PT3459955T - Método e aplicação inovadores de porfirinas e cloros não simetricamente meso-substituídos para pdt - Google Patents

Método e aplicação inovadores de porfirinas e cloros não simetricamente meso-substituídos para pdt

Info

Publication number
PT3459955T
PT3459955T PT182021279T PT18202127T PT3459955T PT 3459955 T PT3459955 T PT 3459955T PT 182021279 T PT182021279 T PT 182021279T PT 18202127 T PT18202127 T PT 18202127T PT 3459955 T PT3459955 T PT 3459955T
Authority
PT
Portugal
Prior art keywords
unsymmetrically
chlorins
pdt
meso
application
Prior art date
Application number
PT182021279T
Other languages
English (en)
Original Assignee
Biolitec Unternehmensberatungs Ii Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biolitec Unternehmensberatungs Ii Ag filed Critical Biolitec Unternehmensberatungs Ii Ag
Publication of PT3459955T publication Critical patent/PT3459955T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
PT182021279T 2008-09-18 2009-09-17 Método e aplicação inovadores de porfirinas e cloros não simetricamente meso-substituídos para pdt PT3459955T (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US9802608P 2008-09-18 2008-09-18
PCT/US2009/057283 WO2010033678A2 (en) 2008-09-18 2009-09-17 Novel method and application of unsymmetrically meso-substituted porphyrins and chlorins for pdt
EP18202127.9A EP3459955B1 (en) 2008-09-18 2009-09-17 Novel method and application of unsymmetrically meso-substituted porphyrins and chlorins for pdt
EP09815180.6A EP2350058B1 (en) 2008-09-18 2009-09-17 Novel method and application of unsymmetrically meso-substituted porphyrins and chlorins for pdt

Publications (1)

Publication Number Publication Date
PT3459955T true PT3459955T (pt) 2022-11-29

Family

ID=42040129

Family Applications (1)

Application Number Title Priority Date Filing Date
PT182021279T PT3459955T (pt) 2008-09-18 2009-09-17 Método e aplicação inovadores de porfirinas e cloros não simetricamente meso-substituídos para pdt

Country Status (8)

