PT2821085T - Interferência de arn para o tratamento de distúrbios de ganho de função - Google Patents
Interferência de arn para o tratamento de distúrbios de ganho de funçãoInfo
- Publication number
- PT2821085T PT2821085T PT141686022T PT14168602T PT2821085T PT 2821085 T PT2821085 T PT 2821085T PT 141686022 T PT141686022 T PT 141686022T PT 14168602 T PT14168602 T PT 14168602T PT 2821085 T PT2821085 T PT 2821085T
- Authority
- PT
- Portugal
- Prior art keywords
- gain
- treatment
- rna interference
- function disorders
- disorders
- Prior art date
Links
- 238000012228 RNA interference-mediated gene silencing Methods 0.000 title 1
- 230000009368 gene silencing by RNA Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50267803P | 2003-09-12 | 2003-09-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT2821085T true PT2821085T (pt) | 2020-07-28 |
Family
ID=34375272
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT141686022T PT2821085T (pt) | 2003-09-12 | 2004-09-13 | Interferência de arn para o tratamento de distúrbios de ganho de função |
Country Status (7)
Country | Link |
---|---|
US (1) | US7947658B2 (pt) |
EP (3) | EP2821085B1 (pt) |
CA (1) | CA2579638C (pt) |
DK (1) | DK2821085T3 (pt) |
ES (2) | ES2808561T3 (pt) |
PT (1) | PT2821085T (pt) |
WO (1) | WO2005027980A1 (pt) |
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EP2239328A3 (en) | 2005-08-18 | 2011-01-05 | Alnylam Pharmaceuticals Inc. | Methods and compositions for treating neurological disease |
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-
2004
- 2004-09-13 US US10/571,705 patent/US7947658B2/en active Active
- 2004-09-13 EP EP14168602.2A patent/EP2821085B1/en active Active
- 2004-09-13 EP EP04783980.8A patent/EP1670518B1/en active Active
- 2004-09-13 CA CA2579638A patent/CA2579638C/en active Active
- 2004-09-13 ES ES14168602T patent/ES2808561T3/es active Active
- 2004-09-13 DK DK14168602.2T patent/DK2821085T3/da active
- 2004-09-13 WO PCT/US2004/029968 patent/WO2005027980A1/en active Application Filing
- 2004-09-13 EP EP20171780.8A patent/EP3760234B1/en active Active
- 2004-09-13 ES ES04783980.8T patent/ES2485848T3/es active Active
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CA2579638A1 (en) | 2005-03-31 |
CA2579638C (en) | 2016-04-19 |
EP2821085B1 (en) | 2020-04-29 |
EP1670518A1 (en) | 2006-06-21 |
EP3760234B1 (en) | 2023-11-01 |
ES2485848T3 (es) | 2014-08-14 |
EP1670518B1 (en) | 2014-05-21 |
US7947658B2 (en) | 2011-05-24 |
EP2821085A3 (en) | 2015-04-22 |
DK2821085T3 (da) | 2020-08-03 |
WO2005027980A1 (en) | 2005-03-31 |
EP3760234A3 (en) | 2021-04-07 |
EP2821085A2 (en) | 2015-01-07 |
EP3760234A2 (en) | 2021-01-06 |
ES2808561T3 (es) | 2021-03-01 |
EP1670518A4 (en) | 2007-10-10 |
US20090118206A1 (en) | 2009-05-07 |
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