PT1499410E - Preparação de cristais pequenos - Google Patents

Preparação de cristais pequenos Download PDF

Info

Publication number
PT1499410E
PT1499410E PT03720684T PT03720684T PT1499410E PT 1499410 E PT1499410 E PT 1499410E PT 03720684 T PT03720684 T PT 03720684T PT 03720684 T PT03720684 T PT 03720684T PT 1499410 E PT1499410 E PT 1499410E
Authority
PT
Portugal
Prior art keywords
suspension
crystals
spray
crystal
liquid
Prior art date
Application number
PT03720684T
Other languages
English (en)
Portuguese (pt)
Inventor
Linda Jane Mccausland
David Reay
Original Assignee
Prosonix Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/GB2002/002006 external-priority patent/WO2002089942A1/en
Application filed by Prosonix Ltd filed Critical Prosonix Ltd
Publication of PT1499410E publication Critical patent/PT1499410E/pt

Links

Classifications

    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26DRYING
    • F26BDRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B3/00Drying solid materials or objects by processes involving the application of heat
    • F26B3/02Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air
    • F26B3/10Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air the gas or vapour carrying the materials or objects to be dried with it
    • F26B3/12Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air the gas or vapour carrying the materials or objects to be dried with it in the form of a spray, i.e. sprayed or dispersed emulsions or suspensions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1688Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D1/00Evaporating
    • B01D1/16Evaporating by spraying
    • B01D1/18Evaporating by spraying to obtain dry solids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D9/00Crystallisation
    • B01D9/0018Evaporation of components of the mixture to be separated
    • B01D9/0027Evaporation of components of the mixture to be separated by means of conveying fluid, e.g. spray-crystallisation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D9/00Crystallisation
    • B01D9/005Selection of auxiliary, e.g. for control of crystallisation nuclei, of crystal growth, of adherence to walls; Arrangements for introduction thereof
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D9/00Crystallisation
    • B01D9/005Selection of auxiliary, e.g. for control of crystallisation nuclei, of crystal growth, of adherence to walls; Arrangements for introduction thereof
    • B01D9/0054Use of anti-solvent
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D9/00Crystallisation
    • B01D9/0059General arrangements of crystallisation plant, e.g. flow sheets
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D9/00Crystallisation
    • B01D9/0081Use of vibrations, e.g. ultrasound
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S117/00Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor
    • Y10S117/901Levitation, reduced gravity, microgravity, space

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Drying Of Solid Materials (AREA)
  • Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)
PT03720684T 2002-05-02 2003-04-08 Preparação de cristais pequenos PT1499410E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/GB2002/002006 WO2002089942A1 (en) 2001-05-05 2002-05-02 Formation of small crystals
GBGB0219815.8A GB0219815D0 (en) 2002-08-24 2002-08-24 Preparation of small crystals

Publications (1)

Publication Number Publication Date
PT1499410E true PT1499410E (pt) 2009-04-08

Family

ID=9942964

Family Applications (1)

Application Number Title Priority Date Filing Date
PT03720684T PT1499410E (pt) 2002-05-02 2003-04-08 Preparação de cristais pequenos

Country Status (12)

Country Link
US (1) US7326294B2 (cg-RX-API-DMAC7.html)
EP (1) EP1499410B1 (cg-RX-API-DMAC7.html)
JP (1) JP2005524519A (cg-RX-API-DMAC7.html)
AT (1) ATE421900T1 (cg-RX-API-DMAC7.html)
AU (1) AU2003224261A1 (cg-RX-API-DMAC7.html)
DE (1) DE60326037D1 (cg-RX-API-DMAC7.html)
DK (1) DK1499410T3 (cg-RX-API-DMAC7.html)
ES (1) ES2321919T3 (cg-RX-API-DMAC7.html)
GB (1) GB0219815D0 (cg-RX-API-DMAC7.html)
PT (1) PT1499410E (cg-RX-API-DMAC7.html)
SI (1) SI1499410T1 (cg-RX-API-DMAC7.html)
WO (1) WO2003092851A1 (cg-RX-API-DMAC7.html)

