PT3087076T - Derivados de imidazopirazinona - Google Patents
Derivados de imidazopirazinonaInfo
- Publication number
- PT3087076T PT3087076T PT148085061T PT14808506T PT3087076T PT 3087076 T PT3087076 T PT 3087076T PT 148085061 T PT148085061 T PT 148085061T PT 14808506 T PT14808506 T PT 14808506T PT 3087076 T PT3087076 T PT 3087076T
- Authority
- PT
- Portugal
- Prior art keywords
- imidazopyrazinone
- derivatives
- imidazopyrazinone derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/527—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim spiro-condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Lubricants (AREA)
- Developing Agents For Electrophotography (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13006052 | 2013-12-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3087076T true PT3087076T (pt) | 2018-01-03 |
Family
ID=49916790
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT148085061T PT3087076T (pt) | 2013-12-23 | 2014-12-03 | Derivados de imidazopirazinona |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US9718826B2 (pt) |
| EP (1) | EP3087076B1 (pt) |
| JP (1) | JP6446461B2 (pt) |
| KR (1) | KR20160101188A (pt) |
| CN (1) | CN105829317B (pt) |
| AU (1) | AU2014372896B2 (pt) |
| CA (1) | CA2934663A1 (pt) |
| DK (1) | DK3087076T3 (pt) |
| ES (1) | ES2654403T3 (pt) |
| HR (1) | HRP20171783T1 (pt) |
| HU (1) | HUE037606T2 (pt) |
| IL (1) | IL246406A0 (pt) |
| LT (1) | LT3087076T (pt) |
| MX (1) | MX364859B (pt) |
| NO (1) | NO3087076T3 (pt) |
| PL (1) | PL3087076T3 (pt) |
| PT (1) | PT3087076T (pt) |
| RS (1) | RS56746B1 (pt) |
| RU (1) | RU2672885C2 (pt) |
| SG (1) | SG11201605189YA (pt) |
| SI (1) | SI3087076T1 (pt) |
| TW (1) | TWI637956B (pt) |
| WO (1) | WO2015096884A1 (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10722484B2 (en) | 2016-03-09 | 2020-07-28 | K-Gen, Inc. | Methods of cancer treatment |
| TWI794171B (zh) | 2016-05-11 | 2023-03-01 | 美商滬亞生物國際有限公司 | Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療 |
| TWI808055B (zh) | 2016-05-11 | 2023-07-11 | 美商滬亞生物國際有限公司 | Hdac 抑制劑與 pd-1 抑制劑之組合治療 |
| TW201822637A (zh) | 2016-11-07 | 2018-07-01 | 德商拜耳廠股份有限公司 | 用於控制動物害蟲的經取代磺醯胺類 |
| CN108403697A (zh) * | 2018-05-02 | 2018-08-17 | 吉林大学 | 吡嗪酮类小分子抑制剂在制备抗肿瘤药物中的应用 |
| WO2020049017A1 (en) * | 2018-09-07 | 2020-03-12 | Merck Patent Gmbh | 5-morpholin-4-yl-pyrazolo[4,3-b]pyridine derivatives |
| JP7433403B1 (ja) | 2022-12-06 | 2024-02-19 | 本田技研工業株式会社 | 内燃機関及び鞍乗型車両 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005089352A (ja) * | 2003-09-16 | 2005-04-07 | Kissei Pharmaceut Co Ltd | 新規なイミダゾ［１，５−ａ］ピラジン誘導体、それを含有する医薬組成物およびそれらの用途 |
| CN101468988A (zh) * | 2007-12-26 | 2009-07-01 | 上海恒瑞医药有限公司 | 哌嗪类衍生物,其制备方法及其在医药上的应用 |
| WO2011089400A1 (en) | 2010-01-22 | 2011-07-28 | Centro Nacional De Investigaciones Oncológicas (Cnio) | Inhibitors of pi3 kinase |
| RS54997B1 (sr) * | 2012-03-28 | 2016-11-30 | Merck Patent Gmbh | Biciklični pirazinon derivati |
