PT2101731T - Endoxifeno para utilização no tratamento de cancro - Google Patents
Endoxifeno para utilização no tratamento de cancroInfo
- Publication number
- PT2101731T PT2101731T PT78715638T PT07871563T PT2101731T PT 2101731 T PT2101731 T PT 2101731T PT 78715638 T PT78715638 T PT 78715638T PT 07871563 T PT07871563 T PT 07871563T PT 2101731 T PT2101731 T PT 2101731T
- Authority
- PT
- Portugal
- Prior art keywords
- endoxifen
- cancer
- treatment
- Prior art date
Links
- MHJBZVSGOZTKRH-IZHYLOQSSA-N 4-Hydroxy-N-desmethyltamoxifen Chemical compound C=1C=CC=CC=1C(/CC)=C(C=1C=CC(OCCNC)=CC=1)/C1=CC=C(O)C=C1 MHJBZVSGOZTKRH-IZHYLOQSSA-N 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Pyrane Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86042006P | 2006-11-21 | 2006-11-21 | |
| US86078806P | 2006-11-22 | 2006-11-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2101731T true PT2101731T (pt) | 2018-04-18 |
Family
ID=39492975
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT78715638T PT2101731T (pt) | 2006-11-21 | 2007-11-21 | Endoxifeno para utilização no tratamento de cancro |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US9333190B2 (enExample) |
| EP (1) | EP2101731B1 (enExample) |
| JP (1) | JP2010510327A (enExample) |
| CA (1) | CA2669913C (enExample) |
| DK (1) | DK2101731T3 (enExample) |
| ES (1) | ES2665917T3 (enExample) |
| HU (1) | HUE037109T2 (enExample) |
| IN (1) | IN2014MN00139A (enExample) |
| PL (1) | PL2101731T3 (enExample) |
| PT (1) | PT2101731T (enExample) |
| WO (1) | WO2008070463A2 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090291134A1 (en) * | 2006-11-21 | 2009-11-26 | Jina Pharmaceuticals, Inc. | Endoxifen methods and compositions in the treatment of psychiatric and neurodegenerative diseases |
| PL2101731T3 (pl) | 2006-11-21 | 2018-07-31 | Jina Pharmaceuticals Inc. | Endoksyfen do zastosowania w leczeniu nowotworu |
| DK2373305T3 (en) * | 2008-12-11 | 2017-05-15 | Besins Healthcare Lu Sarl | TRANSDERMAL PHARMACEUTICAL COMPOSITIONS INCLUDING A SERM |
| AU2012247545B2 (en) | 2011-04-28 | 2016-08-11 | Oncopeptides Innovation Ab | Lyophilized preparation of cytotoxic dipeptides |
| EP2668945A1 (de) | 2012-06-01 | 2013-12-04 | Bayer Technology Services GmbH | Genotyp- bzw. Phänotyp-basierte Arzeimittelformulierungen |
| JP6284945B2 (ja) * | 2012-10-26 | 2018-02-28 | オンコペプティデス エービーＯｎｃｏｐｅｐｔｉｄｅｓ ＡＢ | メルファランフルフェナミドの凍結乾燥製剤 |
| WO2017011623A1 (en) * | 2015-07-14 | 2017-01-19 | Atossa Genetics Inc. | Transpapillary methods and compositions for treating breast disorders |
| DE102015222031A1 (de) | 2015-11-10 | 2017-05-11 | Robert Bosch Gesellschaft Für Medizinische Forschung Mbh | Synthese von (Z)-Endoxifenhydrochlorid |
| US20170304232A1 (en) * | 2016-04-20 | 2017-10-26 | Northwestern University | Endoxifen For Local Transdermal Therapy To The Breast |
| EP3681478B1 (en) * | 2017-09-11 | 2025-09-10 | Atossa Therapeutics, Inc. | Topical compositions and methods for treatment |
| TWI793165B (zh) | 2017-09-11 | 2023-02-21 | 美商阿托薩醫療公司 | 製造及使用因多昔芬(endoxifen)之方法 |
| US12201591B2 (en) | 2019-07-03 | 2025-01-21 | Atossa Therapeutics, Inc. | Sustained release compositions of endoxifen |
| US11291640B2 (en) | 2020-04-10 | 2022-04-05 | Jina Pharmaceuticals, Inc. | Endoxifen for the treatment of bipolar I disorder |
| US12245997B2 (en) | 2020-04-10 | 2025-03-11 | Jina Pharmaceuticals, Inc. | Endoxifen for the treatment of bipolar I disorder |
| TW202302072A (zh) * | 2021-03-18 | 2023-01-16 | 國立臺灣大學 | 用於親水帶電化合物的脂質奈米顆粒遞送系統 |
