PT2293804E - Vírus herpes simplex (hsv) com tropismo modificado, suas utilizações e processo de preparação - Google Patents
Vírus herpes simplex (hsv) com tropismo modificado, suas utilizações e processo de preparação Download PDFInfo
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- PT2293804E PT2293804E PT87899696T PT08789969T PT2293804E PT 2293804 E PT2293804 E PT 2293804E PT 87899696 T PT87899696 T PT 87899696T PT 08789969 T PT08789969 T PT 08789969T PT 2293804 E PT2293804 E PT 2293804E
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- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
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- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
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- C12N2810/00—Vectors comprising a targeting moiety
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- C12N2810/80—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates
- C12N2810/85—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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| US9593347B2 (en) | 2010-04-16 | 2017-03-14 | University of Pittsburgh—of the Commonwealth System of Higher Education | Identification of mutations in herpes simplex virus envelope glycoproteins that enable or enhance vector retargeting to novel non-HSV receptors |
| EP3184641B1 (en) | 2013-10-28 | 2020-07-08 | University of Pittsburgh - Of the Commonwealth System of Higher Education | Oncolytic hsv vector |
| WO2016128497A1 (en) * | 2015-02-11 | 2016-08-18 | Alma Mater Studiorum Universita' Di Bologna | Retargeted herpesvirus with a glycoprotein h fusion |
| SG11201806134SA (en) | 2016-01-27 | 2018-08-30 | Oncorus Inc | Oncolytic viral vectors and uses thereof |
| KR20190020727A (ko) * | 2016-06-09 | 2019-03-04 | 알마마 테르 스투디오룸 유니베르시타‘ 디 볼로냐 | 변형된 당단백질 b를 갖는 헤르페스 바이러스 |
| DK3469071T3 (da) * | 2016-06-09 | 2021-03-01 | Univ Bologna Alma Mater Studiorum | Herpesvirus med modificeret glycoprotein D |
| CA3029426A1 (en) | 2016-06-30 | 2018-01-04 | Oncorus, Inc. | Pseudotyped oncolytic viral delivery of therapeutic polypeptides |
| GB201616365D0 (en) * | 2016-09-27 | 2016-11-09 | Helsingin Yliopisto | Non-genetic modification of enveloped viruses |
| US11612625B2 (en) | 2017-07-26 | 2023-03-28 | Oncorus, Inc. | Oncolytic viral vectors and uses thereof |
| EP3677592B1 (en) * | 2017-08-30 | 2024-07-17 | KM Biologics Co., Ltd. | Modified hsv gd protein and vaccine containing same |
| JP2021508477A (ja) | 2017-12-29 | 2021-03-11 | オンコラス, インコーポレイテッド | 治療用ポリペプチドの腫瘍溶解性ウイルス送達 |
| EP3866924A4 (en) * | 2018-06-29 | 2022-07-06 | Krystal Biotech, Inc. | COMPOSITIONS AND METHODS OF ANTIBODY DELIVERY |
| EP3887529A4 (en) * | 2018-11-28 | 2022-08-31 | The Brigham & Women's Hospital, Inc. | NEXT GENERATION REGULABLE FUSOGENIC ONCOLYTIC HERPES SIMPLEX VIRUS TYPE 1 VIRUS AND METHODS OF USE |
| KR102686042B1 (ko) * | 2019-01-03 | 2024-07-17 | 앨버트 아인슈타인 컬리지 오브 메디신 | 재조합 단순 헤르페스 바이러스 2 (hsv-2) 백신 벡터를 사용한 면역의 수동 전달 |
| JP2023502099A (ja) * | 2019-11-18 | 2023-01-20 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド | コドン最適化された新世代の調節可能な融合性腫瘍溶解性単純ヘルペスウイルス1型ウイルスおよび使用方法 |
| CN115843313B (zh) * | 2020-06-12 | 2025-09-05 | 吉赛尔美德公司 | 用于多重靶向的重组单纯疱疹病毒及其用途 |
| CN112501137B (zh) * | 2020-11-11 | 2023-10-20 | 深圳先进技术研究院 | 一种神经环路标记系统 |
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| US6656718B2 (en) | 2000-07-07 | 2003-12-02 | Cancer Research Technology Limited | Modified carboxypeptidase enzymes and their use |
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| US20070243170A1 (en) * | 2002-10-07 | 2007-10-18 | The University Of Chicago | Targeting of Herpes Simplex Virus to Specific Receptors |
| ES2741523T3 (es) | 2002-10-07 | 2020-02-11 | Univ Chicago | Dirección del virus del herpes simple a receptores específicos |
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