PT3204357T - Retinoides sintéticos fluorescentes - Google Patents

Retinoides sintéticos fluorescentes

Info

Publication number
PT3204357T
PT3204357T PT157985391T PT15798539T PT3204357T PT 3204357 T PT3204357 T PT 3204357T PT 157985391 T PT157985391 T PT 157985391T PT 15798539 T PT15798539 T PT 15798539T PT 3204357 T PT3204357 T PT 3204357T
Authority
PT
Portugal
Prior art keywords
synthetic retinoids
fluorescent synthetic
fluorescent
retinoids
synthetic
Prior art date
Application number
PT157985391T
Other languages
English (en)
Portuguese (pt)
Original Assignee
High Force Res Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB201417957A external-priority patent/GB201417957D0/en
Priority claimed from GB201419496A external-priority patent/GB201419496D0/en
Application filed by High Force Res Limited filed Critical High Force Res Limited
Publication of PT3204357T publication Critical patent/PT3204357T/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
    • C07D215/06—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms having only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to the ring nitrogen atom
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    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
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    • C09K11/00—Luminescent materials, e.g. electroluminescent or chemiluminescent
    • C09K11/06—Luminescent materials, e.g. electroluminescent or chemiluminescent containing organic luminescent materials
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • C12N5/0695—Stem cells; Progenitor cells; Precursor cells
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    • G01—MEASURING; TESTING
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    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N21/643—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" non-biological material
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
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  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
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  • Dermatology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Toxicology (AREA)
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  • Tropical Medicine & Parasitology (AREA)
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PT157985391T 2014-10-10 2015-10-09 Retinoides sintéticos fluorescentes PT3204357T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB201417957A GB201417957D0 (en) 2014-10-10 2014-10-10 Fluorescent synthetic retinoids
GB201419496A GB201419496D0 (en) 2014-10-31 2014-10-31 Fluorescent synthetic retinoids

Publications (1)

Publication Number Publication Date
PT3204357T true PT3204357T (pt) 2022-03-31

Family

ID=54697607

Family Applications (1)

Application Number Title Priority Date Filing Date
PT157985391T PT3204357T (pt) 2014-10-10 2015-10-09 Retinoides sintéticos fluorescentes

Country Status (12)

Country Link
US (1) US10759762B2 (Direct)
EP (1) EP3204357B1 (Direct)
JP (1) JP7178781B2 (Direct)
CN (1) CN107250112B (Direct)
AU (2) AU2015329798C1 (Direct)
CA (1) CA2962150C (Direct)
DK (1) DK3204357T3 (Direct)
ES (1) ES2909874T3 (Direct)
PL (1) PL3204357T3 (Direct)
PT (1) PT3204357T (Direct)
SI (1) SI3204357T1 (Direct)
WO (1) WO2016055800A2 (Direct)

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CN107176945B (zh) 2016-03-11 2021-06-08 中国科学院上海有机化学研究所 一种视黄酸类化合物、其制备方法、中间体及应用
ES3066492T3 (en) 2016-08-09 2026-05-13 Univ Of Durham Synthetic retinoids (in cell modulation)
GB201910239D0 (en) * 2019-07-17 2019-08-28 Lightox Ltd Fluorescent systems for biological imaging and uses thereof
JP7657223B2 (ja) 2019-12-19 2025-04-04 オルファゲン ファーマシューティカルズ，インク． 炎症性疾患および男性避妊用ｒａｒアルファ化合物
CN112479998B (zh) * 2020-11-16 2022-03-15 广州中医药大学(广州中医药研究院) 一种二氢喹啉类荧光探针及其制备方法与应用

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ES2909874T3 (es) 2022-05-10
US20170217893A1 (en) 2017-08-03
EP3204357A2 (en) 2017-08-16
JP7178781B2 (ja) 2022-11-28
CA2962150C (en) 2023-07-04
DK3204357T3 (da) 2022-04-04
AU2015329798C1 (en) 2019-10-24
SI3204357T1 (sl) 2022-05-31
WO2016055800A3 (en) 2016-06-16
AU2019203709A1 (en) 2019-06-20
AU2019203709B2 (en) 2020-10-22
CN107250112B (zh) 2021-04-23
JP2017537140A (ja) 2017-12-14
US10759762B2 (en) 2020-09-01
PL3204357T3 (pl) 2022-04-25
CN107250112A (zh) 2017-10-13
AU2015329798B2 (en) 2019-07-11
WO2016055800A2 (en) 2016-04-14
CA2962150A1 (en) 2016-04-14
AU2015329798A1 (en) 2017-05-11
EP3204357B1 (en) 2022-01-19

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