PT2164868E - Domínios variáveis de anticorpos de coelho manipulados e suas utilizações - Google Patents

Domínios variáveis de anticorpos de coelho manipulados e suas utilizações Download PDF

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Publication number
PT2164868E
PT2164868E PT87538641T PT08753864T PT2164868E PT 2164868 E PT2164868 E PT 2164868E PT 87538641 T PT87538641 T PT 87538641T PT 08753864 T PT08753864 T PT 08753864T PT 2164868 E PT2164868 E PT 2164868E
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PT
Portugal
Prior art keywords
variable domains
antibody variable
rabbit antibody
engineered
engineered rabbit
Prior art date
Application number
PT87538641T
Other languages
English (en)
Portuguese (pt)
Inventor
Frederico Nuno Castanheira Aires Da Silva
João Manuel Braz Goncalves
Original Assignee
Technophage Investigaçao E Desenvolvimento Em Biotecnologia Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technophage Investigaçao E Desenvolvimento Em Biotecnologia Sa filed Critical Technophage Investigaçao E Desenvolvimento Em Biotecnologia Sa
Publication of PT2164868E publication Critical patent/PT2164868E/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567Framework region [FR]

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
PT87538641T 2007-05-04 2008-04-30 Domínios variáveis de anticorpos de coelho manipulados e suas utilizações PT2164868E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US91622607P 2007-05-04 2007-05-04

Publications (1)

Publication Number Publication Date
PT2164868E true PT2164868E (pt) 2015-08-04

Family

ID=39735911

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87538641T PT2164868E (pt) 2007-05-04 2008-04-30 Domínios variáveis de anticorpos de coelho manipulados e suas utilizações

Country Status (9)

Country Link
US (2) US10280211B2 (https=)
EP (1) EP2164868B1 (https=)
JP (3) JP5791895B2 (https=)
AU (1) AU2008246442B2 (https=)
CA (1) CA2685213C (https=)
ES (1) ES2540807T3 (https=)
PT (1) PT2164868E (https=)
SG (1) SG194368A1 (https=)
WO (1) WO2008136694A1 (https=)

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US11685773B2 (en) 2015-04-30 2023-06-27 Abcheck S.R.O. Method for mass humanization of rabbit antibodies
SMT202000633T1 (it) * 2015-06-19 2021-01-05 Eisai R&D Man Co Ltd Immunoglobuline coniugate a cys80
US20210221915A1 (en) * 2018-06-08 2021-07-22 Ventana Medical Systems, Inc. Universal or normalized antibody frameworks for improved functionality and manufacturability
CA3231704A1 (en) * 2021-09-13 2023-03-16 The Board Of Regents Of The University Of Texas System Trem2 antigen binding proteins and uses thereof

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Also Published As

Publication number Publication date
AU2008246442A1 (en) 2008-11-13
WO2008136694A9 (en) 2010-09-02
ES2540807T3 (es) 2015-07-13
EP2164868A1 (en) 2010-03-24
CA2685213C (en) 2017-02-21
WO2008136694A1 (en) 2008-11-13
JP2010525808A (ja) 2010-07-29
SG194368A1 (en) 2013-11-29
US10280211B2 (en) 2019-05-07
CA2685213A1 (en) 2008-11-13
JP2015164940A (ja) 2015-09-17
US20190256578A1 (en) 2019-08-22
US20100136627A1 (en) 2010-06-03
EP2164868B1 (en) 2015-03-25
JP5791895B2 (ja) 2015-10-07
JP2015012869A (ja) 2015-01-22
AU2008246442B2 (en) 2014-07-03

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