CO2025009079A2 - Procedimientos para mejorar la farmacocinética de migalastat - Google Patents

Procedimientos para mejorar la farmacocinética de migalastat

Info

Publication number
CO2025009079A2
CO2025009079A2 CONC2025/0009079A CO2025009079A CO2025009079A2 CO 2025009079 A2 CO2025009079 A2 CO 2025009079A2 CO 2025009079 A CO2025009079 A CO 2025009079A CO 2025009079 A2 CO2025009079 A2 CO 2025009079A2
Authority
CO
Colombia
Prior art keywords
migalastat
pharmacokinetics
procedures
improve
limiting
Prior art date
Application number
CONC2025/0009079A
Other languages
English (en)
Spanish (es)
Inventor
Franklin Johnson
Original Assignee
Amicus Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amicus Therapeutics Inc filed Critical Amicus Therapeutics Inc
Publication of CO2025009079A2 publication Critical patent/CO2025009079A2/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • A61K31/522Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CONC2025/0009079A 2022-12-13 2025-07-03 Procedimientos para mejorar la farmacocinética de migalastat CO2025009079A2 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263432235P 2022-12-13 2022-12-13
US18/315,928 US20240197706A1 (en) 2022-12-13 2023-05-11 Methods of improving the pharmacokinetics of migalastat
PCT/US2023/067656 WO2024129220A1 (en) 2022-12-13 2023-05-31 Methods of improving the pharmacokinetics of migalastat

Publications (1)

Publication Number Publication Date
CO2025009079A2 true CO2025009079A2 (es) 2025-09-29

Family

ID=86646511

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2025/0009079A CO2025009079A2 (es) 2022-12-13 2025-07-03 Procedimientos para mejorar la farmacocinética de migalastat

Country Status (16)

Country Link
US (1) US20240197706A1 (enExample)
EP (2) EP4667050A2 (enExample)
JP (1) JP7757345B2 (enExample)
KR (1) KR20240094973A (enExample)
AU (1) AU2023396459A1 (enExample)
CA (1) CA3201512A1 (enExample)
CL (1) CL2025001743A1 (enExample)
CO (1) CO2025009079A2 (enExample)
DE (1) DE202023003007U1 (enExample)
DK (1) DK4385509T3 (enExample)
FI (1) FI4385509T3 (enExample)
IL (1) IL321404A (enExample)
MX (1) MX2025006897A (enExample)
PT (1) PT4385509T (enExample)
TW (1) TW202423436A (enExample)
WO (1) WO2024129220A1 (enExample)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6274597B1 (en) 1998-06-01 2001-08-14 Mount Sinai School Of Medicine Of New York University Method of enhancing lysosomal α-Galactosidase A
AU2008232614A1 (en) 2007-03-30 2008-10-09 Amicus Therapeutics, Inc. Method for the treatment of Fabry disease using pharmacological chaperones
US9999618B2 (en) * 2007-04-26 2018-06-19 Amicus Therapeutics, Inc. Dosing regimens for the treatment of lysosomal storage diseases using pharmacological chaperones
DK3470077T3 (da) 2008-02-12 2020-11-30 Amicus Therapeutics Inc Fremgangsmåde til forudsigelse af respons på behandling af sygdomme med farmakologiske chaperoner
SG193379A1 (en) * 2011-03-11 2013-10-30 Amicus Therapeutics Inc Dosing regimens for the treatment of fabry disease
WO2023081781A1 (en) * 2021-11-03 2023-05-11 Sangamo Therapeutics, Inc. Methods for use of viral vector constructs for the treatment of fabry disease

Also Published As

Publication number Publication date
JP7757345B2 (ja) 2025-10-21
JP2024084670A (ja) 2024-06-25
DE202023003007U1 (de) 2025-07-21
US20240197706A1 (en) 2024-06-20
MX2025006897A (es) 2025-07-01
CL2025001743A1 (es) 2025-10-03
KR20240094973A (ko) 2024-06-25
TW202423436A (zh) 2024-06-16
CA3201512A1 (en) 2024-06-13
FI4385509T3 (fi) 2025-12-05
WO2024129220A1 (en) 2024-06-20
AU2023396459A1 (en) 2025-06-26
DK4385509T3 (da) 2025-12-08
EP4385509B1 (en) 2025-09-03
EP4385509A1 (en) 2024-06-19
PT4385509T (pt) 2025-11-25
EP4667050A2 (en) 2025-12-24
IL321404A (en) 2025-08-01

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