BRPI0715331B8 - polipeptídeo que compreende uma porção n-terminal e uma porção c-terminal, e uso do mesmo - Google Patents

polipeptídeo que compreende uma porção n-terminal e uma porção c-terminal, e uso do mesmo

Info

Publication number
BRPI0715331B8
BRPI0715331B8 BRPI0715331A BRPI0715331A BRPI0715331B8 BR PI0715331 B8 BRPI0715331 B8 BR PI0715331B8 BR PI0715331 A BRPI0715331 A BR PI0715331A BR PI0715331 A BRPI0715331 A BR PI0715331A BR PI0715331 B8 BRPI0715331 B8 BR PI0715331B8
Authority
BR
Brazil
Prior art keywords
terminal portion
polypeptide
polypeptides
seq
amino acid
Prior art date
Application number
BRPI0715331A
Other languages
English (en)
Inventor
Hartley Olivier
Original Assignee
Mintaka Foundation For Medical Res
ORION Biotechnology Switzerland Sarl
The Mintaka Medical Res Foudation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mintaka Foundation For Medical Res, ORION Biotechnology Switzerland Sarl, The Mintaka Medical Res Foudation filed Critical Mintaka Foundation For Medical Res
Publication of BRPI0715331A2 publication Critical patent/BRPI0715331A2/pt
Publication of BRPI0715331B1 publication Critical patent/BRPI0715331B1/pt
Publication of BRPI0715331B8 publication Critical patent/BRPI0715331B8/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/521Chemokines
    • C07K14/523Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • AIDS & HIV (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)

Abstract

derivados de citoquina. a presente invenção refere-se a polipeptídeos que compreendem uma parcela n-terminal e uma parcela c-termina, sendo que cada parcela n-terminal compreende a sequência de assinatura qgp[p ou l] e a seuquência de aminoácido da referida parcela c- terminal é pelo menos 70% idêntica à seq in no: 1, seus empregos.
BRPI0715331A 2006-07-25 2007-07-25 polipeptídeo que compreende uma porção n-terminal e uma porção c-terminal, e uso do mesmo BRPI0715331B8 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB0614755.7A GB0614755D0 (en) 2006-07-25 2006-07-25 Cytokine derivatives
GB0614755.7 2006-07-25
GB06147557 2006-07-25
PCT/IB2007/003026 WO2008012689A2 (en) 2006-07-25 2007-07-25 Cytokine derivatives

Publications (3)

Publication Number Publication Date
BRPI0715331A2 BRPI0715331A2 (pt) 2013-07-16
BRPI0715331B1 BRPI0715331B1 (pt) 2021-04-13
BRPI0715331B8 true BRPI0715331B8 (pt) 2021-05-25

Family

ID=37006114

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0715331A BRPI0715331B8 (pt) 2006-07-25 2007-07-25 polipeptídeo que compreende uma porção n-terminal e uma porção c-terminal, e uso do mesmo

Country Status (26)

