PT3203999T - Compostos aromáticos substituídos e composições farmacêuticas para a prevenção e tratamento da osteoporose - Google Patents

Compostos aromáticos substituídos e composições farmacêuticas para a prevenção e tratamento da osteoporose

Info

Publication number
PT3203999T
PT3203999T PT158496752T PT15849675T PT3203999T PT 3203999 T PT3203999 T PT 3203999T PT 158496752 T PT158496752 T PT 158496752T PT 15849675 T PT15849675 T PT 15849675T PT 3203999 T PT3203999 T PT 3203999T
Authority
PT
Portugal
Prior art keywords
osteoporosis
prevention
treatment
pharmaceutical compositions
aromatic compounds
Prior art date
Application number
PT158496752T
Other languages
English (en)
Original Assignee
Liminal Biosciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liminal Biosciences Ltd filed Critical Liminal Biosciences Ltd
Publication of PT3203999T publication Critical patent/PT3203999T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/32Phenylacetic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/42Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/52Unsaturated compounds containing hydroxy or O-metal groups a hydroxy or O-metal group being bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT158496752T 2014-10-10 2015-10-08 Compostos aromáticos substituídos e composições farmacêuticas para a prevenção e tratamento da osteoporose PT3203999T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462062597P 2014-10-10 2014-10-10

Publications (1)

Publication Number Publication Date
PT3203999T true PT3203999T (pt) 2020-04-23

Family

ID=55652429

Family Applications (1)

Application Number Title Priority Date Filing Date
PT158496752T PT3203999T (pt) 2014-10-10 2015-10-08 Compostos aromáticos substituídos e composições farmacêuticas para a prevenção e tratamento da osteoporose

Country Status (23)

Country Link
US (2) US20180228750A1 (pt)
EP (1) EP3203999B1 (pt)
JP (1) JP6700639B2 (pt)
KR (1) KR20170066476A (pt)
CN (1) CN106999456B (pt)
AR (1) AR102246A1 (pt)
AU (1) AU2015330645B2 (pt)
BR (1) BR112017007426A2 (pt)
CA (1) CA2963354A1 (pt)
DK (1) DK3203999T3 (pt)
ES (1) ES2785317T3 (pt)
IL (1) IL251404B (pt)
MX (1) MX2017004733A (pt)
MY (1) MY194308A (pt)
PH (1) PH12017500638A1 (pt)
PL (1) PL3203999T3 (pt)
PT (1) PT3203999T (pt)
RU (1) RU2709205C2 (pt)
SG (1) SG11201702868VA (pt)
TW (1) TWI699200B (pt)
UY (1) UY36356A (pt)
WO (1) WO2016054728A1 (pt)
ZA (1) ZA201702639B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20170072352A (ko) * 2014-11-12 2017-06-26 프로메틱 파마 에스엠티 리미티드 조직 자가-회복 및 재생을 위한 치환된 방향족 화합물 및 약제학적 조성물
SG10202103552XA (en) 2015-03-09 2021-05-28 Intekrin Therapeutics Inc Methods for the treatment of nonalcoholic fatty liver disease and/or lipodystrophy
US20190167660A1 (en) * 2016-08-18 2019-06-06 Intekrin Therapeutics, Inc. PPAR-gamma AGONIST FOR TREATMENT OF BONE DISORDERS
AU2018249822A1 (en) 2017-04-03 2019-10-31 Coherus Biosciences Inc. PPArgamma agonist for treatment of progressive supranuclear palsy
MX2023004137A (es) * 2020-10-06 2023-06-22 Pharmaceutique Ingenew Inc Compuestos aromaticos sustituidos y composiciones farmaceuticas de los mismos.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200720256A (en) * 2005-05-13 2007-06-01 Synta Pharmaceuticals Corp IL-12 modulatory compounds
AU2010244938A1 (en) * 2009-05-04 2011-11-17 Prometic Pharma Smt Limited Salts of 3-pentylphenylacetic acid and pharmaceutical uses thereof
PL2427416T3 (pl) * 2009-05-04 2016-09-30 Podstawione związki aromatyczne i ich zastosowania farmaceutyczne
AU2011320057B2 (en) * 2010-10-27 2016-02-25 Liminal Biosciences Limited Phenylketone carboxylate compounds and pharmaceutical uses thereof
NZ610851A (en) * 2010-10-27 2015-05-29 Prometic Biosciences Inc Compounds and compositions for the treatment of cancer
TWI742541B (zh) * 2013-03-15 2021-10-11 英商邊緣生物科技有限公司 用於治療肺纖維化、肝纖維化、皮膚纖維化及心臟纖維化之經取代之芳族化合物
TWI689490B (zh) * 2013-03-15 2020-04-01 英商邊緣生物科技有限公司 用於治療纖維化之經取代之芳族化合物及相關方法

Also Published As

Publication number Publication date
MX2017004733A (es) 2017-07-17
EP3203999B1 (en) 2020-01-08
CN106999456B (zh) 2020-07-10
SG11201702868VA (en) 2017-05-30
AR102246A1 (es) 2017-02-15
BR112017007426A2 (pt) 2018-01-16
IL251404A0 (en) 2017-05-29
US20180228750A1 (en) 2018-08-16
IL251404B (en) 2020-11-30
EP3203999A4 (en) 2018-06-27
ES2785317T3 (es) 2020-10-06
PL3203999T3 (pl) 2020-07-27
AU2015330645B2 (en) 2020-03-12
DK3203999T3 (da) 2020-03-30
MY194308A (en) 2022-11-27
US20200237693A1 (en) 2020-07-30
EP3203999A1 (en) 2017-08-16
AU2015330645A1 (en) 2017-05-04
RU2017116178A (ru) 2018-11-19
US11185521B2 (en) 2021-11-30
ZA201702639B (en) 2018-06-27
JP2017530180A (ja) 2017-10-12
CN106999456A (zh) 2017-08-01
TWI699200B (zh) 2020-07-21
WO2016054728A1 (en) 2016-04-14
KR20170066476A (ko) 2017-06-14
JP6700639B2 (ja) 2020-05-27
PH12017500638A1 (en) 2017-09-25
RU2017116178A3 (pt) 2019-05-16
UY36356A (es) 2016-06-01
RU2709205C2 (ru) 2019-12-17
CA2963354A1 (en) 2016-04-14
TW201618762A (zh) 2016-06-01

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