| EP4463437A2 (en) | 2022-01-12 | 2024-11-20 | Atossa Therapeutics, Inc. | Compositions of (z)-endoxifen and methods of enrichment thereof |
| WO2023211939A1 (en) * | 2022-04-26 | 2023-11-02 | Atossa Therapeutics, Inc. | High dose endoxifen formulations and methods of use |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2817157A1 (de) * | 1978-04-17 | 1979-10-25 | Schering Ag | Verwendung von antioestrogenen und antigonadotrop wirkenden antiandrogenen zur prophylaxe und therapie der prostatahyperplasie |
| US6290991B1 (en) * | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
| CA2197982C (en) * | 1994-08-04 | 2010-03-23 | Bruce Joseph Roser | Solid delivery systems for controlled release of molecules incorporated therein and methods of making same |
| ATE345682T1 (de) * | 1996-05-01 | 2006-12-15 | Imarx Pharmaceutical Corp | In vitro verfahren zum einbringen von nukleinsäuren in eine zelle |
| US6090407A (en) * | 1997-09-23 | 2000-07-18 | Research Development Foundation | Small particle liposome aerosols for delivery of anti-cancer drugs |
| US7968532B2 (en) | 2003-12-15 | 2011-06-28 | Besins Healthcare Luxembourg | Treatment of gynecomastia with 4-hydroxy tamoxifen |
| DK2076244T3 (en) | 2006-10-10 | 2017-02-27 | Jina Pharmaceuticals Inc | Aqueous systems for the preparation of lipid-based pharmaceutical compounds; compositions, methods and uses thereof |
| WO2008048194A1 (en) | 2006-10-20 | 2008-04-24 | Yesilogluj Aysegul Yildiz | Use of the protein kinase c inhibitor tamoxifen for the treatment of bipolar disorder |
| WO2008058156A2 (en) | 2006-11-06 | 2008-05-15 | Jina Pharmaceuticals Inc. | Guggulphospholipid methods and compositions |
| US20090291134A1 (en) * | 2006-11-21 | 2009-11-26 | Jina Pharmaceuticals, Inc. | Endoxifen methods and compositions in the treatment of psychiatric and neurodegenerative diseases |
| PL2101731T3 (pl) | 2006-11-21 | 2018-07-31 | Jina Pharmaceuticals Inc. | Endoksyfen do zastosowania w leczeniu nowotworu |
| JP5720881B2 (ja) | 2011-01-31 | 2015-05-20 | 東芝ライテック株式会社 | Ｌｅｄランプ点灯装置および照明装置 |
-
2007
- 2007-11-21 PL PL07871563T patent/PL2101731T3/pl unknown
- 2007-11-21 HU HUE07871563A patent/HUE037109T2/hu unknown
- 2007-11-21 EP EP07871563.8A patent/EP2101731B1/en not_active Revoked
- 2007-11-21 DK DK07871563.8T patent/DK2101731T3/en active
- 2007-11-21 CA CA2669913A patent/CA2669913C/en active Active
- 2007-11-21 IN IN139MUN2014 patent/IN2014MN00139A/en unknown
- 2007-11-21 US US12/515,261 patent/US9333190B2/en active Active
- 2007-11-21 PT PT78715638T patent/PT2101731T/pt unknown
- 2007-11-21 ES ES07871563.8T patent/ES2665917T3/es active Active
- 2007-11-21 JP JP2009538518A patent/JP2010510327A/ja active Pending
- 2007-11-21 WO PCT/US2007/085443 patent/WO2008070463A2/en not_active Ceased
-
2016
- 2016-04-27 US US15/139,687 patent/US10376479B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US9333190B2 (en) | 2016-05-10 |
| US10376479B2 (en) | 2019-08-13 |
| WO2008070463A3 (en) | 2008-11-06 |
| US20100112041A1 (en) | 2010-05-06 |
| PL2101731T3 (pl) | 2018-07-31 |
| ES2665917T3 (es) | 2018-04-30 |
| WO2008070463A2 (en) | 2008-06-12 |
| JP2010510327A (ja) | 2010-04-02 |
| DK2101731T3 (en) | 2018-04-16 |
| CA2669913A1 (en) | 2008-06-12 |
| EP2101731B1 (en) | 2018-01-31 |
| CA2669913C (en) | 2012-09-18 |
| IN2014MN00139A (enExample) | 2015-06-19 |
| WO2008070463A9 (en) | 2008-09-18 |
| HUE037109T2 (hu) | 2018-08-28 |
| EP2101731A2 (en) | 2009-09-23 |
| EP2101731A4 (en) | 2011-04-20 |
| US20160346230A1 (en) | 2016-12-01 |
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