PT2076532E - Derivados de citocina - Google Patents

Derivados de citocina Download PDF

Info

Publication number
PT2076532E
PT2076532E PT07825334T PT07825334T PT2076532E PT 2076532 E PT2076532 E PT 2076532E PT 07825334 T PT07825334 T PT 07825334T PT 07825334 T PT07825334 T PT 07825334T PT 2076532 E PT2076532 E PT 2076532E
Authority
PT
Portugal
Prior art keywords
seq
hiv
agents
polypeptide
gin
Prior art date
Application number
PT07825334T
Other languages
English (en)
Portuguese (pt)
Inventor
Oliver Hartley
Original Assignee
Mintaka Foundation For Medical Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mintaka Foundation For Medical Res filed Critical Mintaka Foundation For Medical Res
Publication of PT2076532E publication Critical patent/PT2076532E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/521Chemokines
    • C07K14/523Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Neurosurgery (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • AIDS & HIV (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
PT07825334T 2006-07-25 2007-07-25 Derivados de citocina PT2076532E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0614755.7A GB0614755D0 (en) 2006-07-25 2006-07-25 Cytokine derivatives

Publications (1)

Publication Number Publication Date
PT2076532E true PT2076532E (pt) 2011-03-02

Family

ID=37006114

Family Applications (1)

Application Number Title Priority Date Filing Date
PT07825334T PT2076532E (pt) 2006-07-25 2007-07-25 Derivados de citocina

Country Status (25)

Country Link
US (2) US8686111B2 (https=)
EP (1) EP2076532B1 (https=)
JP (1) JP5224603B2 (https=)
KR (1) KR101530353B1 (https=)
CN (1) CN101511867B (https=)
AT (1) ATE490270T1 (https=)
AU (1) AU2007278894B2 (https=)
BR (1) BRPI0715331B8 (https=)
CA (1) CA2658806C (https=)
CY (1) CY1111630T1 (https=)
DE (1) DE602007010969D1 (https=)
DK (1) DK2076532T3 (https=)
ES (1) ES2361455T3 (https=)
GB (1) GB0614755D0 (https=)
HR (1) HRP20110146T1 (https=)
ME (1) ME01320B (https=)
MX (1) MX2009000918A (https=)
NZ (1) NZ575092A (https=)
PL (1) PL2076532T3 (https=)
PT (1) PT2076532E (https=)
RS (1) RS51854B (https=)
RU (1) RU2461567C2 (https=)
SI (1) SI2076532T1 (https=)
WO (1) WO2008012689A2 (https=)
ZA (1) ZA200901342B (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT201600091033A1 (it) * 2016-09-08 2018-03-08 Bioimmunizer Sagl Ceppi di batteri probiotici appartenenti al genere Bifidobacterium e loro estratti di cellule probiotiche (ECP) aventi proprietà immunostimolanti.
KR20210016398A (ko) * 2018-05-28 2021-02-15 오리온 바이오테크놀로지 스윗졀랜드 에스아에흐엘 암 치료에 사용하기 위한 ccr5 억제제
CN112469430B (zh) * 2018-05-28 2024-12-24 日内瓦大学 抑制大脑炎症的方法
EP4646232A1 (en) 2023-01-06 2025-11-12 Université de Genève Variant ligand conjugates for payload delivery
WO2025172252A1 (en) 2024-02-15 2025-08-21 Novo Nordisk A/S Protracted ccr5 antagonists and uses thereof
WO2025176787A1 (en) 2024-02-22 2025-08-28 Orion Biotechnology Holding Sa Ccl5 variants for modulating gpr75
WO2025186255A1 (en) 2024-03-06 2025-09-12 Orion Biotechnology Holding Sa Gipr inhibitors and methods of use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2164818C (en) * 1993-06-09 2003-09-23 Charles D.Y. Sia Tandem synthetic hiv-1 peptides
FR2748938B1 (fr) * 1996-05-22 1998-07-31 Pasteur Institut Utilisation de molecules antagonistes de chemokines pour leur activite antivirale notamment contre un retrovirus de type vih
UA77950C2 (en) 2000-10-04 2007-02-15 Applied Research Systems Use of mutants of cc chemokines for treatment of multiple sclerosis
US20030049603A1 (en) * 2001-09-05 2003-03-13 Guy Gorochov Methods for construction and screening of libraries of chemokine variants
US7442512B2 (en) * 2001-11-30 2008-10-28 Chemocentryx, Inc. Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors
WO2005112567A2 (en) 2004-05-03 2005-12-01 University Of Maryland Biotechnology Institute Vaginal microbicide

