PT1981859E - Preparação de delmopinol - Google Patents

Preparação de delmopinol

Info

Publication number
PT1981859E
PT1981859E PT77048882T PT07704888T PT1981859E PT 1981859 E PT1981859 E PT 1981859E PT 77048882 T PT77048882 T PT 77048882T PT 07704888 T PT07704888 T PT 07704888T PT 1981859 E PT1981859 E PT 1981859E
Authority
PT
Portugal
Prior art keywords
delmopinol
preparation
Prior art date
Application number
PT77048882T
Other languages
English (en)
Inventor
Llorenc Rafecas Jane
Alexander Comely
Nicolas Tesson
Atoni Escale Riera
Original Assignee
Sinclair Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sinclair Pharmaceuticals Ltd filed Critical Sinclair Pharmaceuticals Ltd
Publication of PT1981859E publication Critical patent/PT1981859E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C11/00—Aliphatic unsaturated hydrocarbons
    • C07C11/02—Alkenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/16—Preparation of halogenated hydrocarbons by replacement by halogens of hydroxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C19/00—Acyclic saturated compounds containing halogen atoms
    • C07C19/075—Acyclic saturated compounds containing halogen atoms containing bromine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/06—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings
    • C07D265/08—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/04—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
PT77048882T 2006-02-07 2007-01-10 Preparação de delmopinol PT1981859E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0602424.4A GB0602424D0 (en) 2006-02-07 2006-02-07 Compounds

Publications (1)

Publication Number Publication Date
PT1981859E true PT1981859E (pt) 2013-01-31

Family

ID=36119632

Family Applications (1)

Application Number Title Priority Date Filing Date
PT77048882T PT1981859E (pt) 2006-02-07 2007-01-10 Preparação de delmopinol

Country Status (13)