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JP5154078B2 (ja) * 2003-02-21 2013-02-27 ザ ユニヴァーシティ オブ バース 粒子の製造プロセス
JP2005177746A (ja) * 2003-11-28 2005-07-07 Mitsubishi Chemicals Corp 有機化合物微粒子の製造方法
CN1878602A (zh) * 2003-11-28 2006-12-13 三菱化学株式会社 有机化合物微粒的制造方法
GB0415237D0 (en) * 2004-07-07 2004-08-11 Accentus Plc Formation of sugar coatings
JP4586581B2 (ja) * 2005-03-07 2010-11-24 株式会社Ihi 脱リン装置
EP1782797A1 (en) * 2005-11-02 2007-05-09 Pharmatex Italia Srl Process for the preparation of sterile powdered pharmaceutical compounds.
WO2008035962A1 (en) * 2006-09-19 2008-03-27 Fujifilm Manufacturing Europe B.V. Process and device for the precipitation of an organic compound
EP2063970A1 (en) * 2006-09-19 2009-06-03 FUJIFILM Manufacturing Europe B.V. Preparation of fine particles
CN101534952B (zh) * 2006-11-02 2012-10-31 欧姆瑞克斯生物医药有限公司 微粉化方法
GB0705159D0 (en) 2007-03-19 2007-04-25 Prosonix Ltd Process for making crystals
GB0714223D0 (en) * 2007-07-20 2007-08-29 Fujifilm Mfg Europe Bv Preparation of fine particles
US8771524B2 (en) * 2008-02-08 2014-07-08 Purac Biochem B.V. Vortex mixer and method of obtaining a supersaturated solution or slurry
CA2729644C (en) * 2008-07-18 2018-05-29 Prosonix Limited Process for improving crystallinity
GB0900080D0 (en) 2009-01-06 2009-02-11 Prosonix Ltd An apparatus and process for producing crystals
US20130037977A1 (en) * 2010-04-08 2013-02-14 Paul A. Burke Preparation of Lipid Nanoparticles
DE102010017490A1 (de) * 2010-06-21 2011-12-22 WME Gesellschaft für windkraftbetriebene Meerwasserentsalzung mbH Verfahren zur Aufbereitung eines salzhaltigen Rohwassers zur Herstellung eines Prozesswassers, damit hergestelltes Prozesswasser und Vorrichtung zur Durchführung des Verfahrens
US8708159B2 (en) * 2011-02-16 2014-04-29 Oakwood Laboratories, Llc Manufacture of microspheres using a hydrocyclone
EP2500072A1 (en) 2011-03-15 2012-09-19 LEK Pharmaceuticals d.d. A novel process of residual solvent removal
US20140031557A1 (en) * 2011-04-18 2014-01-30 Hefeibeinie Medical Technology Company, Ltd. Method for purification of calcium channel blockers of dihydorpyridine type and preparation of nanoparticles thereof
US9855538B2 (en) 2013-03-08 2018-01-02 The Board Of Trustees Of The University Of Illinois Ultrasonic method and apparatus for producing particles having a controlled size distribution
CN115160090B (zh) * 2022-07-06 2023-05-12 西安近代化学研究所 一种基于微流控技术的hmx超细化制备方法及制备系统

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US2396689A (en) * 1942-12-10 1946-03-19 American Cyanamid Co Spray crystallizing apparatus
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US4489503A (en) * 1980-11-28 1984-12-25 Olin Corporation Process for drying wet particles of available halogen compounds
JP2789751B2 (ja) 1989-12-27 1998-08-20 住友化学工業株式会社 ベルヌーイ法単結晶用原料アルミナの製造法
GB9007027D0 (en) 1990-03-29 1990-05-30 Atomic Energy Authority Uk Precipitation apparatus and method
US6582728B1 (en) * 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
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DE10137017A1 (de) * 2001-07-30 2003-02-20 Basf Ag Kristallisationsverfahren zur Einstellung kleiner Partikel
US20030106488A1 (en) * 2001-12-10 2003-06-12 Wen-Chiang Huang Manufacturing method for semiconductor quantum particles

Also Published As

Publication number Publication date
DK1499410T3 (da) 2009-06-02
DE60326037D1 (de) 2009-03-19
GB0219815D0 (en) 2002-10-02
ES2321919T3 (es) 2009-06-15
EP1499410A1 (en) 2005-01-26
EP1499410B1 (en) 2009-01-28
SI1499410T1 (sl) 2009-06-30
WO2003092851A1 (en) 2003-11-13
US7326294B2 (en) 2008-02-05
AU2003224261A1 (en) 2003-11-17
US20050155541A1 (en) 2005-07-21
ATE421900T1 (de) 2009-02-15
JP2005524519A (ja) 2005-08-18

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