PT3010879T - Derivados de hiperforina e a sua utilização na doença de alzheimer - Google Patents

Derivados de hiperforina e a sua utilização na doença de alzheimer

Info

Publication number
PT3010879T
PT3010879T PT147358725T PT14735872T PT3010879T PT 3010879 T PT3010879 T PT 3010879T PT 147358725 T PT147358725 T PT 147358725T PT 14735872 T PT14735872 T PT 14735872T PT 3010879 T PT3010879 T PT 3010879T
Authority
PT
Portugal
Prior art keywords
alzheimer
disease
hyperforin derivatives
hyperforin
derivatives
Prior art date
Application number
PT147358725T
Other languages
English (en)
Inventor
Riva Antonella
Fontana Gabriele
Morazzoni Paolo
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Publication of PT3010879T publication Critical patent/PT3010879T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/757Unsaturated compounds containing a keto groups being part of a ring containing —CHO groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/36Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/46Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing nine carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT147358725T 2013-06-19 2014-06-17 Derivados de hiperforina e a sua utilização na doença de alzheimer PT3010879T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT001012A ITMI20131012A1 (it) 2013-06-19 2013-06-19 Derivati dell'iperforina e loro uso nella malattia di alzheimer

Publications (1)

Publication Number Publication Date
PT3010879T true PT3010879T (pt) 2017-11-10

Family

ID=49035703

Family Applications (1)

Application Number Title Priority Date Filing Date
PT147358725T PT3010879T (pt) 2013-06-19 2014-06-17 Derivados de hiperforina e a sua utilização na doença de alzheimer

Country Status (20)

Country Link
US (1) US9556099B2 (pt)
EP (1) EP3010879B1 (pt)
JP (1) JP2016522233A (pt)
KR (1) KR20160021115A (pt)
CN (1) CN105283434A (pt)
AU (1) AU2014283361B2 (pt)
BR (1) BR112015030598A2 (pt)
CA (1) CA2915424A1 (pt)
DK (1) DK3010879T3 (pt)
ES (1) ES2645471T3 (pt)
HK (1) HK1220685A1 (pt)
IL (1) IL243094A0 (pt)
IT (1) ITMI20131012A1 (pt)
MX (1) MX2015017276A (pt)
PL (1) PL3010879T3 (pt)
PT (1) PT3010879T (pt)
RU (1) RU2015153437A (pt)
SG (1) SG11201510226YA (pt)
SI (1) SI3010879T1 (pt)
WO (1) WO2014202597A1 (pt)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6444662B1 (en) 1998-02-13 2002-09-03 Willmar Schwabe Gmbh & Co. Stable hyperforin salts, method for producing same and their use in the treatment of alzheimer's disease
IT1301679B1 (it) 1998-06-10 2000-07-07 Indena Spa Derivati dell'iperforina, loro uso e formulazioni che licontengono.
ITMI20020872A1 (it) * 2002-04-23 2003-10-23 Indena Spa Derivati dell'iperforina loro uso e formulazioni che li contengono

Also Published As

Publication number Publication date
SG11201510226YA (en) 2016-01-28
DK3010879T3 (en) 2017-09-04
ES2645471T3 (es) 2017-12-05
AU2014283361B2 (en) 2017-10-12
HK1220685A1 (zh) 2017-05-12
BR112015030598A2 (pt) 2017-07-25
MX2015017276A (es) 2016-04-06
AU2014283361A1 (en) 2016-01-07
EP3010879B1 (en) 2017-08-02
EP3010879A1 (en) 2016-04-27
CN105283434A (zh) 2016-01-27
KR20160021115A (ko) 2016-02-24
CA2915424A1 (en) 2014-12-24
ITMI20131012A1 (it) 2014-12-20
SI3010879T1 (sl) 2017-10-30
US9556099B2 (en) 2017-01-31
PL3010879T3 (pl) 2018-01-31
US20160115111A1 (en) 2016-04-28
WO2014202597A1 (en) 2014-12-24
JP2016522233A (ja) 2016-07-28
IL243094A0 (en) 2016-02-01
RU2015153437A (ru) 2017-06-20

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