Country Link
US (2) US7893258B2 (pt)
EP (1) EP1981859B1 (pt)
JP (2) JP2009525315A (pt)
CN (1) CN101379047B (pt)
CY (1) CY1113799T1 (pt)
DK (1) DK1981859T3 (pt)
ES (1) ES2398249T3 (pt)
GB (1) GB0602424D0 (pt)
HK (1) HK1125934A1 (pt)
PL (1) PL1981859T3 (pt)
PT (1) PT1981859E (pt)
SI (1) SI1981859T1 (pt)
WO (1) WO2007091009A2 (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7838708B2 (en) 2001-06-20 2010-11-23 Grt, Inc. Hydrocarbon conversion process improvements
RU2366642C2 (ru) 2003-07-15 2009-09-10 Джи Ар Ти, Инк. Синтез углеводородов
US20050171393A1 (en) 2003-07-15 2005-08-04 Lorkovic Ivan M. Hydrocarbon synthesis
US20060100469A1 (en) 2004-04-16 2006-05-11 Waycuilis John J Process for converting gaseous alkanes to olefins and liquid hydrocarbons
US7244867B2 (en) 2004-04-16 2007-07-17 Marathon Oil Company Process for converting gaseous alkanes to liquid hydrocarbons
US7674941B2 (en) 2004-04-16 2010-03-09 Marathon Gtf Technology, Ltd. Processes for converting gaseous alkanes to liquid hydrocarbons
US20080275284A1 (en) 2004-04-16 2008-11-06 Marathon Oil Company Process for converting gaseous alkanes to liquid hydrocarbons
US8642822B2 (en) 2004-04-16 2014-02-04 Marathon Gtf Technology, Ltd. Processes for converting gaseous alkanes to liquid hydrocarbons using microchannel reactor
US8173851B2 (en) 2004-04-16 2012-05-08 Marathon Gtf Technology, Ltd. Processes for converting gaseous alkanes to liquid hydrocarbons
EA020442B1 (ru) 2006-02-03 2014-11-28 ДжиАрТи, ИНК. Способ превращения углеводородного сырья (варианты) и система для его осуществления
CN101395088B (zh) 2006-02-03 2012-04-04 Grt公司 轻气体与卤素的分离方法
JP2010528054A (ja) 2007-05-24 2010-08-19 ジーアールティー インコーポレイテッド 可逆的なハロゲン化水素の捕捉及び放出を組み込んだ領域反応器
US8282810B2 (en) 2008-06-13 2012-10-09 Marathon Gtf Technology, Ltd. Bromine-based method and system for converting gaseous alkanes to liquid hydrocarbons using electrolysis for bromine recovery
US8415517B2 (en) 2008-07-18 2013-04-09 Grt, Inc. Continuous process for converting natural gas to liquid hydrocarbons
US8198495B2 (en) 2010-03-02 2012-06-12 Marathon Gtf Technology, Ltd. Processes and systems for the staged synthesis of alkyl bromides
US8367884B2 (en) 2010-03-02 2013-02-05 Marathon Gtf Technology, Ltd. Processes and systems for the staged synthesis of alkyl bromides
US8815050B2 (en) 2011-03-22 2014-08-26 Marathon Gtf Technology, Ltd. Processes and systems for drying liquid bromine
US8436220B2 (en) 2011-06-10 2013-05-07 Marathon Gtf Technology, Ltd. Processes and systems for demethanization of brominated hydrocarbons
US8829256B2 (en) 2011-06-30 2014-09-09 Gtc Technology Us, Llc Processes and systems for fractionation of brominated hydrocarbons in the conversion of natural gas to liquid hydrocarbons
US8802908B2 (en) 2011-10-21 2014-08-12 Marathon Gtf Technology, Ltd. Processes and systems for separate, parallel methane and higher alkanes' bromination
US9193641B2 (en) 2011-12-16 2015-11-24 Gtc Technology Us, Llc Processes and systems for conversion of alkyl bromides to higher molecular weight hydrocarbons in circulating catalyst reactor-regenerator systems
US20150010479A1 (en) 2012-03-20 2015-01-08 Sinclair Pharmaceuticals Limited Treatment of microbial infections
CN103382393A (zh) * 2013-06-20 2013-11-06 佛山科学技术学院 一类含氮、磷液态反应型阻燃剂及其制备方法
WO2017202635A1 (en) 2016-05-25 2017-11-30 Basf Se Semiconductors
IT201600130538A1 (it) * 2016-12-23 2018-06-23 Lundbeck Pharmaceuticals Italy S P A Processo per la produzione del delmopinolo
IT201600130642A1 (it) 2016-12-23 2018-06-23 Lundbeck Pharmaceuticals Italy S P A Processo per la produzione di 2(3 alchilmorfolino)-etan-1-olo
IT201600130729A1 (it) * 2016-12-23 2018-06-23 Lundbeck Pharmaceuticals Italy S P A Processo per la produzione degli intermedi del delmopinolo
IT201700076821A1 (it) 2017-08-24 2019-02-24 Lundbeck Pharmaceuticals Italy S P A Nuovo sale del delmopinolo
EP3470388A1 (en) * 2017-10-13 2019-04-17 Basf Se Synthesis of aliphatic alcohols as aroma chemicals
US11877590B2 (en) 2019-03-27 2024-01-23 Fiedler & Lundgren Ab Smokeless tobacco composition
JP7424685B2 (ja) * 2020-01-31 2024-01-30 ユー ファースト サービシズ インコーポレイテッド デルモピノール及びその塩の製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3502627A (en) * 1966-01-06 1970-03-24 Rohm & Haas N-acryl(polyoxyalkyl)-oxazolidines and n - acryl(polyoxyalkyl) - tetrahydro-1,3-oxazines and salts thereof
SE439011B (sv) * 1980-03-21 1985-05-28 Ferrosan Ab Morfolinoforeningar, kompositioner innehallande dessa och anvendning derav
WO1990014342A1 (en) * 1989-05-24 1990-11-29 Pharmacia Ab Substituted isoxazolidines and isoxazolines

Also Published As

Publication number Publication date
WO2007091009A3 (en) 2007-11-15
CN101379047A (zh) 2009-03-04
US7893258B2 (en) 2011-02-22
CN101379047B (zh) 2011-07-13
US20110082301A1 (en) 2011-04-07
JP2014144968A (ja) 2014-08-14
US8093398B2 (en) 2012-01-10
DK1981859T3 (da) 2013-01-21
GB0602424D0 (en) 2006-03-22
JP2009525315A (ja) 2009-07-09
WO2007091009A2 (en) 2007-08-16
US20090036677A1 (en) 2009-02-05
HK1125934A1 (en) 2009-08-21
PL1981859T3 (pl) 2013-05-31
CY1113799T1 (el) 2016-07-27
ES2398249T3 (es) 2013-03-14
EP1981859A2 (en) 2008-10-22
SI1981859T1 (sl) 2013-03-29
JP5726347B2 (ja) 2015-05-27
EP1981859B1 (en) 2012-10-31

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