Also Published As

Publication number Publication date
HK1131162A1 (en) 2010-01-15
HRP20110146T1 (hr) 2011-06-30
ME01320B (me) 2013-12-20
BRPI0715331B8 (pt) 2021-05-25
DK2076532T3 (da) 2011-03-07
US20090317363A1 (en) 2009-12-24
US20130330305A1 (en) 2013-12-12
JP2009544304A (ja) 2009-12-17
MX2009000918A (es) 2009-08-26
RU2461567C2 (ru) 2012-09-20
EP2076532A2 (en) 2009-07-08
DE602007010969D1 (de) 2011-01-13
WO2008012689A2 (en) 2008-01-31
BRPI0715331B1 (pt) 2021-04-13
CA2658806A1 (en) 2008-01-31
AU2007278894B2 (en) 2012-08-09
CA2658806C (en) 2017-01-03
SI2076532T1 (sl) 2011-06-30
KR101530353B1 (ko) 2015-06-26
WO2008012689A3 (en) 2008-05-08
US8686111B2 (en) 2014-04-01
KR20090060281A (ko) 2009-06-11
RU2009106436A (ru) 2010-08-27
ES2361455T3 (es) 2011-06-17
AU2007278894A1 (en) 2008-01-31
JP5224603B2 (ja) 2013-07-03
CN101511867B (zh) 2014-04-09
BRPI0715331A2 (pt) 2013-07-16
CY1111630T1 (el) 2015-10-07
NZ575092A (en) 2011-08-26
EP2076532B1 (en) 2010-12-01
RS51854B (sr) 2012-02-29
ATE490270T1 (de) 2010-12-15
ZA200901342B (en) 2010-11-24
US9328153B2 (en) 2016-05-03
CN101511867A (zh) 2009-08-19
GB0614755D0 (en) 2006-09-06
PL2076532T3 (pl) 2011-07-29

Similar Documents

Publication Publication Date Title
US9328153B2 (en) Cytokine derivatives
ES2273492T3 (es) Peptidos antagonistas de il-6.
CN108431023B (zh) 治疗黑皮质素-4受体途径相关病症的方法
US9346871B2 (en) Engineered CXCL12 alpha locked dimer polypeptide
JP2001515845A (ja) Rantesのn末端の修飾および使用方法
KR102389792B1 (ko) Hiv를 강력하게 저해하는 리포펩티드, 그의 유도체, 그의 약학적 조성물 및 그의 용도
ITMI982441A1 (it) Peptidi derivati da rantes con attivita' anti-hiv.
WO2013127300A1 (zh) 用于抑制hiv的多肽、其药物组合物及其用途
HK1131162B (en) Cytokine derivatives
TW200524625A (en) Antiviral compositions which inhibit paramyxovirus infection
CN120399096B (zh) 靶向CCR5和gp41的双功能融合蛋白及其在制备抗人类免疫缺陷病毒的药物中的应用
KR101138930B1 (ko) Hⅰv nc 단백질을 포함하는 aⅰds 예방 및 치료용조성물
CN118684745A (zh) 一种抗hiv-1多肽及其衍生物和应用
WO2023225802A1 (zh) 三叶因子2/干扰素α2融合蛋白及其防治病毒感染性疾病的应用
Boykins et al. Chemical synthesis and characterization of chemokine RANTES and its analogues
WO2013127299A1 (zh) 用于抑制hiv的多肽及其作用靶点
WO2024125271A1 (zh) 抗hiv-1的重组蛋白及其应用