PT3233825T - Derivados de diarilmetilideno-piperidina e sua utilização como agonistas do recetor opioide delta - Google Patents

Derivados de diarilmetilideno-piperidina e sua utilização como agonistas do recetor opioide delta

Info

Publication number
PT3233825T
PT3233825T PT158704650T PT15870465T PT3233825T PT 3233825 T PT3233825 T PT 3233825T PT 158704650 T PT158704650 T PT 158704650T PT 15870465 T PT15870465 T PT 15870465T PT 3233825 T PT3233825 T PT 3233825T
Authority
PT
Portugal
Prior art keywords
receptor agonists
opioid receptor
piperidine derivatives
delta opioid
diarylmethylidene piperidine
Prior art date
Application number
PT158704650T
Other languages
English (en)
Original Assignee
Pharmnovo Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmnovo Ab filed Critical Pharmnovo Ab
Publication of PT3233825T publication Critical patent/PT3233825T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
PT158704650T 2014-12-19 2015-12-17 Derivados de diarilmetilideno-piperidina e sua utilização como agonistas do recetor opioide delta PT3233825T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE1451616 2014-12-19

Publications (1)

Publication Number Publication Date
PT3233825T true PT3233825T (pt) 2020-07-15

Family

ID=56127081

Family Applications (1)

Application Number Title Priority Date Filing Date
PT158704650T PT3233825T (pt) 2014-12-19 2015-12-17 Derivados de diarilmetilideno-piperidina e sua utilização como agonistas do recetor opioide delta

Country Status (16)

Country Link
US (1) US10118921B2 (pt)
EP (1) EP3233825B1 (pt)
JP (1) JP6691135B2 (pt)
CN (1) CN107531670B (pt)
AU (1) AU2015363757B2 (pt)
CA (1) CA2970256C (pt)
DK (1) DK3233825T3 (pt)
ES (1) ES2808667T3 (pt)
HR (1) HRP20201050T1 (pt)
HU (1) HUE050241T2 (pt)
LT (1) LT3233825T (pt)
PL (1) PL3233825T3 (pt)
PT (1) PT3233825T (pt)
RS (1) RS60744B1 (pt)
SI (1) SI3233825T1 (pt)
WO (1) WO2016099393A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2021309364A1 (en) 2020-07-17 2023-02-16 Pharmnovo Ab Polymorphs of a hydrochloride salt of PN6047

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0101771D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101768D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0103313D0 (sv) * 2001-10-03 2001-10-03 Astrazeneca Ab Novel compounds
SE0300987D0 (sv) 2003-04-03 2003-04-03 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0301445D0 (sv) 2003-05-16 2003-05-16 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof

Also Published As

Publication number Publication date
ES2808667T3 (es) 2021-03-01
JP6691135B2 (ja) 2020-04-28
CA2970256C (en) 2022-03-29
CN107531670B (zh) 2020-12-15
AU2015363757B2 (en) 2019-11-14
DK3233825T3 (da) 2020-06-29
US20170327491A1 (en) 2017-11-16
US10118921B2 (en) 2018-11-06
PL3233825T3 (pl) 2020-11-02
EP3233825A4 (en) 2018-08-15
LT3233825T (lt) 2020-08-10
HRP20201050T1 (hr) 2020-10-30
RS60744B1 (sr) 2020-10-30
EP3233825A1 (en) 2017-10-25
HUE050241T2 (hu) 2020-11-30
SI3233825T1 (sl) 2020-10-30
CN107531670A (zh) 2018-01-02
CA2970256A1 (en) 2016-06-23
JP2018501314A (ja) 2018-01-18
EP3233825B1 (en) 2020-04-29
WO2016099393A1 (en) 2016-06-23
AU2015363757A1 (en) 2017-08-03

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