PT2152195E - Produto farmacêutico peptídico para distribuição oral - Google Patents

Produto farmacêutico peptídico para distribuição oral Download PDF

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Publication number
PT2152195E
PT2152195E PT87679361T PT08767936T PT2152195E PT 2152195 E PT2152195 E PT 2152195E PT 87679361 T PT87679361 T PT 87679361T PT 08767936 T PT08767936 T PT 08767936T PT 2152195 E PT2152195 E PT 2152195E
Authority
PT
Portugal
Prior art keywords
oral delivery
peptide pharmaceutical
peptide
pharmaceutical
oral
Prior art date
Application number
PT87679361T
Other languages
English (en)
Inventor
Angelo P Consalvo
William Stern
Original Assignee
Enteris Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40093991&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2152195(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Enteris Biopharma Inc filed Critical Enteris Biopharma Inc
Publication of PT2152195E publication Critical patent/PT2152195E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2235—Secretins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT87679361T 2007-05-29 2008-05-29 Produto farmacêutico peptídico para distribuição oral PT2152195E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94059807P 2007-05-29 2007-05-29
US12/128,210 US8377863B2 (en) 2007-05-29 2008-05-28 Peptide pharmaceutical for oral delivery

Publications (1)

Publication Number Publication Date
PT2152195E true PT2152195E (pt) 2016-02-08

Family

ID=40093991

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87679361T PT2152195E (pt) 2007-05-29 2008-05-29 Produto farmacêutico peptídico para distribuição oral

Country Status (10)

Country Link
US (6) US8377863B2 (pt)
EP (2) EP3009129B1 (pt)
JP (1) JP5365629B2 (pt)
CN (1) CN101801309B (pt)
AU (1) AU2008260615B9 (pt)
CA (1) CA2689358C (pt)
DK (1) DK2152195T3 (pt)
ES (1) ES2560251T3 (pt)
PT (1) PT2152195E (pt)
WO (1) WO2008150426A1 (pt)

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US8088734B2 (en) * 2003-01-21 2012-01-03 Unigene Laboratories Inc. Oral delivery of peptides
US20050282756A1 (en) 2004-06-18 2005-12-22 Mehta Nozer M Oral delivery of peptide pharmaceutical compositions
US8377863B2 (en) 2007-05-29 2013-02-19 Unigene Laboratories Inc. Peptide pharmaceutical for oral delivery
DK2389388T3 (en) 2009-01-22 2017-05-01 Keybioscience Ag TREATMENT FOR Obesity
KR20130094293A (ko) * 2010-07-21 2013-08-23 알콘 리서치, 리미티드 향상된 용해도 특성들을 갖는 약학 조성물
JP5715425B2 (ja) * 2011-01-24 2015-05-07 株式会社ネットステップ 光ネットワークの障害監視検出装置、方法、プログラム及びシステム
ES2712805T3 (es) 2011-06-15 2019-05-14 Resother Pharma Aps Næsseslottet Productos farmacéuticos antiinflamatorios
HUE039105T2 (hu) 2011-11-02 2018-12-28 Keybioscience Ag Kalcitonin mimetikumok betegségek és rendellenességek kezelésére
KR102019911B1 (ko) 2011-11-02 2019-09-09 키바이오사이언스 아게 질병 및 장애 치료용 펩타이드 유사체
WO2013148966A1 (en) * 2012-03-28 2013-10-03 Amylin Pharmaceuticals, Llc Transmucosal delivery of engineered polypeptides
CN104853749A (zh) * 2012-09-17 2015-08-19 塔瑞克斯制药有限公司 血管紧张素的口服制剂
WO2014102741A2 (en) 2012-12-28 2014-07-03 University Of The Witwatersrand, Johannesburg Pharmaceutical dosage form
ES2774962T3 (es) 2013-03-05 2020-07-23 Enteris Biopharma Inc Productos farmacéuticos de administración oral
US10232021B2 (en) 2013-11-14 2019-03-19 Keybioscience Ag Calcitonin mimetics for treating diseases and disorders
CN105475588A (zh) * 2014-10-13 2016-04-13 罗盖特公司 包括包衣酸的压制片
GB201500263D0 (en) 2015-01-08 2015-02-25 Keybioscience Ag Calcitonin analogues for treating diseases and disorders
DK3244878T3 (da) * 2015-01-12 2022-10-17 Enteris Biopharma Inc Faste orale sammensætningsformer
RU2019105756A (ru) * 2016-08-05 2020-09-08 ТАУРУС ДИВЕЛОПМЕНТ КОМПАНИ ЭлЭлСи Стабильный при комнатной температуре пероральный состав кальцитонина
GB201704429D0 (en) 2017-03-21 2017-05-03 Keybioscience Ag Calcitonin mimetics for treating diseases and disorders
GB201707955D0 (en) 2017-05-18 2017-07-05 Keybioscience Ag Dual amylin and calcitonin receptor agonists for treating diseases and disorders
CN108065443B (zh) * 2017-12-30 2020-02-28 厦门金达威维生素有限公司 斥水型双包被微胶囊及其制备方法
EP3610862A1 (en) * 2018-08-14 2020-02-19 Apillet APS Novel oral composition
GB201813678D0 (en) 2018-08-22 2018-10-03 Keybioscience Ag Acylated calcitonin mimetics
GB201813677D0 (en) 2018-08-22 2018-10-03 Keybioscience Ag Calcitonin mimetics for treating diseases and disorders
KR102664288B1 (ko) 2018-09-14 2024-05-09 케러 테라퓨틱스, 인코포레이티드 카파 오피오이드 수용체 효능제의 경구 제형
WO2020257260A1 (en) 2019-06-17 2020-12-24 Massachusetts Institute Of Technology Formulation of peptide loaded liposomes and related applications
IL296368A (en) 2020-03-18 2022-11-01 Cara Therapeutics Inc Oligosaccharide formulations of kappa opioid receptor agonists
EP4226918A1 (en) 2022-02-15 2023-08-16 Filip Majewski Pharmaceutical single dosage form for oral delivery of peptides
WO2023245016A1 (en) 2022-06-13 2023-12-21 B.A.I. Laboratories, Llc Interleukin-13 binding cyclic oligopeptides and methods of use thereof

