PT4385509T - Regime de dosagem de migalastat tendo farmacocinética melhorada - Google Patents

Regime de dosagem de migalastat tendo farmacocinética melhorada

Info

Publication number
PT4385509T
PT4385509T PT231763665T PT23176366T PT4385509T PT 4385509 T PT4385509 T PT 4385509T PT 231763665 T PT231763665 T PT 231763665T PT 23176366 T PT23176366 T PT 23176366T PT 4385509 T PT4385509 T PT 4385509T
Authority
PT
Portugal
Prior art keywords
migalastat
formulations
improved pharmacokinetics
pharmacokinetics
improved
Prior art date
Application number
PT231763665T
Other languages
English (en)
Portuguese (pt)
Original Assignee
Amicus Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amicus Therapeutics Inc filed Critical Amicus Therapeutics Inc
Publication of PT4385509T publication Critical patent/PT4385509T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • A61K31/522Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
PT231763665T 2022-12-13 2023-05-31 Regime de dosagem de migalastat tendo farmacocinética melhorada PT4385509T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202263432235P 2022-12-13 2022-12-13
US18/315,928 US20240197706A1 (en) 2022-12-13 2023-05-11 Methods of improving the pharmacokinetics of migalastat

Publications (1)

Publication Number Publication Date
PT4385509T true PT4385509T (pt) 2025-11-25

Family

ID=86646511

Family Applications (1)

Application Number Title Priority Date Filing Date
PT231763665T PT4385509T (pt) 2022-12-13 2023-05-31 Regime de dosagem de migalastat tendo farmacocinética melhorada

Country Status (16)

Country Link
US (1) US20240197706A1 (enExample)
EP (2) EP4667050A2 (enExample)
JP (1) JP7757345B2 (enExample)
KR (1) KR20240094973A (enExample)
AU (1) AU2023396459A1 (enExample)
CA (1) CA3201512A1 (enExample)
CL (1) CL2025001743A1 (enExample)
CO (1) CO2025009079A2 (enExample)
DE (1) DE202023003007U1 (enExample)
DK (1) DK4385509T3 (enExample)
FI (1) FI4385509T3 (enExample)
IL (1) IL321404A (enExample)
MX (1) MX2025006897A (enExample)
PT (1) PT4385509T (enExample)
TW (1) TW202423436A (enExample)
WO (1) WO2024129220A1 (enExample)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6274597B1 (en) 1998-06-01 2001-08-14 Mount Sinai School Of Medicine Of New York University Method of enhancing lysosomal α-Galactosidase A
JP2010523578A (ja) 2007-03-30 2010-07-15 アミカス セラピューティックス インコーポレイテッド 薬理シャペロンを用いるファブリー病の治療方法
US9999618B2 (en) * 2007-04-26 2018-06-19 Amicus Therapeutics, Inc. Dosing regimens for the treatment of lysosomal storage diseases using pharmacological chaperones
SI2252313T1 (sl) 2008-02-12 2015-08-31 Amicus Therapeutics, Inc. Postopek napovedovanja odgovora na zdravljenje bolezni s farmakološkim spremljevalcem
EA031874B1 (ru) * 2011-03-11 2019-03-29 Амикус Терапьютикс, Инк. Способ лечения болезни фабри
US20250144240A1 (en) * 2021-11-03 2025-05-08 Sangamo Therapeutics, Inc. Methods for use of viral vector constructs for the treatment of fabry disease

Also Published As

Publication number Publication date
KR20240094973A (ko) 2024-06-25
MX2025006897A (es) 2025-07-01
WO2024129220A1 (en) 2024-06-20
IL321404A (en) 2025-08-01
CO2025009079A2 (es) 2025-09-29
TW202423436A (zh) 2024-06-16
DK4385509T3 (da) 2025-12-08
CA3201512A1 (en) 2024-06-13
JP7757345B2 (ja) 2025-10-21
JP2024084670A (ja) 2024-06-25
US20240197706A1 (en) 2024-06-20
DE202023003007U1 (de) 2025-07-21
EP4385509B1 (en) 2025-09-03
AU2023396459A1 (en) 2025-06-26
EP4385509A1 (en) 2024-06-19
FI4385509T3 (fi) 2025-12-05
CL2025001743A1 (es) 2025-10-03
EP4667050A2 (en) 2025-12-24

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