PT3241840T - Inibição da sinalização de axl em terapêutica anti-metastática - Google Patents

Inibição da sinalização de axl em terapêutica anti-metastática

Info

Publication number
PT3241840T
PT3241840T PT171593346T PT17159334T PT3241840T PT 3241840 T PT3241840 T PT 3241840T PT 171593346 T PT171593346 T PT 171593346T PT 17159334 T PT17159334 T PT 17159334T PT 3241840 T PT3241840 T PT 3241840T
Authority
PT
Portugal
Prior art keywords
inhibition
axl signaling
metastatic therapy
metastatic
therapy
Prior art date
Application number
PT171593346T
Other languages
English (en)
Portuguese (pt)
Original Assignee
Univ Leland Stanford Junior
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Leland Stanford Junior filed Critical Univ Leland Stanford Junior
Publication of PT3241840T publication Critical patent/PT3241840T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/10—Protein-tyrosine kinases (2.7.10)
    • C12Y207/10001—Receptor protein-tyrosine kinase (2.7.10.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
PT171593346T 2010-01-22 2011-01-21 Inibição da sinalização de axl em terapêutica anti-metastática PT3241840T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33647810P 2010-01-22 2010-01-22

Publications (1)

Publication Number Publication Date
PT3241840T true PT3241840T (pt) 2022-10-13

Family

ID=44307615

Family Applications (2)

Application Number Title Priority Date Filing Date
PT171593346T PT3241840T (pt) 2010-01-22 2011-01-21 Inibição da sinalização de axl em terapêutica anti-metastática
PT117352641T PT2525824T (pt) 2010-01-22 2011-01-21 Inibição da sinalização de axl em terapêutica antimetastática

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT117352641T PT2525824T (pt) 2010-01-22 2011-01-21 Inibição da sinalização de axl em terapêutica antimetastática

Country Status (14)

Country Link
US (2) US8618254B2 (enExample)
EP (2) EP3241840B1 (enExample)
JP (1) JP5965322B2 (enExample)
KR (3) KR101951410B1 (enExample)
CN (2) CN107082805A (enExample)
AU (2) AU2011207381B2 (enExample)
BR (1) BR112012018022A2 (enExample)
CA (2) CA3056999A1 (enExample)
DK (2) DK2525824T3 (enExample)
ES (2) ES2928111T3 (enExample)
PT (2) PT3241840T (enExample)
RU (1) RU2556822C2 (enExample)
WO (1) WO2011091305A2 (enExample)
ZA (2) ZA201204866B (enExample)

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Also Published As

Publication number Publication date
ZA201307676B (en) 2015-09-30
EP3241840A2 (en) 2017-11-08
EP2525824A4 (en) 2013-11-13
RU2012136113A (ru) 2014-02-27
US20130017205A1 (en) 2013-01-17
DK3241840T3 (da) 2022-10-03
CA3056999A1 (en) 2011-07-28
DK2525824T3 (en) 2017-07-17
EP3241840A3 (en) 2018-02-07
AU2016213693A1 (en) 2016-08-25
JP5965322B2 (ja) 2016-08-03
EP2525824A2 (en) 2012-11-28
JP2013518055A (ja) 2013-05-20
ES2928111T3 (es) 2022-11-15
WO2011091305A2 (en) 2011-07-28
CN107082805A (zh) 2017-08-22
HK1245806A1 (en) 2018-08-31
AU2011207381A1 (en) 2012-07-26
CA2786149A1 (en) 2011-07-28
KR20190019220A (ko) 2019-02-26
BR112012018022A2 (pt) 2017-01-10
CA2786149C (en) 2019-11-12
KR20130004568A (ko) 2013-01-11
PT2525824T (pt) 2017-07-13
CN103154020B (zh) 2017-03-15
WO2011091305A3 (en) 2013-02-21
AU2011207381B2 (en) 2016-06-09
US8618254B2 (en) 2013-12-31
CN103154020A (zh) 2013-06-12
US9266947B2 (en) 2016-02-23
ES2632345T3 (es) 2017-09-12
EP3241840B1 (en) 2022-07-27
KR20200100866A (ko) 2020-08-26
EP2525824B1 (en) 2017-04-26
KR101951410B1 (ko) 2019-02-26
RU2556822C2 (ru) 2015-07-20
ZA201204866B (en) 2014-01-29
US20140065143A1 (en) 2014-03-06

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