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US8088734B2 (en) 2003-01-21 2012-01-03 Unigene Laboratories Inc. Oral delivery of peptides
US20050123507A1 (en) 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
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KR20050104152A (ko) 2004-04-28 2005-11-02 최승호 경구용 약물의 흡수를 증진하는 약제학적 조성물
US20050282756A1 (en) 2004-06-18 2005-12-22 Mehta Nozer M Oral delivery of peptide pharmaceutical compositions
US7445911B2 (en) 2004-11-24 2008-11-04 Unigene Laboratories Inc. Enzymatic reactions in the presence of keto acids
EP1907561B1 (en) 2005-06-24 2013-08-28 Unigene Laboratories, Inc. Cell lines for expressing enzyme useful in the preparation of amidated products
US8093207B2 (en) 2005-12-09 2012-01-10 Unigene Laboratories, Inc. Fast-acting oral peptide pharmaceutical products
US8377863B2 (en) 2007-05-29 2013-02-19 Unigene Laboratories Inc. Peptide pharmaceutical for oral delivery
US20120071410A1 (en) 2010-09-21 2012-03-22 Unigene Laboratories Inc. Calcitonin products and therapies for treating inflammatory or degenerative diseases
ES2712805T3 (es) 2011-06-15 2019-05-14 Resother Pharma Aps Næsseslottet Productos farmacéuticos antiinflamatorios
ES2774962T3 (es) 2013-03-05 2020-07-23 Enteris Biopharma Inc Productos farmacéuticos de administración oral

Also Published As

Publication number Publication date
US9399017B2 (en) 2016-07-26
JP5365629B2 (ja) 2013-12-11
EP3009129A1 (en) 2016-04-20
CA2689358C (en) 2012-11-27
EP2152195B1 (en) 2015-11-11
US8513183B2 (en) 2013-08-20
CN101801309B (zh) 2013-05-08
US20090317462A1 (en) 2009-12-24
AU2008260615B2 (en) 2011-10-06
EP2152195A1 (en) 2010-02-17
DK2152195T3 (en) 2016-02-15
US8664178B2 (en) 2014-03-04
CN101801309A (zh) 2010-08-11
CA2689358A1 (en) 2008-12-11
US8592366B2 (en) 2013-11-26
JP2010529018A (ja) 2010-08-26
US20130034600A1 (en) 2013-02-07
ES2560251T3 (es) 2016-02-18
US8377863B2 (en) 2013-02-19
US20160339081A1 (en) 2016-11-24
US20120315325A1 (en) 2012-12-13
AU2008260615B9 (en) 2011-10-13
US20140335169A1 (en) 2014-11-13
AU2008260615A1 (en) 2008-12-11
US20120040000A1 (en) 2012-02-16
WO2008150426A1 (en) 2008-12-11
EP3009129B1 (en) 2017-08-09
EP2152195A4 (en) 2012-10-31

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