PT3203999T - Compostos aromáticos substituídos e composições farmacêuticas para a prevenção e tratamento da osteoporose - Google Patents

Compostos aromáticos substituídos e composições farmacêuticas para a prevenção e tratamento da osteoporose

Info

Publication number
PT3203999T
PT3203999T PT158496752T PT15849675T PT3203999T PT 3203999 T PT3203999 T PT 3203999T PT 158496752 T PT158496752 T PT 158496752T PT 15849675 T PT15849675 T PT 15849675T PT 3203999 T PT3203999 T PT 3203999T
Authority
PT
Portugal
Prior art keywords
osteoporosis
prevention
treatment
pharmaceutical compositions
aromatic compounds
Prior art date
Application number
PT158496752T
Other languages
English (en)
Original Assignee
Liminal Biosciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liminal Biosciences Ltd filed Critical Liminal Biosciences Ltd
Publication of PT3203999T publication Critical patent/PT3203999T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/32Phenylacetic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/42Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/52Unsaturated compounds containing hydroxy or O-metal groups a hydroxy or O-metal group being bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT158496752T 2014-10-10 2015-10-08 Compostos aromáticos substituídos e composições farmacêuticas para a prevenção e tratamento da osteoporose PT3203999T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462062597P 2014-10-10 2014-10-10

Publications (1)

Publication Number Publication Date
PT3203999T true PT3203999T (pt) 2020-04-23

Family

ID=55652429

Family Applications (1)

Application Number Title Priority Date Filing Date
PT158496752T PT3203999T (pt) 2014-10-10 2015-10-08 Compostos aromáticos substituídos e composições farmacêuticas para a prevenção e tratamento da osteoporose

Country Status (23)

Country Link
US (2) US20180228750A1 (pt)
EP (1) EP3203999B1 (pt)
JP (1) JP6700639B2 (pt)
KR (1) KR20170066476A (pt)
CN (1) CN106999456B (pt)
AR (1) AR102246A1 (pt)
AU (1) AU2015330645B2 (pt)
BR (1) BR112017007426A2 (pt)
CA (1) CA2963354A1 (pt)
DK (1) DK3203999T3 (pt)
ES (1) ES2785317T3 (pt)
IL (1) IL251404B (pt)
MX (1) MX2017004733A (pt)
MY (1) MY194308A (pt)
PH (1) PH12017500638A1 (pt)
PL (1) PL3203999T3 (pt)
PT (1) PT3203999T (pt)
RU (1) RU2709205C2 (pt)
SG (1) SG11201702868VA (pt)
TW (1) TWI699200B (pt)
UY (1) UY36356A (pt)
WO (1) WO2016054728A1 (pt)
ZA (1) ZA201702639B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3217968A4 (en) 2014-11-12 2018-06-20 Prometic Pharma Smt Limited Substituted aromatic compounds and pharmaceutical compositions for tissue self-repair and regeneration
WO2016144862A1 (en) 2015-03-09 2016-09-15 Intekrin Therapeutics, Inc. Methods for the treatment of nonalcoholic fatty liver disease and/or lipodystrophy
AU2017313842A1 (en) * 2016-08-18 2019-03-07 Intekrin Therapeutics, Inc. PPARgamma AGONIST FOR TREATMENT OF BONE DISORDERS
CA3058806A1 (en) 2017-04-03 2018-10-11 Coherus Biosciences Inc. Ppar.gamma. agonist for treatment of progressive supranuclear palsy
WO2022073115A1 (en) * 2020-10-06 2022-04-14 Biopharmaceutiques Ingenew Inc. Substituted aromatic compounds and pharmaceutical compositions thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7863270B2 (en) * 2005-05-13 2011-01-04 Synta Pharmaceuticals Corp. IL-12 modulatory compounds
MY156780A (en) * 2009-05-04 2016-03-31 Prometic Biosciences Inc Substituted aromatic compounds and pharmaceutical uses thereof
JP5844251B2 (ja) * 2009-05-04 2016-01-13 プロメティック・バイオサイエンシーズ・インコーポレイテッドProMetic BioSciences Inc. 3−ペンチルフェニル酢酸の塩およびその薬学的使用
US9475750B2 (en) * 2010-10-27 2016-10-25 Prometic Biosciences Inc. Phenylketone carboxylate compounds and pharmaceutical uses thereof
CN103347509B (zh) * 2010-10-27 2016-06-08 普罗米蒂克生物科学公司 用于治疗癌症的化合物和组合物
TWI689489B (zh) * 2013-03-15 2020-04-01 英商邊緣生物科技有限公司 用於治療肺纖維化、肝纖維化、皮膚纖維化及心臟纖維化之經取代之芳族化合物
TWI689490B (zh) * 2013-03-15 2020-04-01 英商邊緣生物科技有限公司 用於治療纖維化之經取代之芳族化合物及相關方法

Also Published As

Publication number Publication date
MX2017004733A (es) 2017-07-17
EP3203999A1 (en) 2017-08-16
IL251404A0 (en) 2017-05-29
EP3203999A4 (en) 2018-06-27
US20180228750A1 (en) 2018-08-16
KR20170066476A (ko) 2017-06-14
US11185521B2 (en) 2021-11-30
UY36356A (es) 2016-06-01
BR112017007426A2 (pt) 2018-01-16
CN106999456A (zh) 2017-08-01
ES2785317T3 (es) 2020-10-06
RU2017116178A (ru) 2018-11-19
AR102246A1 (es) 2017-02-15
DK3203999T3 (da) 2020-03-30
TW201618762A (zh) 2016-06-01
PH12017500638A1 (en) 2017-09-25
ZA201702639B (en) 2018-06-27
CA2963354A1 (en) 2016-04-14
AU2015330645A1 (en) 2017-05-04
IL251404B (en) 2020-11-30
US20200237693A1 (en) 2020-07-30
TWI699200B (zh) 2020-07-21
SG11201702868VA (en) 2017-05-30
CN106999456B (zh) 2020-07-10
JP6700639B2 (ja) 2020-05-27
PL3203999T3 (pl) 2020-07-27
EP3203999B1 (en) 2020-01-08
AU2015330645B2 (en) 2020-03-12
RU2709205C2 (ru) 2019-12-17
JP2017530180A (ja) 2017-10-12
RU2017116178A3 (pt) 2019-05-16
MY194308A (en) 2022-11-27
WO2016054728A1 (en) 2016-04-14

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