Country Link
US (2) US8686111B2 (pt)
EP (1) EP2076532B1 (pt)
JP (1) JP5224603B2 (pt)
KR (1) KR101530353B1 (pt)
CN (1) CN101511867B (pt)
AT (1) ATE490270T1 (pt)
AU (1) AU2007278894B2 (pt)
BR (1) BRPI0715331B8 (pt)
CA (1) CA2658806C (pt)
CY (1) CY1111630T1 (pt)
DE (1) DE602007010969D1 (pt)
DK (1) DK2076532T3 (pt)
ES (1) ES2361455T3 (pt)
GB (1) GB0614755D0 (pt)
HK (1) HK1131162A1 (pt)
HR (1) HRP20110146T1 (pt)
ME (1) ME01320B (pt)
MX (1) MX2009000918A (pt)
NZ (1) NZ575092A (pt)
PL (1) PL2076532T3 (pt)
PT (1) PT2076532E (pt)
RS (1) RS51854B (pt)
RU (1) RU2461567C2 (pt)
SI (1) SI2076532T1 (pt)
WO (1) WO2008012689A2 (pt)
ZA (1) ZA200901342B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT201600091033A1 (it) * 2016-09-08 2018-03-08 Bioimmunizer Sagl Ceppi di batteri probiotici appartenenti al genere Bifidobacterium e loro estratti di cellule probiotiche (ECP) aventi proprietà immunostimolanti.
MX2020012782A (es) * 2018-05-28 2021-04-28 ORION Biotechnology Switzerland Sarl Inhibidor de ccr5 para el uso en el tratamiento de cancer.
CA3101052A1 (en) * 2018-05-28 2019-12-05 ORION Biotechnology Switzerland Sarl Methods of inhibiting cerebral inflammation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9406821A (pt) * 1993-06-09 1996-03-26 Connaught Lab Peptideo sintético composiçao imunogenica kit de diagnostico útil para dectar anticorpos especificos de hiv em amostra de teste kit de diagnostico para detectar antigenos de hiv em amostra de teste codificaçao de molécula de ácido nucléico e anticorpo
FR2748938B1 (fr) 1996-05-22 1998-07-31 Pasteur Institut Utilisation de molecules antagonistes de chemokines pour leur activite antivirale notamment contre un retrovirus de type vih
UA77950C2 (en) 2000-10-04 2007-02-15 Applied Research Systems Use of mutants of cc chemokines for treatment of multiple sclerosis
US20030049603A1 (en) 2001-09-05 2003-03-13 Guy Gorochov Methods for construction and screening of libraries of chemokine variants
US7442512B2 (en) * 2001-11-30 2008-10-28 Chemocentryx, Inc. Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors
WO2005112567A2 (en) 2004-05-03 2005-12-01 University Of Maryland Biotechnology Institute Vaginal microbicide

Also Published As

Publication number Publication date
JP5224603B2 (ja) 2013-07-03
AU2007278894B2 (en) 2012-08-09
CN101511867B (zh) 2014-04-09
ME01320B (me) 2013-12-20
US20090317363A1 (en) 2009-12-24
KR101530353B1 (ko) 2015-06-26
BRPI0715331B1 (pt) 2021-04-13
WO2008012689A3 (en) 2008-05-08
KR20090060281A (ko) 2009-06-11
CA2658806C (en) 2017-01-03
US8686111B2 (en) 2014-04-01
EP2076532B1 (en) 2010-12-01
RS51854B (en) 2012-02-29
HK1131162A1 (en) 2010-01-15
WO2008012689A2 (en) 2008-01-31
RU2461567C2 (ru) 2012-09-20
AU2007278894A1 (en) 2008-01-31
US20130330305A1 (en) 2013-12-12
ATE490270T1 (de) 2010-12-15
MX2009000918A (es) 2009-08-26
CY1111630T1 (el) 2015-10-07
CA2658806A1 (en) 2008-01-31
PT2076532E (pt) 2011-03-02
EP2076532A2 (en) 2009-07-08
DK2076532T3 (da) 2011-03-07
CN101511867A (zh) 2009-08-19
HRP20110146T1 (hr) 2011-06-30
PL2076532T3 (pl) 2011-07-29
GB0614755D0 (en) 2006-09-06
RU2009106436A (ru) 2010-08-27
US9328153B2 (en) 2016-05-03
NZ575092A (en) 2011-08-26
SI2076532T1 (sl) 2011-06-30
BRPI0715331A2 (pt) 2013-07-16
DE602007010969D1 (de) 2011-01-13
ZA200901342B (en) 2010-11-24
ES2361455T3 (es) 2011-06-17
JP2009544304A (ja) 2009-12-17

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Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: MINTAKA FOUNDATION FOR MEDICAL RESEARCH (CH)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B25A Requested transfer of rights approved

Owner name: ORION BIOTECHNOLOGY SWITZERLAND SARL (CH)

B25G Requested change of headquarter approved

Owner name: ORION BIOTECHNOLOGY SWITZERLAND SARL (CH)

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 25/07/2007, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME MEDIDA CAUTELAR DE 07/04/2021 - ADI 5.529/DF

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 25/07/2007 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF