ES2421885T3 - Polipéptidos y procedimiento para la detección específica de anticuerpos en pacientes con una infección por Borrelia - Google Patents
Polipéptidos y procedimiento para la detección específica de anticuerpos en pacientes con una infección por BorreliaInfo
- Publication number
- ES2421885T3 ES2421885T3 ES08021660T ES08021660T ES2421885T3 ES 2421885 T3 ES2421885 T3 ES 2421885T3 ES 08021660 T ES08021660 T ES 08021660T ES 08021660 T ES08021660 T ES 08021660T ES 2421885 T3 ES2421885 T3 ES 2421885T3
- Authority
- ES
- Spain
- Prior art keywords
- polypeptides
- antibodies
- patients
- procedure
- specific detection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 6
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 6
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 6
- 206010061591 Borrelia infection Diseases 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000011895 specific detection Methods 0.000 title 1
- 108700023315 OspC Proteins 0.000 abstract 5
- 235000001014 amino acid Nutrition 0.000 abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 235000018417 cysteine Nutrition 0.000 abstract 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 abstract 1
- 235000018102 proteins Nutrition 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/20—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pathology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
Abstract
Proteína que comprende un primer polipéptido de OspC, caracterizada porque el primer polipéptido de OspC está unidoa través de un puente disulfuro con un segundo polipéptido de OspC, formándose el puente disulfuro por unión de unacisteína que no está alejada más de 100 posiciones de aminoácidos del extremo N-terminal del polipéptido de OspC,presentando el primer y el segundo polipéptido de OspC una identidad de aminoácidos de al menos el 70% con la SEC IDNº: 3, SEC ID Nº: 6 o SEC ID Nº: 9.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08021660.9A EP2199303B1 (de) | 2008-12-12 | 2008-12-12 | Polypeptide und Verfahren zur spezifischen Detektion von Antikörpern bei Patienten mit einer Borrelieninfektion |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2421885T3 true ES2421885T3 (es) | 2013-09-06 |
Family
ID=40568393
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES08021660T Active ES2421885T3 (es) | 2008-12-12 | 2008-12-12 | Polipéptidos y procedimiento para la detección específica de anticuerpos en pacientes con una infección por Borrelia |
Country Status (4)
Country | Link |
---|---|
US (2) | US8163500B2 (es) |
EP (1) | EP2199303B1 (es) |
ES (1) | ES2421885T3 (es) |
PL (1) | PL2199303T3 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2959971A1 (de) | 2014-06-27 | 2015-12-30 | Euroimmun Medizinische Labordiagnostika AG | Verfahren und Vorrichtung zur Überführung von Flüssigkeiten |
US11061028B2 (en) | 2014-09-24 | 2021-07-13 | Defined Diagnostics, Llc | Compositions and methods for the diagnosis of lyme disease |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991009870A1 (de) | 1989-12-22 | 1991-07-11 | Mikrogen Molekularbiologische Entwicklungs-Gmbh | Immunologisch aktive proteine von borrelia burgdorferi, zusammenhängende testkits und impfstoff |
US5620862A (en) * | 1993-11-24 | 1997-04-15 | University Of Connecticut | Methods for diagnosing early Lyme disease |
EP1741718A3 (en) | 1995-06-07 | 2007-03-28 | Sanofi Pasteur Inc. | Expression of lipoproteins |
ATE232212T1 (de) | 1996-05-02 | 2003-02-15 | Dako As | Verwendung von aus osp-c abgeleiteten peptidefragmenten für diagnostische methoden |
AT405940B (de) * | 1996-06-21 | 1999-12-27 | Immuno Ag | Verfahren zur gewinnung und reinigung von rekombinantem, nicht-lipidiertem osp-protein |
-
2008
- 2008-12-12 EP EP08021660.9A patent/EP2199303B1/de not_active Revoked
- 2008-12-12 ES ES08021660T patent/ES2421885T3/es active Active
- 2008-12-12 PL PL08021660T patent/PL2199303T3/pl unknown
-
2009
- 2009-12-11 US US12/636,530 patent/US8163500B2/en active Active
-
2012
- 2012-03-22 US US13/427,181 patent/US8431135B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
PL2199303T3 (pl) | 2013-11-29 |
US20100150964A1 (en) | 2010-06-17 |
US8431135B2 (en) | 2013-04-30 |
EP2199303B1 (de) | 2013-06-05 |
US20120177680A1 (en) | 2012-07-12 |
US8163500B2 (en) | 2012-04-24 |
EP2199303A1 (de) | 2010-06-23 |
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