PT1505965E - Uso de valsartan ou do seu metabolito para inibir a agragação de plaquetas - Google Patents

Uso de valsartan ou do seu metabolito para inibir a agragação de plaquetas Download PDF

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Publication number
PT1505965E
PT1505965E PT03749892T PT03749892T PT1505965E PT 1505965 E PT1505965 E PT 1505965E PT 03749892 T PT03749892 T PT 03749892T PT 03749892 T PT03749892 T PT 03749892T PT 1505965 E PT1505965 E PT 1505965E
Authority
PT
Portugal
Prior art keywords
valsartan
valeryl
platelet aggregation
metabolite
platelet
Prior art date
Application number
PT03749892T
Other languages
English (en)
Portuguese (pt)
Inventor
Alex Malinin
Victor L Serebruany
Randy Lee Webb
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29423705&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1505965(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PT1505965E publication Critical patent/PT1505965E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT03749892T 2002-05-14 2003-05-13 Uso de valsartan ou do seu metabolito para inibir a agragação de plaquetas PT1505965E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38037302P 2002-05-14 2002-05-14
US39501402P 2002-07-11 2002-07-11

Publications (1)

Publication Number Publication Date
PT1505965E true PT1505965E (pt) 2006-11-30

Family

ID=29423705

Family Applications (1)

Application Number Title Priority Date Filing Date
PT03749892T PT1505965E (pt) 2002-05-14 2003-05-13 Uso de valsartan ou do seu metabolito para inibir a agragação de plaquetas

Country Status (22)

Country Link
US (2) US20050197372A1 (https=)
EP (1) EP1505965B1 (https=)
JP (1) JP4467427B2 (https=)
KR (1) KR101005367B1 (https=)
CN (1) CN100408035C (https=)
AT (1) ATE334677T1 (https=)
AU (1) AU2003267447B8 (https=)
BR (1) BR0310018A (https=)
CA (1) CA2482541A1 (https=)
CY (1) CY1105638T1 (https=)
DE (1) DE60307265T2 (https=)
DK (1) DK1505965T3 (https=)
ES (1) ES2268403T3 (https=)
IL (2) IL164774A0 (https=)
MX (1) MXPA04011282A (https=)
NO (1) NO20045245L (https=)
NZ (1) NZ536295A (https=)
PL (1) PL371728A1 (https=)
PT (1) PT1505965E (https=)
RU (1) RU2334512C2 (https=)
TW (1) TWI299663B (https=)
WO (1) WO2003094915A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040265238A1 (en) * 2003-06-27 2004-12-30 Imtiaz Chaudry Inhalable formulations for treating pulmonary hypertension and methods of using same
TW200523257A (en) * 2003-09-26 2005-07-16 Novartis Ag Use of organic compounds
AR057882A1 (es) 2005-11-09 2007-12-26 Novartis Ag Compuestos de accion doble de bloqueadores del receptor de angiotensina e inhibidores de endopeptidasa neutra
AR068814A1 (es) * 2007-08-29 2009-12-09 Orion Corp Composicion farmaceutica que comprende levosimendan y un inhibidor de la enzima conversina de la angiotensina (ace), y uso
RU2410104C1 (ru) * 2009-07-10 2011-01-27 Учреждение Российской академии медицинских наук Научный центр неврологии РАМН СПОСОБ СНИЖЕНИЯ АГРЕГАЦИОННОЙ АКТИВНОСТИ ТРОМБОЦИТОВ in vitro
US10478404B2 (en) 2014-01-24 2019-11-19 Arizona Board Of Regents On Behalf Of The University Of Arizona Materials, methods and devices for altering cell reactivity
CN110078640B (zh) * 2019-03-29 2022-04-05 浙江美诺华药物化学有限公司 一种缬沙坦中间体的合成方法
CN111643557B (zh) * 2020-05-26 2022-02-22 四川省骨科医院 一种防治下肢深静脉血栓后遗症期的药物组合物及其制备方法和用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE312198T1 (de) * 1993-04-05 2005-12-15 Univ Utah Res Found Diagnose und behandlung von supravalvular aortic stenosis
US6395728B2 (en) * 1999-07-08 2002-05-28 Novartis Ag Method of treatment and pharmaceutical composition
CA2379666C (en) * 1999-07-21 2009-10-13 Takeda Chemical Industries, Ltd. Agent for preventing recurrence of cerebrovascular disorder and agent for ameliorating troubles following cerebrovascular disorder and inhibiting progress thereof
AU2001267404A1 (en) * 2000-05-04 2001-11-12 Ipf Pharmaceuticals Gmbh Novel compounds for the treatment of inflammatory and cardiovascular diseases
NZ522953A (en) * 2000-06-22 2005-10-28 Novartis Ag Tablet containing valsartan, microcrystalline cellulose, crospovidone, colloidal anhydrous silica/colloidal silicon dioxide and magnesium stearate

Also Published As

Publication number Publication date
AU2003267447A1 (en) 2003-11-11
KR20050000532A (ko) 2005-01-05
JP4467427B2 (ja) 2010-05-26
ATE334677T1 (de) 2006-08-15
DE60307265T2 (de) 2007-07-19
CN1652774A (zh) 2005-08-10
HK1074395A1 (en) 2005-11-11
PL371728A1 (en) 2005-06-27
CY1105638T1 (el) 2010-12-22
TW200410686A (en) 2004-07-01
AU2003267447B8 (en) 2009-08-06
NZ536295A (en) 2006-12-22
US20100048654A1 (en) 2010-02-25
JP2005529913A (ja) 2005-10-06
MXPA04011282A (es) 2005-01-25
AU2003267447B2 (en) 2006-11-02
WO2003094915A1 (en) 2003-11-20
BR0310018A (pt) 2005-02-15
CA2482541A1 (en) 2003-11-20
KR101005367B1 (ko) 2010-12-30
IL164774A0 (en) 2005-12-18
DK1505965T3 (da) 2006-11-13
EP1505965A1 (en) 2005-02-16
RU2334512C2 (ru) 2008-09-27
RU2004136583A (ru) 2005-09-10
IL164774A (en) 2010-04-29
US20050197372A1 (en) 2005-09-08
ES2268403T3 (es) 2007-03-16
DE60307265D1 (de) 2006-09-14
CN100408035C (zh) 2008-08-06
TWI299663B (en) 2008-08-11
EP1505965B1 (en) 2006-08-02
NO20045245L (no) 2004-11-30

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