PT2307458T - Humanization of rabbit antibodies using a universal antibody framework - Google Patents
Humanization of rabbit antibodies using a universal antibody frameworkInfo
- Publication number
- PT2307458T PT2307458T PT97686950T PT09768695T PT2307458T PT 2307458 T PT2307458 T PT 2307458T PT 97686950 T PT97686950 T PT 97686950T PT 09768695 T PT09768695 T PT 09768695T PT 2307458 T PT2307458 T PT 2307458T
- Authority
- PT
- Portugal
- Prior art keywords
- humanization
- antibody framework
- rabbit antibodies
- universal antibody
- universal
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7569208P | 2008-06-25 | 2008-06-25 | |
| US7569708P | 2008-06-25 | 2008-06-25 | |
| US15510509P | 2009-02-24 | 2009-02-24 | |
| US15504109P | 2009-02-24 | 2009-02-24 | |
| CH8322009 | 2009-06-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2307458T true PT2307458T (en) | 2018-07-18 |
Family
ID=53532693
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT141626648T PT2752428T (en) | 2008-06-25 | 2009-06-25 | Humanization of rabbit antibodies using a universal antibody framework |
| PT97686950T PT2307458T (en) | 2008-06-25 | 2009-06-25 | Humanization of rabbit antibodies using a universal antibody framework |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT141626648T PT2752428T (en) | 2008-06-25 | 2009-06-25 | Humanization of rabbit antibodies using a universal antibody framework |
Country Status (9)
| Country | Link |
|---|---|
| JP (5) | JP2015120746A (en) |
| KR (2) | KR102284435B1 (en) |
| CL (1) | CL2010001539A1 (en) |
| ES (1) | ES2771150T3 (en) |
| HU (1) | HUE047678T2 (en) |
| PH (2) | PH12013502219A1 (en) |
| PT (2) | PT2752428T (en) |
| RU (2) | RU2696202C1 (en) |
| ZA (3) | ZA201008592B (en) |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE253593T1 (en) * | 1996-07-16 | 2003-11-15 | Plueckthun Andreas Prof Dr | IMMUNOGLOBULIN SUPERFAMILY DOMAINS AND FRAGMENTS WITH INCREASED SOLUBILITY |
| EP2044839A3 (en) * | 2000-08-03 | 2009-07-01 | Therapeutic Human Polyclonals, Inc. | Production of humanized antibodies in transgenic animals |
| AU2002303496A2 (en) * | 2001-04-25 | 2002-11-05 | Weigel, Janet A | Methods of using a hyaluronan receptor |
| AU2003217912A1 (en) * | 2002-03-01 | 2003-09-16 | Xencor | Antibody optimization |
| PT1506236E (en) * | 2002-05-22 | 2013-03-27 | Esbatech A Novartis Co Llc | Immunoglobulin frameworks which demonstrate enhanced stability in the intracellular environment and methods of identifying same |
| WO2004016740A2 (en) | 2002-08-15 | 2004-02-26 | Epitomics, Inc. | Humanized rabbit antibodies |
| CA2533830A1 (en) | 2003-08-07 | 2005-02-24 | Epitomics, Inc. | Methods for humanizing rabbit monoclonal antibodies |
| JP2007528723A (en) * | 2003-08-22 | 2007-10-18 | メディミューン，インコーポレーテッド | Antibody humanization |
| US7431927B2 (en) * | 2005-03-24 | 2008-10-07 | Epitomics, Inc. | TNFα-neutralizing antibodies |
| PT2390267E (en) * | 2005-06-07 | 2013-07-16 | Esbatech A Novartis Co Llc | Stable and soluble antibodies inhibiting tnf(alpha) |
| CN101948541B (en) * | 2005-06-20 | 2014-08-06 | 健泰科生物技术公司 | Compositions and methods for the diagnosis and treatment of tumor |
| GB0520436D0 (en) * | 2005-10-07 | 2005-11-16 | Photobiotics Ltd | Biological materials and uses thereof |
| WO2008004834A1 (en) * | 2006-07-06 | 2008-01-10 | Isu Abxis Co., Ltd | Humanized monoclonal antibody highly binding to epidermal growth factor receptor, egf receptor |
| EP2125894B1 (en) * | 2007-03-22 | 2018-12-19 | Biogen MA Inc. | Binding proteins, including antibodies, antibody derivatives and antibody fragments, that specifically bind cd154 and uses thereof |
-
2009
- 2009-06-25 ES ES14162664T patent/ES2771150T3/en active Active
- 2009-06-25 KR KR1020197022505A patent/KR102284435B1/en active IP Right Grant
- 2009-06-25 KR KR1020217023841A patent/KR20210097819A/en active Application Filing
- 2009-06-25 PT PT141626648T patent/PT2752428T/en unknown
- 2009-06-25 HU HUE14162664A patent/HUE047678T2/en unknown
- 2009-06-25 PT PT97686950T patent/PT2307458T/en unknown
-
2010
- 2010-11-30 ZA ZA2010/08592A patent/ZA201008592B/en unknown
- 2010-12-23 CL CL2010001539A patent/CL2010001539A1/en unknown
-
2013
- 2013-10-25 PH PH12013502219A patent/PH12013502219A1/en unknown
- 2013-11-21 ZA ZA2013/08755A patent/ZA201308755B/en unknown
-
2015
- 2015-03-18 JP JP2015054497A patent/JP2015120746A/en not_active Withdrawn
- 2015-05-11 ZA ZA2015/03267A patent/ZA201503267B/en unknown
-
2016
- 2016-04-27 JP JP2016088845A patent/JP2016135815A/en active Pending
-
2017
- 2017-07-31 JP JP2017148091A patent/JP6568557B2/en active Active
-
2018
- 2018-03-19 RU RU2018109506A patent/RU2696202C1/en active
- 2018-08-13 PH PH12018501715A patent/PH12018501715A1/en unknown
-
2019
- 2019-02-01 JP JP2019016882A patent/JP6903083B2/en active Active
- 2019-06-21 RU RU2019119412A patent/RU2019119412A/en unknown
-
2020
- 2020-04-30 JP JP2020080224A patent/JP2020114260A/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP2019065050A (en) | 2019-04-25 |
| JP2020114260A (en) | 2020-07-30 |
| PH12013502219A1 (en) | 2016-01-25 |
| RU2019119412A (en) | 2020-12-21 |
| PH12018501715A1 (en) | 2019-08-19 |
| JP2016135815A (en) | 2016-07-28 |
| KR20210097819A (en) | 2021-08-09 |
| JP6903083B2 (en) | 2021-07-14 |
| CL2010001539A1 (en) | 2012-02-03 |
| ZA201308755B (en) | 2015-08-26 |
| PT2752428T (en) | 2020-02-14 |
| JP2015120746A (en) | 2015-07-02 |
| RU2696202C1 (en) | 2019-07-31 |
| KR20190091578A (en) | 2019-08-06 |
| ES2771150T3 (en) | 2020-07-06 |
| ZA201503267B (en) | 2016-07-27 |
| JP6568557B2 (en) | 2019-08-28 |
| JP2017190352A (en) | 2017-10-19 |
| HUE047678T2 (en) | 2020-05-28 |
| KR102284435B1 (en) | 2021-08-02 |
| ZA201008592B (en) | 2014-02-26 |
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