PT2256500E - Utilização de inibidores da enzima tktl1 - Google Patents
Utilização de inibidores da enzima tktl1 Download PDFInfo
- Publication number
- PT2256500E PT2256500E PT100093236T PT10009323T PT2256500E PT 2256500 E PT2256500 E PT 2256500E PT 100093236 T PT100093236 T PT 100093236T PT 10009323 T PT10009323 T PT 10009323T PT 2256500 E PT2256500 E PT 2256500E
- Authority
- PT
- Portugal
- Prior art keywords
- agf
- mam
- individual
- patient
- tktl1
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 102000004190 Enzymes Human genes 0.000 title 1
- 108090000790 Enzymes Proteins 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 101000800498 Homo sapiens Transketolase-like protein 1 Proteins 0.000 abstract 2
- 102100033108 Transketolase-like protein 1 Human genes 0.000 abstract 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 239000012190 activator Substances 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- 238000000855 fermentation Methods 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 230000037353 metabolic pathway Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Diabetes (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Emergency Medicine (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05004930A EP1701165A1 (en) | 2005-03-07 | 2005-03-07 | Therapeutic and diagnostic uses of TKTL1 and inhibitors and activators thereof |
EP05013170 | 2005-06-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT2256500E true PT2256500E (pt) | 2014-07-18 |
Family
ID=36224891
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT100093236T PT2256500E (pt) | 2005-03-07 | 2006-03-03 | Utilização de inibidores da enzima tktl1 |
Country Status (11)
Country | Link |
---|---|
US (3) | US7754437B2 (pt) |
EP (2) | EP1856537B1 (pt) |
JP (1) | JP5095600B2 (pt) |
AT (1) | ATE509279T1 (pt) |
AU (1) | AU2006222277B2 (pt) |
CA (1) | CA2600206C (pt) |
DK (2) | DK2256500T3 (pt) |
ES (1) | ES2480416T3 (pt) |
PL (2) | PL1856537T3 (pt) |
PT (1) | PT2256500E (pt) |
WO (1) | WO2006094716A1 (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102007013903A1 (de) | 2007-03-20 | 2008-09-25 | Coy, Johannes F., Dr. | Getränk |
DE102010007243B4 (de) * | 2010-02-09 | 2011-11-17 | Frank Kischkel | Therapieoptimierung bei Krebspatienten durch Austesten von Therapiekombinationen mittels in vitro Testungen (Zusatz) |
DE102011008016A1 (de) | 2011-01-06 | 2012-07-12 | Johannes F. Coy | Schokoladenmasse |
DE102020116980A1 (de) | 2020-06-27 | 2021-12-30 | TAVARGENIX GmbH | Verwendung von Co-Enzym-Antagonisten zur Stoffwechselverlangsamung |
CN112730734A (zh) * | 2020-12-22 | 2021-04-30 | 河南星汉生物科技有限公司 | 一种葡萄糖发酵乳酸中发酵液残糖的检验方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4006219A (en) * | 1972-08-10 | 1977-02-01 | Ceres Pharmacal Company | Composition and method for countering effects of alcohol consumption |
DE2834706A1 (de) * | 1978-08-08 | 1980-02-14 | Boehringer Mannheim Gmbh | Verfahren und reagens zur bestimmung von glutamat-oxalacetat-transaminase und glutamat-pyruvat-transaminase |
US4594237A (en) * | 1984-04-16 | 1986-06-10 | Walter Ziegler | Method for testing chemical and biological substances |
EP1290186A2 (en) * | 2000-05-31 | 2003-03-12 | Bayer Aktiengesellschaft | Regulation of a human transketolase-like enzyme |
US7381713B2 (en) * | 2000-12-04 | 2008-06-03 | Sioan-Kettering Institute For Cancer Research | Treatment of cancer by reduction of intracellular energy and pyrimidines |
ES2298304T3 (es) * | 2002-04-19 | 2008-05-16 | Johannes Dr. Coy | Composiciones y procedimientos para la deteccion y tratamiento de anormalidades proliferativas asociadas con la sobreexpresion de gen like-1 de transcetolasa humano. |
-
2006
- 2006-03-03 AU AU2006222277A patent/AU2006222277B2/en active Active
- 2006-03-03 PL PL06723195T patent/PL1856537T3/pl unknown
- 2006-03-03 EP EP06723195A patent/EP1856537B1/en active Active
- 2006-03-03 ES ES10009323.6T patent/ES2480416T3/es active Active
- 2006-03-03 WO PCT/EP2006/001951 patent/WO2006094716A1/en not_active Application Discontinuation
- 2006-03-03 PL PL10009323T patent/PL2256500T3/pl unknown
- 2006-03-03 DK DK10009323.6T patent/DK2256500T3/da active
- 2006-03-03 PT PT100093236T patent/PT2256500E/pt unknown
- 2006-03-03 AT AT06723195T patent/ATE509279T1/de active
- 2006-03-03 EP EP10009323.6A patent/EP2256500B1/en active Active
- 2006-03-03 US US11/571,205 patent/US7754437B2/en active Active
- 2006-03-03 JP JP2008500098A patent/JP5095600B2/ja active Active
- 2006-03-03 CA CA2600206A patent/CA2600206C/en active Active
- 2006-03-03 DK DK06723195.1T patent/DK1856537T3/da active
-
2010
- 2010-05-28 US US12/790,257 patent/US11236381B2/en active Active
-
2020
- 2020-01-29 US US16/775,454 patent/US11359225B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
PL1856537T3 (pl) | 2011-10-31 |
US7754437B2 (en) | 2010-07-13 |
PL2256500T3 (pl) | 2014-10-31 |
CA2600206C (en) | 2011-01-04 |
ES2480416T3 (es) | 2014-07-28 |
US20080095703A1 (en) | 2008-04-24 |
EP1856537B1 (en) | 2011-05-11 |
CA2600206A1 (en) | 2006-09-14 |
EP2256500A3 (en) | 2012-08-29 |
DK1856537T3 (da) | 2011-07-18 |
EP1856537A1 (en) | 2007-11-21 |
ATE509279T1 (de) | 2011-05-15 |
US20200248227A1 (en) | 2020-08-06 |
EP2256500B1 (en) | 2014-04-23 |
AU2006222277A1 (en) | 2006-09-14 |
US20100240687A1 (en) | 2010-09-23 |
JP2008531065A (ja) | 2008-08-14 |
EP2256500A2 (en) | 2010-12-01 |
US11236381B2 (en) | 2022-02-01 |
WO2006094716A1 (en) | 2006-09-14 |
AU2006222277B2 (en) | 2011-04-07 |
DK2256500T3 (da) | 2014-07-14 |
JP5095600B2 (ja) | 2012-12-12 |
US11359225B2 (en) | 2022-06-14 |
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