76A patent/GB1563841A/en not_active Expired
- 1976-08-26 GB GB12883/79A patent/GB1563842A/en not_active Expired
- 1976-08-26 HU HU76HO1923A patent/HU173465B/hu unknown
-
1977
- 1977-04-19 US US05/788,786 patent/US4117152A/en not_active Expired - Lifetime
- 1977-04-19 US US05/788,787 patent/US4107321A/en not_active Expired - Lifetime
- 1977-04-19 US US05/788,782 patent/US4124713A/en not_active Expired - Lifetime
- 1977-04-19 US US05/788,958 patent/US4107177A/en not_active Expired - Lifetime
- 1977-04-19 US US05/788,753 patent/US4081457A/en not_active Expired - Lifetime
- 1977-04-19 US US05/788,788 patent/US4101559A/en not_active Expired - Lifetime
- 1977-05-18 FR FR7715359A patent/FR2351972A1/fr active Granted
-
1979
- 1979-12-04 IL IL58864A patent/IL58864A0/xx unknown
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