PT2034985E - Combinação dum inibidor de redutase hmg-coa e dum inibidor de sintase de farnesil-pirofosfatase para tratar doenças relacionadas com a acumulação e/ou a persistência de proteínas preniladas - Google Patents
Combinação dum inibidor de redutase hmg-coa e dum inibidor de sintase de farnesil-pirofosfatase para tratar doenças relacionadas com a acumulação e/ou a persistência de proteínas preniladas Download PDFInfo
- Publication number
- PT2034985E PT2034985E PT78038494T PT07803849T PT2034985E PT 2034985 E PT2034985 E PT 2034985E PT 78038494 T PT78038494 T PT 78038494T PT 07803849 T PT07803849 T PT 07803849T PT 2034985 E PT2034985 E PT 2034985E
- Authority
- PT
- Portugal
- Prior art keywords
- pyrophosphatase
- farnesyl
- hmg
- persistence
- accumulation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Birds (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Toxicology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0606097A FR2903312B1 (fr) | 2006-07-05 | 2006-07-05 | Utilisation d'inhibiteurs d'hmg-coa reductase et de farnesyl-pyrophosphate synthase dans la preparation d'un medicament |
Publications (1)
Publication Number | Publication Date |
---|---|
PT2034985E true PT2034985E (pt) | 2015-09-23 |
Family
ID=37729451
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT78038494T PT2034985E (pt) | 2006-07-05 | 2007-07-05 | Combinação dum inibidor de redutase hmg-coa e dum inibidor de sintase de farnesil-pirofosfatase para tratar doenças relacionadas com a acumulação e/ou a persistência de proteínas preniladas |
PT15160222T PT2921172T (pt) | 2006-07-05 | 2007-07-05 | Combinação dum inibidor de redutase hmg-coa e dum inibidor de sintase de farnesil-pirofosfatase para tratar doenças relacionadas com a acumulação e/ou a persistência de proteinas preniladas |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT15160222T PT2921172T (pt) | 2006-07-05 | 2007-07-05 | Combinação dum inibidor de redutase hmg-coa e dum inibidor de sintase de farnesil-pirofosfatase para tratar doenças relacionadas com a acumulação e/ou a persistência de proteinas preniladas |
Country Status (11)
Country | Link |
---|---|
US (3) | US8518914B2 (pt) |
EP (2) | EP2921172B1 (pt) |
JP (2) | JP5363979B2 (pt) |
DK (2) | DK2921172T3 (pt) |
ES (2) | ES2543719T3 (pt) |
FR (1) | FR2903312B1 (pt) |
HK (1) | HK1214965A1 (pt) |
PL (2) | PL2034985T3 (pt) |
PT (2) | PT2034985E (pt) |
TR (1) | TR201815511T4 (pt) |
WO (1) | WO2008003864A1 (pt) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2903312B1 (fr) * | 2006-07-05 | 2008-09-26 | Univ Aix Marseille Ii | Utilisation d'inhibiteurs d'hmg-coa reductase et de farnesyl-pyrophosphate synthase dans la preparation d'un medicament |
FR2926020B1 (fr) * | 2008-01-03 | 2010-08-13 | Univ Aix Marseille Ii | Composition cosmetique et/ou dermatologique |
AU2013251237B2 (en) * | 2008-01-03 | 2016-03-17 | Universite D' Aix-Marseille | Bitherapy and tritherapy used for treating an HIV-positive patient |
DK2234620T3 (en) * | 2008-01-03 | 2016-06-06 | Université D'aix-Marseille | Triple therapy used for treatment of an hiv-infected patient |
EP2261214A1 (en) | 2009-06-12 | 2010-12-15 | Splicos Sas | Compounds useful to treat premature aging and in particular progeria |
US10253020B2 (en) | 2009-06-12 | 2019-04-09 | Abivax | Compounds for preventing, inhibiting, or treating cancer, AIDS and/or premature aging |
HUE061262T2 (hu) | 2009-06-12 | 2023-05-28 | Abivax | Splicing mechanizmust gátló új kémiai molekulák splicing hibákból betegségek kezelésére |
JPWO2012046772A1 (ja) * | 2010-10-06 | 2014-02-24 | 国立大学法人 東京大学 | リンパ浮腫予防治療剤 |
EP2465502A1 (en) | 2010-12-15 | 2012-06-20 | Société Splicos | Compounds useful for treating AIDS |