Country Link
US (1) US9315510B2 (pt)
EP (2) EP2350058B1 (pt)
JP (1) JP5955559B2 (pt)
CN (1) CN102159569B (pt)
ES (2) ES2932287T3 (pt)
PT (1) PT3459955T (pt)
RU (1) RU2574062C9 (pt)
WO (1) WO2010033678A2 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013015774A1 (en) 2011-07-22 2013-01-31 Biolitec Pharma Marketing Ltd Glyco-substituted dihydroxy-chlorins and b-functionalized chlorins for anti-microbial photodynamic therapy
EP2870159B1 (en) * 2010-07-22 2017-06-28 biolitec Unternehmensbeteiligungs II AG APPLICATION OF ß-FUNCTIONALIZED DIHYDROXY-CHLORINS FOR PDT
BR112013001577B1 (pt) * 2010-07-22 2021-05-04 Biolitec Unternehmensbeteiligungs Ii Ag conjugados de carboidrato e dihidroxiclorina
CN102558187B (zh) * 2011-12-29 2014-02-26 东华大学 一种四氢卟吩类化合物及其制备和应用
US9045488B2 (en) * 2012-07-09 2015-06-02 Photolitec, Llc PAA nanoparticles for tumor treatment and imaging
CN103570732B (zh) * 2013-10-30 2016-06-08 东华大学 一种卟吩类化合物及其制备方法和应用
JP6589241B2 (ja) * 2013-12-18 2019-10-16 出光興産株式会社 化合物、有機エレクトロルミネッセンス素子用材料、インク組成物、有機エレクトロルミネッセンス素子、電子機器、及び化合物の製造方法
WO2016051361A1 (en) 2014-09-30 2016-04-07 Biolitec Unternehmensbeteiligungs Ii Ag Specifically meso-substituted porphyrins and chlorins for photodynamic therapy
EP3210626A1 (en) * 2016-02-26 2017-08-30 biolitec Unternehmensbeteiligungs II AG Conjugates of porphyrinoid photosensitizers and glycerol-based polymers for photodynamic therapy
EP3626268A1 (en) 2018-09-24 2020-03-25 Westfälische Wilhelms-Universität Münster Polymer-particle light-cleavable carrier systems for photodynamic therapy
LU101031B1 (en) * 2018-12-10 2020-06-10 Biolitec Unternehmensbeteiligungs Ii Ag Specifically glyco-substituted porphyrins and chlorins for photodynamic therapy
WO2020120474A1 (en) * 2018-12-10 2020-06-18 Universität Hamburg Specifically glyco-substituted porphyrins and chlorins for photodynamic therapy
JP2024514848A (ja) * 2021-04-07 2024-04-03 ノース カロライナ ステート ユニバーシティ ポルフィリン－ヒドロポルフィリン化合物、それを含む組成物、及びそれらの使用方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4656186A (en) 1985-04-30 1987-04-07 Nippon Petrochemicals Co., Ltd. Tetrapyrrole therapeutic agents
GB8805849D0 (en) 1988-03-11 1988-04-13 Efamol Holdings Porphyrins & cancer treatment
US5330741A (en) 1992-02-24 1994-07-19 The Regents Of The University Of California Long-wavelength water soluble chlorin photosensitizers useful for photodynamic therapy and diagnosis of tumors
FR2709491B1 (fr) * 1993-09-03 1995-10-27 Centre Nat Rech Scient Nouveaux dérivés de porphyrines et leurs applications notamment en thérapeutique.
US5648485A (en) * 1994-10-26 1997-07-15 University Of British Columbia β, β-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins
US5703230A (en) * 1994-12-02 1997-12-30 University Of British Columbia Meso-monoiodo-substituted tetramacrocyclic compounds and methods for making and using the same
AU4139600A (en) 1999-04-14 2000-11-14 University Of British Columbia, The 1,3-dipolar cycloadditions to polypyrrolic macrocycles
US7022843B1 (en) 1999-04-14 2006-04-04 The University Of British Columbia β,β′-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins
EP1294726A2 (en) * 2000-06-26 2003-03-26 Catalyst Biomedica Ltd Improvements in and relating to chromophores
FR2812637B1 (fr) * 2000-08-01 2002-10-25 Anulm Ass Nantaise Pour L Util Nouveaux composes derives de dihydroporphyrine et leurs applications
GB0121023D0 (en) * 2001-08-30 2001-10-24 Norwegian Radium Hospital Res Compound
DE10146970A1 (de) * 2001-09-24 2003-04-17 Karlsruhe Forschzent Selbstorganisierende Assemmblage aus Porphyrin-Molekülen
GB0130778D0 (en) * 2001-12-21 2002-02-06 Catalyst Biomedica Ltd Novel compounds
DE60328496D1 (en) 2002-06-27 2009-09-03 Health Research Inc Fluorinierte chlorin und bacteriochlorin photosensitizer für fotodynamische therapie
ITFI20020200A1 (it) * 2002-10-21 2004-04-22 Molteni & C Dei Flii Alitti S P A Societa L Porfirine meso-sostituite.
US6949581B2 (en) * 2003-03-21 2005-09-27 Ceramoptec Industries, Inc. Water-soluble mono-PEGylated tetrapyrrole derivatives for photodynamic therapy and method of production
US20050048109A1 (en) 2003-08-26 2005-03-03 Ceramoptec Industries, Inc. Non-polar photosensitizer formulations for photodynamic therapy
FR2877943B1 (fr) * 2004-11-16 2008-09-05 Univ De Coimbra Nouveaux derives de porphyrine, notamment chlorines et/ou bacteriochlorine, et leurs applications en therapie photodynamique
WO2013168246A1 (ja) 2012-05-09 2013-11-14 トヨタ自動車株式会社 運転支援装置

Also Published As

Publication number Publication date
RU2574062C2 (ru) 2016-02-10
CN102159569A (zh) 2011-08-17
EP2350058B1 (en) 2018-10-24
RU2574062C9 (ru) 2016-10-27
RU2011108837A (ru) 2012-10-27
US20110206613A1 (en) 2011-08-25
US9315510B2 (en) 2016-04-19
JP5955559B2 (ja) 2016-07-20
JP2012503006A (ja) 2012-02-02
ES2707228T3 (es) 2019-04-03
EP2350058A4 (en) 2013-11-20
EP3459955A1 (en) 2019-03-27
ES2932287T3 (es) 2023-01-17
WO2010033678A2 (en) 2010-03-25
EP3459955B1 (en) 2022-11-02
WO2010033678A8 (en) 2014-12-18
WO2010033678A3 (en) 2010-07-01
CN102159569B (zh) 2016-02-03
EP2350058A2 (en) 2011-08-03

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