PT3589728T - Células assassinas naturais - Google Patents
Células assassinas naturaisInfo
- Publication number
- PT3589728T PT3589728T PT187101258T PT18710125T PT3589728T PT 3589728 T PT3589728 T PT 3589728T PT 187101258 T PT187101258 T PT 187101258T PT 18710125 T PT18710125 T PT 18710125T PT 3589728 T PT3589728 T PT 3589728T
- Authority
- PT
- Portugal
- Prior art keywords
- natural killer
- killer cells
- cells
- natural
- killer
- Prior art date
Links
- 210000000822 natural killer cell Anatomy 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0646—Natural killers cells [NK], NKT cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/999—Small molecules not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Hematology (AREA)
- General Engineering & Computer Science (AREA)
- Developmental Biology & Embryology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1703476.0A GB201703476D0 (en) | 2017-03-03 | 2017-03-03 | Natural killer cells |
Publications (1)
Publication Number | Publication Date |
---|---|
PT3589728T true PT3589728T (pt) | 2022-09-16 |
Family
ID=58544022
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT187101258T PT3589728T (pt) | 2017-03-03 | 2018-03-02 | Células assassinas naturais |
Country Status (8)
Country | Link |
---|---|
US (2) | US11559547B2 (pt) |
EP (2) | EP3589728B1 (pt) |
JP (2) | JP7225107B2 (pt) |
DK (1) | DK3589728T3 (pt) |
ES (1) | ES2928879T3 (pt) |
GB (1) | GB201703476D0 (pt) |
PT (1) | PT3589728T (pt) |
WO (1) | WO2018158587A1 (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201810486D0 (en) * | 2018-06-26 | 2018-08-08 | Imperial Innovations Ltd | Natural killer cells |
CN114907333B (zh) * | 2022-05-11 | 2023-07-04 | 中国人民解放军军事科学院军事医学研究院 | 环丙甲酰胺衍生物及其制备方法和用途 |
WO2024047368A1 (en) * | 2022-09-02 | 2024-03-07 | Imperial College Innovations Limited | Natural killer cells |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9121008B2 (en) | 2005-08-31 | 2015-09-01 | University Of Utah Research Foundation | Development of natural killer cells and functional natural killer cell lines |
ES2627910T3 (es) * | 2009-12-29 | 2017-08-01 | Gamida-Cell Ltd. | Métodos para potenciar la proliferación y la actividad de células destructoras naturales |
US11118165B2 (en) | 2011-03-18 | 2021-09-14 | Glycostem Therapeutics B.V. | Generation of NK cells and NK-cell progenitors |
WO2013033310A1 (en) * | 2011-08-31 | 2013-03-07 | Theodore Mark Kamenecka | Modulators of rev-erb |
ITTO20130816A1 (it) * | 2013-10-09 | 2015-04-10 | Fond Istituto Italiano Di Tecnologia | Antagonisti di rev-erb diarilalchilaminici e loro uso come farmaci |
WO2015103527A1 (en) | 2014-01-06 | 2015-07-09 | The Scripps Research Institute | Modulators of rev-erb |
CN105596336B (zh) | 2016-01-18 | 2018-05-22 | 暨南大学 | 化合物sr8278在制备治疗i型糖尿病角膜病变药物中的应用 |
US20180280372A1 (en) * | 2016-11-22 | 2018-10-04 | Washington University | Compositions and methods for inhibiting autophagy and contraception |
GB201704953D0 (en) | 2017-03-28 | 2017-05-10 | Imp Innovations Ltd | Natural killer cells |
GB201810486D0 (en) | 2018-06-26 | 2018-08-08 | Imperial Innovations Ltd | Natural killer cells |
-
2017
- 2017-03-03 GB GBGB1703476.0A patent/GB201703476D0/en not_active Ceased
-
2018
- 2018-03-02 WO PCT/GB2018/050542 patent/WO2018158587A1/en active Application Filing
- 2018-03-02 ES ES18710125T patent/ES2928879T3/es active Active
- 2018-03-02 EP EP18710125.8A patent/EP3589728B1/en active Active
- 2018-03-02 JP JP2019547262A patent/JP7225107B2/ja active Active
- 2018-03-02 EP EP22188145.1A patent/EP4137563A1/en active Pending
- 2018-03-02 US US16/490,258 patent/US11559547B2/en active Active
- 2018-03-02 DK DK18710125.8T patent/DK3589728T3/da active
- 2018-03-02 PT PT187101258T patent/PT3589728T/pt unknown
-
2022
- 2022-12-05 JP JP2022194045A patent/JP2023025190A/ja active Pending
-
2023
- 2023-01-10 US US18/152,563 patent/US20230330145A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2020510431A (ja) | 2020-04-09 |
JP2023025190A (ja) | 2023-02-21 |
EP3589728B1 (en) | 2022-09-07 |
ES2928879T3 (es) | 2022-11-23 |
US20230330145A1 (en) | 2023-10-19 |
DK3589728T3 (da) | 2022-09-19 |
EP3589728A1 (en) | 2020-01-08 |
US11559547B2 (en) | 2023-01-24 |
GB201703476D0 (en) | 2017-04-19 |
US20190381102A1 (en) | 2019-12-19 |
WO2018158587A1 (en) | 2018-09-07 |
EP4137563A1 (en) | 2023-02-22 |
JP7225107B2 (ja) | 2023-02-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1245080A1 (zh) | 自然殺傷細胞的方法和組合物 | |
IL253248A0 (en) | Natural killer cells and their uses | |
IL258666A (en) | Natural killer cells and ilc3 cells and their use | |
HK1252582A1 (zh) | 具有增强的細胞毒性的修飾的天然殺傷細胞和天然殺傷細胞系 | |
EP3562492A4 (en) | GENETICALLY MODIFIED NATURAL KILLER CELLS | |
SG11201609118RA (en) | Modified natural killer cells and uses thereof | |
IL273915A (en) | cell | |
GB201712733D0 (en) | Methods & cells | |
GB201713078D0 (en) | T Cell Modification | |
GB201707783D0 (en) | Cell | |
GB201707779D0 (en) | Cell | |
GB201704953D0 (en) | Natural killer cells | |
GB201720949D0 (en) | Cell | |
ZA201900891B (en) | B-cell-mimetic cells | |
GB201718697D0 (en) | Cell | |
PT3589728T (pt) | Células assassinas naturais | |
GB201810486D0 (en) | Natural killer cells | |
HK1259030A1 (zh) | 具有抗趨除特性的修飾的天然殺傷細胞及其用途 | |
GB201714718D0 (en) | Cell | |
GB201615741D0 (en) | Artificial cells | |
GB201720344D0 (en) | Cell | |
GB201720343D0 (en) | Cell | |
GB201712407D0 (en) | Cell | |
GB201707780D0 (en) | Cell | |
GB201707782D0 (en) | Cell |