EP2757161A1 (en) | 2013-01-17 | 2014-07-23 | Splicos | miRNA-124 as a biomarker of viral infection |
US10835513B2 (en) | 2013-06-28 | 2020-11-17 | The Regents Of The University Of California | Methods and treatments for the learning and memory deficits associated with Noonan syndrome |
CN105530938B (zh) | 2013-07-05 | 2019-10-22 | Abivax公司 | 用于治疗由逆转录病毒引起的疾病的化合物 |
EP2974729A1 (en) | 2014-07-17 | 2016-01-20 | Abivax | Quinoline derivatives for use in the treatment of inflammatory diseases |
EP3212194A4 (en) * | 2014-10-29 | 2018-06-20 | University Of Maryland | Methods of treating age-related symptoms in mammals and compositions therefor |
EP3669873A1 (en) | 2018-12-20 | 2020-06-24 | Abivax | Quinoline derivatives for use ine the traeatment of inflammation diseases |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0526936A3 (en) * | 1991-08-02 | 1993-05-05 | Merck & Co. Inc. | Cholesterol-lowering agents |
US20030105121A1 (en) | 1999-07-27 | 2003-06-05 | Bernard Bihari | Method of preventing lipodystrophy syndrome or reversing a pre-existing syndrome in HIV-infected patients being treated with antiretroviral agents |
JP2001253827A (ja) | 2000-02-15 | 2001-09-18 | Pfizer Prod Inc | 骨粗鬆症を治療するための組成物および方法 |
AU2001268653A1 (en) | 2000-06-28 | 2002-01-08 | Supergen, Inc. | Combination hiv therapy including camptothecin |
FR2825706B1 (fr) * | 2001-06-06 | 2003-12-12 | Pf Medicament | Nouveaux derives de benzothienyle ou d'indole, leur preparation et leur utilisation comme inhibiteurs de proteines prenyl transferase |
MY169670A (en) | 2003-09-03 | 2019-05-08 | Tibotec Pharm Ltd | Combinations of a pyrimidine containing nnrti with rt inhibitors |
US20060275294A1 (en) * | 2002-08-22 | 2006-12-07 | Omoigui Osemwota S | Method of prevention and treatment of aging, age-related disorders and/or age-related manifestations including atherosclerosis, peripheral vascular disease, coronary artery disease, osteoporosis, arthritis, type 2 diabetes, dementia, alzheimers disease and cancer |
US20060078531A1 (en) | 2004-10-12 | 2006-04-13 | Osemwota Sota | Method of prevention and treatment of atherosclerosis, peripheral vascular disease, coronary artery disease, and age-related disorders including osteoporosis, arthritis, type 2 diabetes, dementia and Alzheimer's disease |
GB0220885D0 (en) | 2002-09-09 | 2002-10-16 | Novartis Ag | Organic compounds |
ES2209658B1 (es) | 2002-12-05 | 2005-10-01 | Proyecto Empresarial Brudy, S.L. | Utilizacion del acido docosahexaenoico como principio activo para el tratamiento de la lipodistrofia. |
US20050020517A1 (en) | 2002-12-16 | 2005-01-27 | Boehringer Ingelheim Pharmaceuticals, Inc. | Treatment of HIV infection through combined administration of tipranavir and capravirine |
EA200601392A1 (ru) | 2004-01-29 | 2006-12-29 | Апплайд Резеч Системз Арс Холдинг Н. В. | Способы и композиции для лечения липодистрофии |
FR2866724B1 (fr) * | 2004-02-20 | 2007-02-16 | Atmel Nantes Sa | Dispositif de generation d'une tension electrique de reference de precision amelioree et circuit integre electronique correspondant |
FR2903312B1 (fr) * | 2006-07-05 | 2008-09-26 | Univ Aix Marseille Ii | Utilisation d'inhibiteurs d'hmg-coa reductase et de farnesyl-pyrophosphate synthase dans la preparation d'un medicament |
FR2926020B1 (fr) | 2008-01-03 | 2010-08-13 | Univ Aix Marseille Ii | Composition cosmetique et/ou dermatologique |
-
2006
- 2006-07-05 FR FR0606097A patent/FR2903312B1/fr not_active Expired - Fee Related
-
2007
- 2007-07-05 PL PL07803849T patent/PL2034985T3/pl unknown
- 2007-07-05 DK DK15160222.4T patent/DK2921172T3/en active
- 2007-07-05 PL PL15160222T patent/PL2921172T3/pl unknown
- 2007-07-05 ES ES07803849.4T patent/ES2543719T3/es active Active
