PT2744831T - Proteína de fusão de transferrina-tumstatina e métodos para a produzir e utilizar - Google Patents
Proteína de fusão de transferrina-tumstatina e métodos para a produzir e utilizarInfo
- Publication number
- PT2744831T PT2744831T PT128246162T PT12824616T PT2744831T PT 2744831 T PT2744831 T PT 2744831T PT 128246162 T PT128246162 T PT 128246162T PT 12824616 T PT12824616 T PT 12824616T PT 2744831 T PT2744831 T PT 2744831T
- Authority
- PT
- Portugal
- Prior art keywords
- transferrin
- producing
- methods
- same
- fusion protein
- Prior art date
Links
- 108020001507 fusion proteins Proteins 0.000 title 1
- 102000037865 fusion proteins Human genes 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/60—Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161524508P | 2011-08-17 | 2011-08-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2744831T true PT2744831T (pt) | 2018-03-05 |
Family
ID=47715692
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT128246162T PT2744831T (pt) | 2011-08-17 | 2012-08-15 | Proteína de fusão de transferrina-tumstatina e métodos para a produzir e utilizar |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9290562B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2744831B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6073888B2 (cg-RX-API-DMAC7.html) |
| CN (2) | CN103998470A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2012296588B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112014008680A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2849015C (cg-RX-API-DMAC7.html) |
| DK (1) | DK2744831T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2659161T3 (cg-RX-API-DMAC7.html) |
| NO (1) | NO2820418T3 (cg-RX-API-DMAC7.html) |
| PL (1) | PL2744831T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT2744831T (cg-RX-API-DMAC7.html) |
| SI (1) | SI2744831T1 (cg-RX-API-DMAC7.html) |
| TR (1) | TR201802686T4 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2013025846A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014180288A1 (zh) * | 2013-05-06 | 2014-11-13 | 中国药科大学 | 具有抑制肿瘤微环境血管再生和激活适应性免疫应答双功能的融合蛋白及其基因和应用 |
| WO2014203182A1 (en) * | 2013-06-20 | 2014-12-24 | Novartis Ag | Use of a vegf antagonist in treating choroidal neovascularisation |
| US11058750B2 (en) | 2015-12-03 | 2021-07-13 | Mor Research Applications Ltd. | Compositions and methods for treatment of ocular diseases |
| KR101818151B1 (ko) | 2016-03-25 | 2018-01-16 | 한국과학기술원 | 트렌스페린을 포함하는 허혈성망막병증 예방 및 치료용 조성물 |
| CN109053899B (zh) * | 2017-12-22 | 2021-11-16 | 湖南远泰生物技术有限公司 | 一种含人转铁蛋白抗原表位序列的嵌合体抗原受体 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5672683A (en) | 1989-09-07 | 1997-09-30 | Alkermes, Inc. | Transferrin neuropharmaceutical agent fusion protein |
| US20050192242A1 (en) | 1995-10-11 | 2005-09-01 | Neal Zane C. | Therapeutic fusion protein transgenes |
| CA2331332A1 (en) * | 1998-06-17 | 1999-12-23 | Raghuram Kalluri | Anti-angiogenic proteins and methods of use thereof |
| JP2003517847A (ja) | 1999-12-23 | 2003-06-03 | ヒューマン ジノーム サイエンシーズ， インコーポレイテッド | トランスフェリンポリヌクレオチド、ポリペプチド、および抗体 |
| WO2003020746A1 (en) | 2001-08-30 | 2003-03-13 | Biorexis Pharmaceutical Corporation | Modified transferrin fusion proteins |
| US8129504B2 (en) * | 2001-08-30 | 2012-03-06 | Biorexis Technology, Inc. | Oral delivery of modified transferrin fusion proteins |
