CL2025001743A1 - Procedimientos para mejorar la farmacocinética de migalastat - Google Patents

Procedimientos para mejorar la farmacocinética de migalastat

Info

Publication number
CL2025001743A1
CL2025001743A1 CL2025001743A CL2025001743A CL2025001743A1 CL 2025001743 A1 CL2025001743 A1 CL 2025001743A1 CL 2025001743 A CL2025001743 A CL 2025001743A CL 2025001743 A CL2025001743 A CL 2025001743A CL 2025001743 A1 CL2025001743 A1 CL 2025001743A1
Authority
CL
Chile
Prior art keywords
migalastat
pharmacokinetics
procedures
improve
limiting
Prior art date
Application number
CL2025001743A
Other languages
English (en)
Spanish (es)
Inventor
Johnson Franklin
Original Assignee
Amicus Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amicus Therapeutics Inc filed Critical Amicus Therapeutics Inc
Publication of CL2025001743A1 publication Critical patent/CL2025001743A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • A61K31/522Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CL2025001743A 2022-12-13 2025-06-12 Procedimientos para mejorar la farmacocinética de migalastat CL2025001743A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202263432235P 2022-12-13 2022-12-13
US18/315,928 US20240197706A1 (en) 2022-12-13 2023-05-11 Methods of improving the pharmacokinetics of migalastat

Publications (1)

Publication Number Publication Date
CL2025001743A1 true CL2025001743A1 (es) 2025-10-03

Family

ID=86646511

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2025001743A CL2025001743A1 (es) 2022-12-13 2025-06-12 Procedimientos para mejorar la farmacocinética de migalastat

Country Status (16)

Country Link
US (1) US20240197706A1 (enExample)
EP (1) EP4385509B1 (enExample)
JP (1) JP7757345B2 (enExample)
KR (1) KR20240094973A (enExample)
AU (1) AU2023396459A1 (enExample)
CA (1) CA3201512A1 (enExample)
CL (1) CL2025001743A1 (enExample)
CO (1) CO2025009079A2 (enExample)
DE (1) DE202023003007U1 (enExample)
DK (1) DK4385509T3 (enExample)
FI (1) FI4385509T3 (enExample)
IL (1) IL321404A (enExample)
MX (1) MX2025006897A (enExample)
PT (1) PT4385509T (enExample)
TW (1) TW202423436A (enExample)
WO (1) WO2024129220A1 (enExample)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6274597B1 (en) 1998-06-01 2001-08-14 Mount Sinai School Of Medicine Of New York University Method of enhancing lysosomal α-Galactosidase A
US20100113517A1 (en) 2007-03-30 2010-05-06 Amicus Therapeutics, Inc. Method for the treatment of fabry disease using pharmacological chaperones
US9999618B2 (en) * 2007-04-26 2018-06-19 Amicus Therapeutics, Inc. Dosing regimens for the treatment of lysosomal storage diseases using pharmacological chaperones
AU2009214648B2 (en) 2008-02-12 2014-11-13 Amicus Therapeutics, Inc. Method to predict response to pharmacological chaperone treatment of diseases
CN107088225A (zh) * 2011-03-11 2017-08-25 阿米库斯治疗学公司 治疗法布里病的给药方案
US20250144240A1 (en) * 2021-11-03 2025-05-08 Sangamo Therapeutics, Inc. Methods for use of viral vector constructs for the treatment of fabry disease

Also Published As

Publication number Publication date
MX2025006897A (es) 2025-07-01
CO2025009079A2 (es) 2025-09-29
US20240197706A1 (en) 2024-06-20
IL321404A (en) 2025-08-01
WO2024129220A1 (en) 2024-06-20
FI4385509T3 (fi) 2025-12-05
AU2023396459A1 (en) 2025-06-26
DK4385509T3 (da) 2025-12-08
CA3201512A1 (en) 2024-06-13
EP4385509B1 (en) 2025-09-03
KR20240094973A (ko) 2024-06-25
JP2024084670A (ja) 2024-06-25
DE202023003007U1 (de) 2025-07-21
EP4385509A1 (en) 2024-06-19
PT4385509T (pt) 2025-11-25
TW202423436A (zh) 2024-06-16
JP7757345B2 (ja) 2025-10-21

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