PT2953975T - Agente de imunoimagiologia para utilização com uma terapia de conjugado anticorpo-fármaco - Google Patents

Agente de imunoimagiologia para utilização com uma terapia de conjugado anticorpo-fármaco

Info

Publication number
PT2953975T
PT2953975T PT147054555T PT14705455T PT2953975T PT 2953975 T PT2953975 T PT 2953975T PT 147054555 T PT147054555 T PT 147054555T PT 14705455 T PT14705455 T PT 14705455T PT 2953975 T PT2953975 T PT 2953975T
Authority
PT
Portugal
Prior art keywords
antibody
drug conjugate
imaging agent
conjugate therapy
immuno
Prior art date
Application number
PT147054555T
Other languages
English (en)
Portuguese (pt)
Inventor
Kruip Jochen
S Gambhir Sanjiv
K Sarkar Susanta
Gebauer Mathias
Lange Christian
Focken Ingo
Kimura Richard
Natarajan Arutselvan
Ilovich Ohad
Original Assignee
Sanofi Sa
Univ Leland Stanford Junior
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa, Univ Leland Stanford Junior filed Critical Sanofi Sa
Publication of PT2953975T publication Critical patent/PT2953975T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1027—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3076—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
    • C07K16/3092—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties against tumour-associated mucins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/624—Disulfide-stabilized antibody (dsFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/626—Diabody or triabody

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
PT147054555T 2013-02-05 2014-02-05 Agente de imunoimagiologia para utilização com uma terapia de conjugado anticorpo-fármaco PT2953975T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361761188P 2013-02-05 2013-02-05
EP14305081 2014-01-21

Publications (1)

Publication Number Publication Date
PT2953975T true PT2953975T (pt) 2017-10-30

Family

ID=50031281

Family Applications (1)

Application Number Title Priority Date Filing Date
PT147054555T PT2953975T (pt) 2013-02-05 2014-02-05 Agente de imunoimagiologia para utilização com uma terapia de conjugado anticorpo-fármaco

Country Status (16)

Country Link
EP (1) EP2953975B1 (fr)
KR (1) KR20150113196A (fr)
CN (1) CN105143272A (fr)
AU (1) AU2014214997A1 (fr)
CA (1) CA2900255A1 (fr)
DK (1) DK2953975T3 (fr)
ES (1) ES2644668T3 (fr)
HU (1) HUE037456T2 (fr)
LT (1) LT2953975T (fr)
MX (1) MX2015010144A (fr)
PL (1) PL2953975T3 (fr)
PT (1) PT2953975T (fr)
RU (1) RU2015137856A (fr)
SG (1) SG11201506053VA (fr)
SI (1) SI2953975T1 (fr)
WO (1) WO2014124026A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117285631A (zh) * 2023-11-24 2023-12-26 原子高科股份有限公司 用于放射性免疫治疗的Lu-177标记MUC1抗体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001270609A1 (en) * 2000-06-30 2002-01-14 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw Heterodimeric fusion proteins
EA020130B9 (ru) * 2005-08-22 2014-10-30 Иммьюноджен, Инк. Специфичное к антигену са6 антитело, содержащий его цитотоксический конъюгат и способы применения конъюгата
GB0822001D0 (en) * 2008-12-02 2009-01-07 Glaxosmithkline Biolog Sa Vaccine
NZ598929A (en) * 2009-09-01 2014-05-30 Abbvie Inc Dual variable domain immunoglobulins and uses thereof
GB201005063D0 (en) * 2010-03-25 2010-05-12 Ucb Pharma Sa Biological products

Also Published As

Publication number Publication date
EP2953975A1 (fr) 2015-12-16
KR20150113196A (ko) 2015-10-07
CA2900255A1 (fr) 2014-08-14
DK2953975T3 (en) 2017-12-11
EP2953975B1 (fr) 2017-09-06
PL2953975T3 (pl) 2018-02-28
AU2014214997A1 (en) 2015-08-20
LT2953975T (lt) 2017-12-27
ES2644668T3 (es) 2017-11-29
RU2015137856A (ru) 2017-03-13
WO2014124026A1 (fr) 2014-08-14
MX2015010144A (es) 2016-05-31
CN105143272A (zh) 2015-12-09
SG11201506053VA (en) 2015-08-28
SI2953975T1 (en) 2018-02-28
HUE037456T2 (hu) 2018-08-28

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