- 2007-07-05 ES ES15160222T patent/ES2702062T3/es active Active
- 2007-07-05 JP JP2009517336A patent/JP5363979B2/ja not_active Expired - Fee Related
- 2007-07-05 TR TR2018/15511T patent/TR201815511T4/tr unknown
- 2007-07-05 EP EP15160222.4A patent/EP2921172B1/fr not_active Not-in-force
- 2007-07-05 PT PT78038494T patent/PT2034985E/pt unknown
- 2007-07-05 EP EP07803849.4A patent/EP2034985B1/fr not_active Not-in-force
- 2007-07-05 WO PCT/FR2007/001144 patent/WO2008003864A1/fr active Application Filing
- 2007-07-05 US US12/307,220 patent/US8518914B2/en not_active Expired - Fee Related
- 2007-07-05 PT PT15160222T patent/PT2921172T/pt unknown
- 2007-07-05 DK DK07803849.4T patent/DK2034985T3/en active
-
2013
- 2013-04-25 JP JP2013092855A patent/JP2013166776A/ja active Pending
- 2013-06-19 US US13/922,055 patent/US9072757B2/en not_active Expired - Fee Related
-
2014
- 2014-12-18 US US14/575,814 patent/US20150105352A1/en not_active Abandoned
-
2016
- 2016-03-15 HK HK16103013.9A patent/HK1214965A1/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO2008003864A1 (fr) | 2008-01-10 |
FR2903312B1 (fr) | 2008-09-26 |
JP2013166776A (ja) | 2013-08-29 |
DK2034985T3 (en) | 2015-08-03 |
EP2034985B1 (fr) | 2015-05-06 |
US20100120720A1 (en) | 2010-05-13 |
EP2034985A1 (fr) | 2009-03-18 |
EP2921172B1 (fr) | 2018-09-12 |
FR2903312A1 (fr) | 2008-01-11 |
PL2921172T3 (pl) | 2019-06-28 |
HK1214965A1 (zh) | 2016-08-12 |
US20150105352A1 (en) | 2015-04-16 |
JP2009541475A (ja) | 2009-11-26 |
DK2921172T3 (en) | 2018-10-22 |
US9072757B2 (en) | 2015-07-07 |
ES2543719T3 (es) | 2015-08-21 |
TR201815511T4 (tr) | 2018-11-21 |
PT2921172T (pt) | 2018-11-09 |
US8518914B2 (en) | 2013-08-27 |
ES2702062T3 (es) | 2019-02-27 |
US20130281408A1 (en) | 2013-10-24 |
EP2921172A1 (fr) | 2015-09-23 |
PL2034985T3 (pl) | 2015-10-30 |
JP5363979B2 (ja) | 2013-12-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1214965A1 (zh) | 還原酶抑制劑和法尼基焦磷酸酶合成酶抑制劑的組合用於治療與異戊二烯基化的蛋白的持續存在和/或積累相關的疾病 | |
IL191997A0 (en) | Inhibitors of iap | |
IL232786A0 (en) | Inhibitors of e1 enzyme activators | |
HK1139036A1 (en) | Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases | |
ZA200802585B (en) | Pyridopyrimidinone inhibitors of Pl3Kα | |
IL190292A0 (en) | PYRIDOPYRIMIDINONE INHIBITORS OF P13Ka | |
SG152225A1 (en) | Inhibitors of iap | |
IL179854A0 (en) | Inhibitors of iap | |
GB0903608D0 (en) | Systems and methods for calibration of heart sounds | |
EP2180891A4 (en) | COMBINATION PREPARATION WITH HMG COA REDUCTASE INHIBITORS AND ASPIRIN AND METHOD FOR THE PRODUCTION THEREOF | |
EP2007383A4 (en) | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | |
SI1833995T1 (sl) | Identifikacija tarč RNA z uporabo helikaz | |
IL193335A0 (en) | Method for geolocalization of one or more targets | |
GB2443533B (en) | Determination of sensor distance | |
ZA200806937B (en) | Combination of triazine derivatives and HMG-CoA reductase inhibitors for the treatment of diabetes | |
IL187730A0 (en) | Azolopyridine-2-on derivatives as lipase and phospholipase inhibitors | |
IL187728A0 (en) | Benzooxazole-2-on derivatives as lipase and phospholipase inhibitors | |
IL187729A0 (en) | Benzothiazol-2-on derivatives as lipase and phospholipase inhibitors | |
SI1937696T1 (sl) | Postopek za pripravo zaviralcev HMG-CoA reduktaz | |
EP2212874A4 (en) | DEVICE FOR MONITORING AND LOCATING SEMI-TRAILERS | |
EP2049102A4 (en) | POLYMORPHIC FORMS OF AN HMG COA REDUCTASE HEATHER AND USE | |
EP1871396A4 (en) | STABILIZED PHARMACEUTICAL COMPOSITIONS WITH AN HMG COA REDUCTASE INHIBITOR | |
AU2013248173A1 (en) | Inhibitors of IAP | |
ZA201006157B (en) | Modified release formulations of hmg coa reductase inhibitors | |
AU2005906584A0 (en) | Use of Inhibitors of Prolyl-4-Hydroxylases |