| EP2261250B1 (en) | 2001-12-21 | 2015-07-01 | Human Genome Sciences, Inc. | GCSF-Albumin fusion proteins |
| NZ534310A (en) * | 2002-02-07 | 2008-03-28 | Novozymes Delta Ltd | Albumin-fused anti-angiogenesis peptides |
| EP1670428A4 (en) | 2003-10-10 | 2008-03-12 | Univ Southern California | HYBRID PROTEINS G-CSF-TRANSFERRIN |
| EP1722762A2 (en) * | 2004-03-02 | 2006-11-22 | Massachusetts Institute of Technology | Nanocell drug delivery system |
| WO2006044614A2 (en) | 2004-10-14 | 2006-04-27 | Sopherion Therapeutics, Inc. | Anti-angiogenic peptides and methods of use thereof |
| WO2006049983A2 (en) | 2004-10-27 | 2006-05-11 | Biorexis Pharmaceutical Corporation | Peptide yy modified transferrin fusion proteins |
| WO2006119128A2 (en) * | 2005-04-29 | 2006-11-09 | Research Development Foundation | Vascular targeting of ocular neovascularization |
| EP2468294A1 (en) | 2006-02-03 | 2012-06-27 | Crc For Asthma And Airways Ltd | A method of modulating cellular activity and agents for use therein |
| CN101070349B (zh) * | 2007-05-22 | 2010-10-13 | 山西康宝生物制品股份有限公司 | 具有选择性杀伤肿瘤新生血管内皮细胞作用的融合蛋白与应用 |
| CN101092452A (zh) * | 2007-05-23 | 2007-12-26 | 哈尔滨医科大学 | 肿瘤抑素抗血管生成小分子多肽、融合蛋白及两者制备方法 |
| WO2009086132A2 (en) * | 2007-12-20 | 2009-07-09 | University Of Southern California | Design of spacers to increase the expression of recombinant fusion proteins |
| JP6101638B2 (ja) | 2011-03-03 | 2017-03-22 | ザイムワークス，インコーポレイテッド | 多価ヘテロマルチマー足場設計及び構築物 |
-
2012
- 2012-08-15 ES ES12824616.2T patent/ES2659161T3/es active Active
- 2012-08-15 AU AU2012296588A patent/AU2012296588B2/en active Active
- 2012-08-15 JP JP2014526189A patent/JP6073888B2/ja active Active
- 2012-08-15 PT PT128246162T patent/PT2744831T/pt unknown
- 2012-08-15 WO PCT/US2012/051013 patent/WO2013025846A2/en not_active Ceased
- 2012-08-15 TR TR2018/02686T patent/TR201802686T4/tr unknown
- 2012-08-15 SI SI201231232T patent/SI2744831T1/en unknown
- 2012-08-15 CN CN201280051256.4A patent/CN103998470A/zh active Pending
- 2012-08-15 CA CA2849015A patent/CA2849015C/en active Active
- 2012-08-15 DK DK12824616.2T patent/DK2744831T3/en active
- 2012-08-15 BR BR112014008680A patent/BR112014008680A2/pt unknown
- 2012-08-15 EP EP12824616.2A patent/EP2744831B1/en active Active
- 2012-08-15 US US14/239,176 patent/US9290562B2/en active Active
- 2012-08-15 PL PL12824616T patent/PL2744831T3/pl unknown
- 2012-08-15 CN CN201910156923.9A patent/CN110105453A/zh active Pending
-
2013
- 2013-07-22 NO NO13745268A patent/NO2820418T3/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013025846A2 (en) | 2013-02-21 |
| TR201802686T4 (tr) | 2018-03-21 |
| JP2014526890A (ja) | 2014-10-09 |
| CA2849015C (en) | 2017-08-08 |
| NO2820418T3 (cg-RX-API-DMAC7.html) | 2018-05-05 |
| EP2744831A2 (en) | 2014-06-25 |
| PL2744831T3 (pl) | 2018-05-30 |
| JP6073888B2 (ja) | 2017-02-01 |
| SI2744831T1 (en) | 2018-04-30 |
| US9290562B2 (en) | 2016-03-22 |
| DK2744831T3 (en) | 2018-03-05 |
| US20140179612A1 (en) | 2014-06-26 |
| AU2012296588B2 (en) | 2017-07-27 |
| AU2012296588A1 (en) | 2014-04-03 |
| CA2849015A1 (en) | 2013-02-21 |
| CN103998470A (zh) | 2014-08-20 |
| EP2744831A4 (en) | 2015-03-11 |
| EP2744831B1 (en) | 2017-12-06 |
| BR112014008680A2 (pt) | 2017-06-13 |
| ES2659161T3 (es) | 2018-03-14 |
| CN110105453A (zh) | 2019-08-09 |
| WO2013025846A3 (en) | 2013-05-02 |
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