| HUE028325T2 (en) * | 2012-05-04 | 2016-12-28 | Merck Patent Gmbh | Pyrrolotriazines derivatives |
-
2014
- 2014-12-03 PL PL14808506T patent/PL3087076T3/pl unknown
- 2014-12-03 CA CA2934663A patent/CA2934663A1/en not_active Abandoned
- 2014-12-03 DK DK14808506.1T patent/DK3087076T3/da active
- 2014-12-03 JP JP2016542145A patent/JP6446461B2/ja not_active Expired - Fee Related
- 2014-12-03 EP EP14808506.1A patent/EP3087076B1/en active Active
- 2014-12-03 RU RU2016130148A patent/RU2672885C2/ru active
- 2014-12-03 MX MX2016008042A patent/MX364859B/es active IP Right Grant
- 2014-12-03 US US15/107,211 patent/US9718826B2/en active Active
- 2014-12-03 WO PCT/EP2014/003226 patent/WO2015096884A1/en active Application Filing
- 2014-12-03 KR KR1020167020018A patent/KR20160101188A/ko not_active Application Discontinuation
- 2014-12-03 NO NO14808506A patent/NO3087076T3/no unknown
- 2014-12-03 LT LTEP14808506.1T patent/LT3087076T/lt unknown
- 2014-12-03 CN CN201480070682.1A patent/CN105829317B/zh not_active Expired - Fee Related
- 2014-12-03 SI SI201430528T patent/SI3087076T1/en unknown
- 2014-12-03 PT PT148085061T patent/PT3087076T/pt unknown
- 2014-12-03 AU AU2014372896A patent/AU2014372896B2/en not_active Ceased
- 2014-12-03 HU HUE14808506A patent/HUE037606T2/hu unknown
- 2014-12-03 ES ES14808506.1T patent/ES2654403T3/es active Active
- 2014-12-03 RS RS20171341A patent/RS56746B1/sr unknown
- 2014-12-03 SG SG11201605189YA patent/SG11201605189YA/en unknown
- 2014-12-22 TW TW103144858A patent/TWI637956B/zh not_active IP Right Cessation
-
2016
- 2016-06-22 IL IL246406A patent/IL246406A0/en active IP Right Grant
-
2017
- 2017-11-16 HR HRP20171783TT patent/HRP20171783T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2017500353A (ja) | 2017-01-05 |
| US9718826B2 (en) | 2017-08-01 |
| RU2672885C2 (ru) | 2018-11-20 |
| ES2654403T3 (es) | 2018-02-13 |
| TW201605862A (zh) | 2016-02-16 |
| LT3087076T (lt) | 2017-12-27 |
| DK3087076T3 (da) | 2017-11-13 |
| EP3087076B1 (en) | 2017-09-27 |
| KR20160101188A (ko) | 2016-08-24 |
| TWI637956B (zh) | 2018-10-11 |
| CN105829317B (zh) | 2019-03-29 |
| RS56746B1 (sr) | 2018-03-30 |
| NO3087076T3 (pt) | 2018-02-24 |
| CA2934663A1 (en) | 2015-07-02 |
| MX2016008042A (es) | 2016-09-16 |
| RU2016130148A (ru) | 2018-01-30 |
| HUE037606T2 (hu) | 2018-09-28 |
| EP3087076A1 (en) | 2016-11-02 |
| PL3087076T3 (pl) | 2018-01-31 |
| RU2016130148A3 (pt) | 2018-07-25 |
| AU2014372896B2 (en) | 2018-08-16 |
| AU2014372896A1 (en) | 2016-08-04 |
| SG11201605189YA (en) | 2016-07-28 |
| US20170002010A1 (en) | 2017-01-05 |
| JP6446461B2 (ja) | 2018-12-26 |
| SI3087076T1 (en) | 2018-01-31 |
| CN105829317A (zh) | 2016-08-03 |
| HRP20171783T1 (hr) | 2017-12-29 |
| MX364859B (es) | 2019-05-09 |
| IL246406A0 (en) | 2016-08-31 |
| WO2015096884A1 (en) | 2015-07-02 |
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