PT1558641E - Cristais de análogos de insulina e processo para a sua preparação - Google Patents

Cristais de análogos de insulina e processo para a sua preparação Download PDF

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Publication number
PT1558641E
PT1558641E PT03757992T PT03757992T PT1558641E PT 1558641 E PT1558641 E PT 1558641E PT 03757992 T PT03757992 T PT 03757992T PT 03757992 T PT03757992 T PT 03757992T PT 1558641 E PT1558641 E PT 1558641E
Authority
PT
Portugal
Prior art keywords
crystals
angstrom
chain
production
amino acid
Prior art date
Application number
PT03757992T
Other languages
English (en)
Inventor
Harald Berchtold
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of PT1558641E publication Critical patent/PT1558641E/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2299/00Coordinates from 3D structures of peptides, e.g. proteins or enzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT03757992T 2002-10-29 2003-10-16 Cristais de análogos de insulina e processo para a sua preparação PT1558641E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10250297A DE10250297A1 (de) 2002-10-29 2002-10-29 Kristalle von Insulinanaloga und Verfahren zu ihrer Herstellung

Publications (1)

Publication Number Publication Date
PT1558641E true PT1558641E (pt) 2010-04-19

Family

ID=32114902

Family Applications (1)

Application Number Title Priority Date Filing Date
PT03757992T PT1558641E (pt) 2002-10-29 2003-10-16 Cristais de análogos de insulina e processo para a sua preparação

Country Status (15)

Country Link
EP (1) EP1558641B1 (pt)
JP (1) JP4460454B2 (pt)
AT (1) ATE458755T1 (pt)
AU (1) AU2003274018B2 (pt)
BR (1) BR0315764A (pt)
CA (1) CA2503670A1 (pt)
CY (1) CY1112016T1 (pt)
DE (2) DE10250297A1 (pt)
DK (1) DK1558641T3 (pt)
ES (1) ES2340157T3 (pt)
IL (1) IL168141A (pt)
MX (1) MXPA05004440A (pt)
PT (1) PT1558641E (pt)
SI (1) SI1558641T1 (pt)
WO (1) WO2004039838A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005269753B2 (en) * 2004-07-19 2011-08-18 Biocon Limited Insulin-oligomer conjugates, formulations and uses thereof
EP2804621A4 (en) * 2012-01-20 2015-11-18 Univ Case Western Reserve GLUTAMINE-SAFE STABILIZED INSULIN ANALOG

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5597893A (en) * 1994-10-31 1997-01-28 Eli Lilly And Company Preparation of stable insulin analog crystals
ATE321783T1 (de) * 1997-03-20 2006-04-15 Novo Nordisk As Zinkfreie insulinkristalle für die verwendung in medikamenten, die über die lunge verabreicht werden.
DE19726167B4 (de) * 1997-06-20 2008-01-24 Sanofi-Aventis Deutschland Gmbh Insulin, Verfahren zu seiner Herstellung und es enthaltende pharmazeutische Zubereitung
DE10114178A1 (de) * 2001-03-23 2002-10-10 Aventis Pharma Gmbh Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität

Also Published As

Publication number Publication date
MXPA05004440A (es) 2005-07-26
AU2003274018B2 (en) 2009-08-20
ATE458755T1 (de) 2010-03-15
BR0315764A (pt) 2005-09-06
EP1558641A1 (de) 2005-08-03
DE10250297A1 (de) 2004-05-19
JP2006516536A (ja) 2006-07-06
DK1558641T3 (da) 2010-06-07
EP1558641B1 (de) 2010-02-24
DE50312454D1 (de) 2010-04-08
CA2503670A1 (en) 2004-05-13
WO2004039838A1 (de) 2004-05-13
IL168141A (en) 2012-12-31
SI1558641T1 (sl) 2010-04-30
CY1112016T1 (el) 2015-11-04
AU2003274018A1 (en) 2004-05-25
ES2340157T3 (es) 2010-05-31
JP4460454B2 (ja) 2010-05-12

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